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T8727TH1020interaction,inhibit,Bacterial,flagellin,TH-1020,TH1020,Toll-like Receptor (TLR),TLR5,protein-p
TH1020 is a novel Inhibitor of Toll-Like Receptor 5 (TLR5)/Flagellin Complex with promising activity (IC50 =0.85±0.12 μm) and specificity.
价 格:¥电议型 号:T8727产 地:中国大陆
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T7798FGH10019FGH10019,FGH 10019,inhibit,Inhibitor,Fatty Acid Synthase (FASN)
FGH-10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM).
价 格:¥电议型 号:T7798产 地:中国大陆
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T9532MRT-81Smo,Smoothened,human,C3H10T1/2 cells,inhibit,Shh-light2 cells,rodent,BODIPY-cyclopamine,MRT81,
MRT-81 inhibits human and rodent smoothened?Smo?receptors effectively with an IC50?value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 also can be used for the research of cancer[1].
价 格:¥电议型 号:T9532产 地:中国大陆
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T60034TH1085Inhibitor,DNA glycosylase 1 (OGG1),TH-10785,TH 10785,DNA oxidative lesions,TH1085,enzyme,pheny
TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).
价 格:¥电议型 号:T60034产 地:中国大陆
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T60076Oritinibpharmacodynamics,non-small cell lung cancer,EGFR-T790M,EGFR TKI,SH1028,Irreversible,mutant-s
Oritinib is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can be used in studies about the treatment of non-small cell lung cancer.
价 格:¥电议型 号:T60076产 地:中国大陆
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T4138UCPH-101UCPH 101;UCPH101
UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with an IC50 of 0.66 μM.
价 格:¥电议型 号:T4138产 地:中国大陆
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T2451GlyH-101GlyH 101;GlyH101
GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM.
价 格:¥电议型 号:T2451产 地:中国大陆
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T17877VH032-cyclopropane-FPhenolic VH101;VHL ligand 3;E3 ligase Ligand 19
VH032-cyclopropane-F is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.
价 格:¥电议型 号:T17877产 地:中国大陆
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T0236Azatadine dimaleateAzatadine Maleate;SCH10649;马来酸阿扎他啶;马来酸阿扎他定
Azatadine dimaleate is an inhibitor for histamine(IC50=6.5 nM) and cholinergic(IC50=10 nM).
价 格:¥电议型 号:T0236产 地:中国大陆
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T0236Azatadine MaleateAzatadine Maleate,Azatadine dimaleate,SCH10649
Azatadine dimaleate is an inhibitor for histamine(IC50=6.5 nM) and cholinergic(IC50=10 nM).
价 格:¥电议型 号:T0236产 地:美洲
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T12366PARP14 inhibitor H10PARP14 inhibitor H10
PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM
价 格:¥电议型 号:T12366产 地:美洲
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T12714ReversanReversan,CBLC4H10,
Reversan is a potent and nontoxic multidrug inhibitor of resistance-associated protein 1 (MRP1) and P-glycoprotein (Pgp).
价 格:¥电议型 号:T12714产 地:美洲
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T15745LexacalcitolLexacalcitol,KH1060,
Lexacalcitol is over 100 times more active than 1alpha,25-dihydroxyvitamin D3 [1alpha,25-(OH)2D3], as judged by in vitro antiproliferative and cell differentiating assays.
价 格:¥电议型 号:T15745产 地:美洲
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T2451GlyH-101GlyH-101,GlyH101,GlyH 101
GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM.
价 格:¥电议型 号:T2451产 地:美洲
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T8727TH1020;化合物TH1020TH1020
TH1020 is a novel Inhibitor of Toll-Like Receptor 5 (TLR5)/Flagellin Complex with promising activity (IC50 =0.85±0.12 μm) and specificity.
价 格:¥电议型 号:T8727产 地:中国大陆
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T82880Biotin-H10;化合物 Biotin-H10Biotin-H10
Biotin-H10 is a potent inhibitor of anterior gradient homolog 2 (AGR2) with a dissociation constant (K_D) of 6.4 nM, effectively reducing the viability of cancer cells [1].
价 格:¥电议型 号:T82880产 地:中国大陆
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T7798FGH10019;化合物FGH-10019FGH-10019;FGH-10019
FGH10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM).
价 格:¥电议型 号:T7798产 地:中国大陆
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T70903KRH102053;化合物 KRH102053KRH102053
KRH102053 is a HIF-1alpha inhibitor. KRH102053 decreased the protein level of HIF-1alpha and the mRNA levels of HIF-regulated downstream target genes, such as vascular endothelial growth factor, aldolase A, enolase 1 and monocarboxylate transporter 4. Consistent with these results, KRH102053 also inhibited the rates of HIF-related migration and invasion of HOS cells as well as the degree of tube formation in human umbilical vein endothelium cells.
价 格:¥电议型 号:T70903产 地:中国大陆
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T70121Zavondemstat;化合物 ZavondemstatQC8222|||TACH 101|||TACH101;QC8222|||TACH 101|||TACH101
Zavondemstat, a compound exhibiting antineoplastic activity, functions as an inhibitor of the histone lysine demethylase 4D (KDM4D).
价 格:¥电议型 号:T70121产 地:中国大陆
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T68511KRH102140;化合物 KRH102140KRH102140
KRH102140 is a potent activator of PHD2. KRH102140, which has a structure similar to KRH102053. KRH102140 more efficiently suppressed HIF-1α than KRH102053 in human osteosarcoma cells under hypoxia. Furthermore, KRH102140 decreased the mRNA levels of HIF-regulated downstream target genes associated with angiogenesis and energy metabolism such as vascular endothelial growth factor, adrenomedullin, Glut1, aldolase A, enolase 1 and monocarboxylate transporter 4. KRH102140 also inhibited tube format
价 格:¥电议型 号:T68511产 地:中国大陆