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T8508HDAC-IN-3Histone deacetylases,Inhibitor,inhibit,HDAC,HDACIN3,HDAC IN 3
HDAC-IN-3 is a potent histone deacetylase (HDAC) inhibitor, and treatment chronic inflammatory disorders.
价 格：￥电议型 号：T8508产 地：中国大陆
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T8508HDAC-IN-3；化合物HDAC-IN-3GSK3117391A；GSK3117391A
HDAC-IN-3 (GSK3117391A) is a potent histone deacetylase (HDAC) inhibitor, and treatment chronic inflammatory disorders.
价 格：￥电议型 号：T8508产 地：中国大陆
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T78906CDK/HDAC-IN-3；化合物 CDK/HDAC-IN-3CDK/HDAC-IN-3
CDK/HDAC-IN-3 is an orally active dual inhibitor of HDACs and CDKs, offering potent and selective inhibition of CDK9, CDK12, CDK13, HDAC1, HDAC2, and HDAC3, with IC50 values of 98.32 nM, 98.85 nM, 100 nM, 62.12 nM, 93.28 nM, and 82.87 nM, respectively. This compound is applicable in the treatment of acute myeloid leukemia (AML) [1].
价 格：￥电议型 号：T78906产 地：中国大陆
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T78880Tubulin/HDAC-IN-3；化合物 Tubulin/HDAC-IN-3Tubulin/HDAC-IN-3
Tubulin/HDAC-IN-3 (compound 12a) serves as a potent dual inhibitor of tubulin polymerization and HDAC1/8, exhibiting IC50 values of 5.4 μM for tubulin polymerization, and 0.155 and 0.177 μM for HDAC1 and HDAC8, respectively. Its mechanism of action includes obstructing the cell cycle, triggering apoptosis, and suppressing colony formation [1].
价 格：￥电议型 号：T78880产 地：中国大陆
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T72777c-Met/HDAC-IN-3；化合物 c-Met/HDAC-IN-3c-Met/HDAC-IN-3
c-Met/HDAC-IN-3, a dual inhibitor targeting both c-Met and HDAC, exhibits potent inhibitory activity with IC50 values of 12.50 nM for c-Met and 26.97 nM for HDAC1. It induces apoptosis and causes cell cycle arrest in the G2/M phase.
价 格：￥电议型 号：T72777产 地：中国大陆
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T63791HDAC-IN-36；化合物 HDAC-IN-36HDAC-IN-36
HDAC-IN-36 is an orally active HDAC (histone deacetylase) inhibitor with an IC50 value of 11.68 nM for HDAC6. HDAC-IN-36 induces apoptosis, autophagy and inhibits migration. HDAC-IN-36 exhibits antitumor and antimetastatic effects and can be used to study breast cancer. HDAC-IN-36 exhibits antitumor and antimetastatic effects and can be used to study breast cancer.
价 格：￥电议型 号：T63791产 地：中国大陆
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T63416HDAC-IN-39；化合物 HDAC-IN-39HDAC-IN-39
HDAC-IN-39 is a potent inhibitor of HDAC and is able to act on HDAC1, HDAC2 and HDAC3 with IC50 values of 1.07 μM, 1.47 μM and 2.27 μM, respectively. HDAC-IN-39 induces cell cycle arrest in G2/M phase and also significantly inhibits microtubule polymerization. HDAC-IN-39 exhibits good anticancer effects on HDAC-IN-39 exhibited good anti-cancer effects on drug-resistant cancer cells.
价 格：￥电议型 号：T63416产 地：中国大陆
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T62920HDAC-IN-38；化合物 HDAC-IN-38HDAC-IN-38
HDAC-IN-38 is a potent inhibitor of HDAC. HDAC-IN-38 has similar micromolar inhibitory effects on HDAC1, 2, 3, 5, 6 and 8, and also increases histone acetylation levels (H3K14 or H4K5). HDAC-IN-38 increases cerebral blood flow (CBF), reduces cognitive impairment and improves hippocampal atrophy.
价 格：￥电议型 号：T62920产 地：中国大陆
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T62708HDAC-IN-37；化合物 HDAC-IN-37HDAC-IN-37
HDAC-IN-37 is a potent inhibitor of HDAC, acting on HDAC1 (IC50: 0.0551 μM), HDAC3 (IC50: 1.24 μM), HDAC8 (IC50: 0.948 μM) and HDAC6 (IC50: 34.2 μM). HDAC-IN-37 is able to slowly induce histone acetylation. HDAC-IN-37 prevents the transition from G1 to S phase and induces early apoptosis.
价 格：￥电议型 号：T62708产 地：中国大陆
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T62649HDAC-IN-34；化合物 HDAC-IN-34HDAC-IN-34
HDAC-IN-34 (compound 27) is a potent inhibitor of HDAC that acts on HDAC1 (IC50: 0.022 μM) and HDAC6 (IC50: 0.45 μM). HDAC-IN-34 can bind to DNA and cause DNA damage. HDAC-IN-34 exhibits a significant anti-proliferative effect on HCT-116 cells (IC50: 1.41 μM).
价 格：￥电议型 号：T62649产 地：中国大陆
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T62109HDAC-IN-31；化合物 HDAC-IN-31HDAC-IN-31
HDAC-IN-31 is a selective, potent, orally active HDAC inhibitor that acts on HDAC1 (IC50: 84.90 nM), HDAC2 (IC50: 168.0 nM), HDAC3 (IC50: 442.7 nM), HDAC8 (IC50>10000 nM). HDAC-IN-31 has good anti-tumour effects. HDAC-IN-31 has shown potential research value in diffuse large B-cell lymphoma.
价 格：￥电议型 号：T62109产 地：中国大陆
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T62006HDAC-IN-30；化合物 HDAC-IN-30HDAC-IN-30
HDAC-IN-30 is a multi-target HDAC inhibitor. HDAC-IN-30 inhibits HDAC1 (IC50 =13.4 nM), HDAC2 (IC50 =28.0 nM), HDAC3 (IC50 =9.18 nM), HDAC6 (IC50 =42.7 nM), HDAC8 (IC50 =131 nM). HDAC-IN-30 shows potent antitumor efficacy.
价 格：￥电议型 号：T62006产 地：中国大陆
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T61916HDAC-IN-35；化合物 HDAC-IN-35HDAC-IN-35
HDAC-IN-35 (Compound 14) is an effective and selective inhibitor of VEGFR-2 and HDAC, with IC50 values of 13.2 and 0.166 μM for VEGFR-2 and HDAC6, respectively.
价 格：￥电议型 号：T61916产 地：中国大陆
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T61429HDAC-IN-33；化合物 HDAC-IN-33HDAC-IN-33
HDAC-IN-33 is a highly potent HDAC inhibitor, effectively inhibiting HDAC1, HDAC2, and HDAC6 with IC50 values of 24, 46, and 47 nM, respectively. This compound demonstrates significant antiproliferation activity against tumor cells and exhibits remarkable in vivo antitumor efficacy. Additionally, HDAC-IN-33 initiates the activation of antitumor immunity [1].
价 格：￥电议型 号：T61429产 地：中国大陆
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T61248HDAC-IN-32；化合物 HDAC-IN-32HDAC-IN-32
HDAC-IN-32 is a highly effective HDAC inhibitor presenting IC50 values of 5.2, 11, and 28 nM for HDAC1, HDAC2, and HDAC6, respectively. This compound demonstrates notable anti-proliferative properties against tumor cells, as well as significant in vivo antitumor efficacy, which can elicit antitumor immunity [1].
价 格：￥电议型 号：T61248产 地：中国大陆
