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  • T14860CaMKII-IN-1

    CaMKII-IN-1 is a potent and highly selective inhibitor of CaMKII (IC50 = 63 nM). CaMKII-IN-1 exhibited more than 100-fold higher selectivity for CaMKII over CaMKIV, MLCK, p38a, Akt1, and PKC.

    价 格：￥电议型 号：T14860产 地：中国大陆

  • T14860CaMKII-IN-1CaMKII-IN-1

    CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor (IC50: 63 nM). It has significantly high selectivity against CaMKIV, MLCK, p38a, Akt1, and PKC.

    价 格：￥电议型 号：T14860产 地：美洲

  • T78729hCAIX/VII-IN-1；化合物 hCAIX/VII-IN-1hCAIX/VII-IN-1

    hCAIX/VII-IN-1 is a selective inhibitor of human carbonic anhydrase isoforms VII and IX. It displays inhibitory activity against hCA I, II, IV, VII, and IX, with respective K_i values of 336.2 nM, 185.8 nM, 1055 nM, 35.6 nM, and 28.0 nM. This compound is applicable in cancer and neurological disease research [1].

    价 格：￥电议型 号：T78729产 地：中国大陆

  • T74978DPP IV/hCA II-IN-1；化合物 DPP IV/hCA II-IN-1DPP IV/hCA II-IN-1

    DPP IV/hCA II-IN-1 is a potent, selective inhibitor of dipeptidyl peptidase IV (DPP IV) and carbonic anhydrase (CA), exhibiting an IC50 of 0.049 μM for DPP IV and K_i values of 0.0361, 0.0428, 0.0941, 0.1328, 0.2615, and 3.034 μM for CA II, CA VB, CA VA, CA IX, CA I, and CA IV, respectively [1].

    价 格：￥电议型 号：T74978产 地：中国大陆

  • T74630RNA polymerase II-IN-1；化合物 RNA polymerase II-IN-1RNA polymerase II-IN-1

    RNA polymerase II-IN-1 (compound 19iv), an amatoxin, selectively inhibits RNA polymerase II (Pol II) with an IC50 of 36.66 nM. It exhibits heightened cytotoxicity towards cancer cells and reduced toxicity in normal cells compared to α-Amanitin [1].

    价 格：￥电议型 号：T74630产 地：中国大陆

  • T73033TRK II-IN-1；化合物 TRK II-IN-1TRK II-IN-1

    TRK II-IN-1 is a potent type II inhibitor of tropomyosin receptor kinases (TRK), demonstrating inhibitory half-maximal inhibitory concentrations (IC50s) of 3.3, 6.4, 4.3, and 9.4 nM against TRKA, TRKB, TRKC, and the mutant TRKA G667C, respectively. Additionally, this compound exhibits IC50 values of 1.3 nM against FLT3, 9.9 nM against RET, and 71.1 nM against VEGFR2. TRK II-IN-1 primarily serves as a research tool for studying TRK-driven cancers [1].

    价 格：￥电议型 号：T73033产 地：中国大陆

  • T63805β-Glucuronidase/hCAII-IN-1；化合物 β-Glucuronidase/hCAII-IN-1β-Glucuronidase/hCAII-IN-1

    β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a compound that effectively inhibits both β-glucuronidase and human Carbonic Anhydrase II (hCA II), exhibiting IC50 values of 440.1 μM and 4.91 μM, respectively [1].

    价 格：￥电议型 号：T63805产 地：中国大陆

  • T63752hCAII-IN-1；化合物 hCAII-IN-1hCAII-IN-1

    hCAII-IN-1 (compound 7f) is a selective and potent inhibitor of carbonic anhydrase (CA II/IX) with their Kis values of 1.2 and 113.6 nM, respectively. hCAII-IN-1 has shown investigational potential for cancer disease.

    价 格：￥电议型 号：T63752产 地：中国大陆

  • T62892hCAI/II-IN-1；化合物 hCAI/II-IN-1hCAI/II-IN-1

    hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor that acts on hCA I (IC50: 0.047 μM) and hCA II (IC50: 0.024 μM).

    价 格：￥电议型 号：T62892产 地：中国大陆

  • T62423GCPII-IN-1 TFA；化合物 GCPII-IN-1 TFAGCPII-IN-1 TFA

    GCPII-IN-1 TFA is a glutamate carboxypeptidase II (GCPII; PSMA) inhibitor scaffold (Ki: 44.3 nM).

    价 格：￥电议型 号：T62423产 地：中国大陆

  • T61981Human carbonic anhydrase II-IN-1；化合物 Human carbonic anhydrase II-IN-1Human carbonic anhydrase II-IN-

    Human carbonic anhydrase II-IN-1 (Compound S-13) is a potent human carbonic anhydrase II (hCA II) inhibitor. Human carbonic anhydrase II-IN-1 shows Kis of 4.4 nM, 9.2 nM, 480.2 nM and 14.7 nM for hCA II, I, IV and IX, respectively. Human carbonic anhydrase II-IN-1 can be used for glaucoma research.

    价 格：￥电议型 号：T61981产 地：中国大陆

  • T61873hCAIX/XII-IN-1；化合物 hCAIX/XII-IN-1hCAIX/XII-IN-1

    hCAIX/XII-IN-1, a potent inhibitor of both CAIX and CAXII, exhibits KI values of 0.48 μM for CAIX and 0.83 μM for CAXII, respectively. This compound demonstrates antiproliferative activity in vitro and induces apoptosis in MCF-7 cells [1].

    价 格：￥电议型 号：T61873产 地：中国大陆

  • T61292CAII-IN-1；化合物 CAII-IN-1CAII-IN-1

    CAII-IN-1 (compound 3n) is a thiosemicarbazide derivative that acts as a potent and selective inhibitor of carbonic anhydrase-II (CA-II), with an IC50 value of 10.3 μM for bovine CA-II. This compound (CAII-IN-1) finds utility in research pertaining to carbonic anhydrase-associated biological disorders [1].

    价 格：￥电议型 号：T61292产 地：中国大陆

  • T61219hCAXII-IN-1；化合物 hCAXII-IN-1hCAXII-IN-1

    hCAXII-IN-1 demonstrates selective inhibition of tumor-related subtypes HCA IX and XII, making it potential leading molecules in the development of novel cancer therapeutic drugs with new mechanisms of action.

    价 格：￥电议型 号：T61219产 地：中国大陆

  • T61009Complex III-IN-1；化合物 Complex III-IN-1Complex III-IN-1

    Complex III-IN-1 (Compd 4c-2) is an inhibitor of complex III with antifungal activity. The EC50 value of Complex III-IN-1 against sclerotinia sclerotiorum is 18.53 mg/L [1].

    价 格：￥电议型 号：T61009产 地：中国大陆

  • T60991Factor VII-IN-1；化合物 Factor VII-IN-1Factor VII-IN-1

    Factor VII-IN-1 (example 43) has anticoagulant activities that is a potent factor VII (FVII) inhibitor with an IC50 value of 1.1 μM [1].

    价 格：￥电议型 号：T60991产 地：中国大陆

  • T60930CAXII-IN-1；化合物 CAXII-IN-1CAXII-IN-1

    CAXII-IN-1 (Compound 17) has antitumor activity that is a selective inhibitor of CA XII. The Ki values of CAXII-IN-1 for hCA XII and hCA IX is 3.8 nM and 56.0 nM, respectively [1].

    价 格：￥电议型 号：T60930产 地：中国大陆

  • T60450AChE/hCA I/II-IN-1；化合物 AChE/hCA I/II-IN-1AChE/hCA I/II-IN-1

    AChE/hCA I/II-IN-1 (Compound 6) is a potent AChE/Hca inhibitor with IC50 values of 22.21, 60.79 and 66.64 nM for AChE, Hca Ⅰ and Hca Ⅱ. AChE/hCA I/II-IN-1 can be used in glaucoma, Alzheimer´s disease, and diabetes rsearch[1].

    价 格：￥电议型 号：T60450产 地：中国大陆

  • T38420GCPII-IN-1；GCPII-IN-1GCPII-IN-1

    GCPII-IN-1 is a potent inhibitor scaffold targeting glutamate carboxypeptidase II (GCPII), also known as prostate-specific membrane antigen (PSMA). It exhibits a high affinity for GCPII, with a binding affinity (K i ) of 44.3 nanomolar (nM).

    价 格：￥电议型 号：T38420产 地：中国大陆

  • T14860CaMKII-IN-1；化合物CaMKII-IN-1CaMKII-IN-1

    CaMKII-IN-1 is a potent and highly selective inhibitor of CaMKII (IC50 = 63 nM). CaMKII-IN-1 exhibited more than 100-fold higher selectivity for CaMKII over CaMKIV, MLCK, p38a, Akt1, and PKC.

    价 格：￥电议型 号：T14860产 地：中国大陆

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