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T39544IPN60090 dihydrochlorideIPN60090 dihydrochlorideIPN60090 dihydrochloride
IPN-60090 dihydrochloride is a potent and specific inhibitor of glutaminase 1 (GLS1) with a remarkable inhibition constant (IC50) of 31 nM. It does not exhibit any inhibitory activity against GLS-2. Furthermore, IPN-60090 dihydrochloride possesses outstanding physicochemical properties and pharmacokinetic characteristics in vivo. Therefore, it is a valuable compound for researching solid tumors, including lung and ovarian cancers.
价 格:¥电议型 号:T39544产 地:中国大陆
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T11412IPN60090;化合物IPN60090GLS1-IN-1;GLS1-IN-1
IPN60090 is a novel, potent, orally bioavailable, renal-type glutaminase (GLS1)-specific inhibitor with an IC50 value of 31 nM for GLS1. IPN60090 has potential anticancer and immunostimulant/immunomodulatory activity, selectively targets, binds, and inhibits human glutaminase, and can be used to study GLS1-mediated diseases.
价 格:¥电议型 号:T11412产 地:中国大陆