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T75125ITK degrader 2；化合物 ITK degrader 2ITK degrader 2
ITK Degrader 2 (Compound 30) functions as a modulator for targeted ubiquitination and serves as a molecule for targeted protein degradation, specifically degrading ITK [1].
价 格：￥电议型 号：T75125产 地：中国大陆
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T74843ITK degrader 1；化合物 ITK degrader 1ITK degrader 1
ITK Degrader 1, a highly selective interleukin-2-inducible T-cell kinase (ITK; DC50=3.6 nM in vivo in mice) degrader, induces rapid and prolonged degradation of ITK and effectively suppresses IL-2 secretion (EC50=35.2 nM, Jurkat cells) stimulated by anti-CD3 antibody in vivo. Additionally, it demonstrates favorable plasma exposure levels [1].
价 格：￥电议型 号：T74843产 地：中国大陆
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T72397PARP11 inhibitor ITK7；化合物 PARP11 inhibitor ITK7ITK7；ITK7
PARP11 Inhibitor ITK7 (ITK7) is a potent, selective inhibitor of PARP11, demonstrating significant efficacy with an IC50 value of 14 nM. It is primarily utilized in research focused on cellular localization.
价 格：￥电议型 号：T72397产 地：中国大陆
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T63229ITK inhibitor 6；化合物 ITK inhibitor 6ITK inhibitor 6
ITK inhibitor 6 is a selective and potent ITK inhibitor that acts on ITK (IC50: 4 nM), BTK (IC50: 133 nM), JAK3 (IC50: 320 nM), EGFR (IC50: 2360 nM), LCK (IC50: 155 nM). ITK inhibitor 6 inhibited the phosphorylation of PLCγ1 and ERK1/2 and showed anti-proliferative effect.
价 格：￥电议型 号：T63229产 地：中国大陆
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T40294ITK/TRKA-IN-1；ITK/TRKA-IN-1ITK/TRKA-IN-1
ITK/TRKA-IN-1 is a chemical compound that functions as a dual inhibitor of IL-2-inducible T-cell kinase (ITK) and tropomyosin receptor kinase A (TRKA). With an IC50 value of 1.0 nM, it effectively inhibits the activity of ITK, while demonstrating a remarkable 96% inhibition of TRKA.
价 格：￥电议型 号：T40294产 地：中国大陆
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T37604ITK inhibitor；ITK inhibitorITK inhibitor
Interleukin-2-inducible T cell kinase (ITK) is a non-receptor tyrosine kinase expressed in T cells, NKT cells and mast cells which plays a crucial role in regulating the T cell receptor (TCR), CD28, CD2, chemokine receptor CXCR4, and FcepsilonR-mediated signaling pathways. ITK inhibitors can be used for the treatment of inflammation and immune-mediated disorders. ITK inhibitor (N-[5-[[3-[(4-Acetylpiperazin-1-yl)carbonyl]-4-methyl-6-methoxy-phenyl]thio]thiazol-2-yl]-4-(N-1,2-dimethylpropylaminome
价 格：￥电议型 号：T37604产 地：中国大陆
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T11690ITK inhibitor 2；化合物 T11690ITK inhibitor 2
ITK inhibitor 2 is a interleukin-2-inducible T-cell kinase (ITK) inhibitor , with an IC50 of 2 nM.
价 格：￥电议型 号：T11690产 地：中国大陆
