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  • T82234hCAIX-IN-19;化合物 hCAIX-IN-19hCAIX-IN-19

    hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/hCAIX = 117).

    价 格:¥电议型 号:T82234产 地:中国大陆

  • T74955hCAIX-IN-13;化合物 hCAIX-IN-13hCAIX-IN-13

    hCAIX-IN-13 (Pt2), a Carbonic Anhydrase IX (CAIX) inhibitor, demonstrates a notable IC50 value of 6.57 μM, efficiently impeding cancer cell growth and promoting apoptosis. It is valuable for cancer research [1].

    价 格:¥电议型 号:T74955产 地:中国大陆

  • T74486hCAIX-IN-17;化合物 hCAIX-IN-17hCAIX-IN-17

    Compound 6f, also known as hCA IX-IN-1, is a human carbonic anhydrase (hCA) inhibitor that exhibits varying inhibitory effectiveness across different hCA isoforms, with K i values of 331.4 nM for hCA I, 28.4 nM for hCA II, 9.4 nM for hCA IX, and 17.8 nM for hCA XII. It is notable for its anticancer activity [1].

    价 格:¥电议型 号:T74486产 地:中国大陆

  • T73030hCAIX-IN-14;化合物 hCAIX-IN-14hCAIX-IN-14

    hCAIX-IN-14 is a potent inhibitor of human CA IX with a K i value of 134.8 nM [1] .

    价 格:¥电议型 号:T73030产 地:中国大陆

  • T73029hCAIX-IN-15;化合物 hCAIX-IN-15hCAIX-IN-15

    hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancer activity suitable for cancer research [1].

    价 格:¥电议型 号:T73029产 地:中国大陆

  • T73028hCAIX-IN-16;化合物 hCAIX-IN-16hCAIX-IN-16

    hCAIX-IN-16 (Compound 12d), an inhibitor of hCA IX, exhibits inhibition constants (K i) of 190.0 nM for hCA IX and 187.9 nM for hCA XII. It can arrest the cell cycle in the G0-G1 and S phases and induce apoptosis in MDA-MB-468 breast cancer cells. Demonstrating broad-spectrum anticancer activity, hCAIX-IN-16 is a potential tool for cancer research [1].

    价 格:¥电议型 号:T73028产 地:中国大陆

  • T63764hCA XII/II/IX-IN-1;化合物 hCA XII/II/IX-IN-1hCA XII/II/IX-IN-1

    hCA XII/II/IX-IN-1 is a potent inhibitor of human carbonic anhydrase (hCA) and is able to act on hCA I (IC50: 2.6 μM), hCA II (IC50: 0.004 μM), hCA IX (IC50: 0.005 μM) and hCA XII (IC50: 0.001 μM). hCA XII/II/IX -IN-1 exhibited anticancer effects.

    价 格:¥电议型 号:T63764产 地:中国大陆

  • T63158hCAIX-IN-10;化合物 hCAIX-IN-10hCAIX-IN-10

    hCAIX-IN-10 (Compound 6i) is a selective inhibitor of carbonic anhydrase IX and XII, acting on hCA IX (Ki: 61.5 nM) and hCA XII (Ki: 586.8 nM). hCA IX and hCA XII are transmembrane isoforms of carbonic anhydrase that act as biomarkers for some types of tumours. hCA XII contributes to the maintenance of acid-base homeostasis in normal and tumour cells.

    价 格:¥电议型 号:T63158产 地:中国大陆

  • T62387CA IX-IN-1;化合物 CA IX-IN-1CA IX-IN-1

    CA IX-IN-1 (compound 12g) is a potent and highly selective hCA IX inhibitor (IC50: 7 nM) that exhibits antitumour effects.

    价 格:¥电议型 号:T62387产 地:中国大陆

  • T62026hCAIX-IN-11;化合物 hCAIX-IN-11hCAIX-IN-11

    hCAIX-IN-11 (Compound 5d) is a selective carbonic anhydrase IX and XII inhibitor. hCAIX-IN-11 shows K i s of 32.7 and 623.5 nM for hCA IX and hCA XII, respectively.

    价 格:¥电议型 号:T62026产 地:中国大陆

  • T61896hCAIX-IN-12;化合物 hCAIX-IN-12hCAIX-IN-12

    hCAIX-IN-12 is an effective hCAIX inhibitor, IC50 for CAIX and CAII is 0.74 and 10.78 μM , respectively. hCAIX-IN-12 inhibits cell proliferation and induces apoptosis. HCAIX-IN-12 can increase the generation of ROS. HCAIX-IN-12 has research potential in colorectal cancer (CRC).

    价 格:¥电议型 号:T61896产 地:中国大陆

  • T61263hCA IX-IN-1;化合物 hCA IX-IN-1hCA IX-IN-1

    hCA IX-IN-1 (Compound 6f) is a human carbonic anhydrase ( hCA ) inhibitor with K i values of 331.4, 28.4, 9.4 and 17.8 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. hCA IX-IN-1 shows anticancer activity [1].

    价 格:¥电议型 号:T61263产 地:中国大陆

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