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T7414ARS-853ARS 853,ARS-853,KRAS,Apoptosis,cancer,mutant,state,inhibit,Inhibitor,inactive,Ras,selective,c
ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells
价 格:¥电议型 号:T7414产 地:中国大陆
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T9303MRTX1133KRAS,Ras,MRTX 1133,G12D,cells,active,wild-type,phosphorylation,mutant,MRTX1133,inactive,ERK,
MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D. MRTX1133 exhibits an estimated KD against KRAS G12D of 0.2 pM. MRTX1133 inhibits mutant KRAS-dependent signal transduction by preventing SOS1-catalyzed nucleotide exchange and/or formation of the KRAS G12D/GTP/RAF1 complex. MRTX1133 selectively inhibits KRAS G12D mutant tumor cells with no effect on KRAS wild-type. MRTX1133 exhibits single digit nanomolar activity in cellular assays and marked in vivo efficacy in tumor mode
价 格:¥电议型 号:T9303产 地:中国大陆
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T8543KN-92 hydrochlorideInhibitor,derivative,experimental,inactive,KN-92,KN92 hydrochloride,KN92,inhibit,
KN-92 hydrochloride is an inactive derivative of KN-93. KN-93 is a selective Ca2+/calmodulin-dependent kinase II (CaMKII) inhibitor, competitively blocking CaM binding to the kinase with Ki of 370 nM.
价 格:¥电议型 号:T8543产 地:中国大陆
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T23150PHGDH-inactive
PHGDH inactive is inactive against PHGDH and serves as a negative control for NCT-502 and NCT-503 [1].
价 格:¥电议型 号:T23150产 地:中国大陆
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T36580Glucagon Receptor Antagonist Inactive Control;Glucagon Receptor Antagonist Inactive ControlGlucagon
Glucagon Receptor Antagonist Inactive Control is a Glucagon receptor antagonist that can be used in related research in the field of life sciences. Its product number is T36580 and CAS number is 362482-00-6.
价 格:¥电议型 号:T36580产 地:中国大陆
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T23150PHGDH-inactive;化合物PHGDH-inactivePHGDH-inactive
PHGDH inactive is inactive against PHGDH and serves as a negative control for NCT-502 and NCT-503 [1].
价 格:¥电议型 号:T23150产 地:中国大陆