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  • T38683SCD1 inhibitor-3

    SCD1 inhibitor-3 is a safe, potent and orally active SCD1 inhibitor. SCD1 inhibitor-3 can be used for the research of metabolic diseases such as obesity, type II diabetes and dyslipidemia, as well as skin diseases, acne and cancer.

    价 格：￥电议型 号：T38683产 地：中国大陆

  • T5524Aurora kinase inhibitor-3Aurora Kinase Inhibitor III

    Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.

    价 格：￥电议型 号：T5524产 地：中国大陆

  • T12123mTOR inhibitor-3

    mTOR inhibitor-3 is an inhibitor of remarkably selective mTOR (Ki : 1.5 nM)

    价 格：￥电议型 号：T12123产 地：中国大陆

  • T79277Cysteine protease inhibitor-3；化合物 Cysteine protease inhibitor-3Cysteine protease inhibitor-3

    Cysteine protease inhibitor-3 (Compound 15), a cysteine protease inhibitor, exhibits anti-plasmodial activity, effectively inhibiting Pf3D7 (IC50 = 0.74 μM), PfW2 (IC50 = 1.05 μM), PfFP2 (IC50 = 3.5 μM), and PfFP3 (IC50 = 4.9 μM). It demonstrates efficacy against both drug-sensitive and drug-resistant parasites [1].

    价 格：￥电议型 号：T79277产 地：中国大陆

  • T75024ChoKα inhibitor-3；化合物 ChoKα inhibitor-3ChoKα inhibitor-3

    ChoKα Inhibitor-3, a sulfur-containing choline kinase inhibitor, effectively inhibits HChoK α1 with an IC50 value of 0.66 μM and possesses the capability to induce apoptosis. This compound is utilized in cancer research [1].

    价 格：￥电议型 号：T75024产 地：中国大陆

  • T72714JNK3 inhibitor-3；化合物 JNK3 inhibitor-3JNK3 inhibitor-3

    JNK3 Inhibitor-3 (compound 15g) is a selective, blood-brain barrier permeable, and orally active inhibitor of c-Jun N-terminal kinase 3 (JNK3) with IC50 values of 147.8 nM, 44.0 nM, and 4.1 nM against JNK1, JNK2, and JNK3, respectively. This compound has been shown to significantly enhance memory in mouse models of dementia and is utilized in Alzheimer’s disease research [1].

    价 格：￥电议型 号：T72714产 地：中国大陆

  • T72696UCK2 Inhibitor-3；化合物 UCK2 Inhibitor-3UCK2 Inhibitor-3

    UCK2 Inhibitor-3 is a non-competitive inhibitor targeting uridine-cytidine kinase 2 (UCK2), a key enzyme in the pyrimidine salvage pathway, with an IC50 value of 16.6 μM. Notably, UCK2 can partially substitute for dihydroorotate dehydrogenase (DHODH) in infected or rapidly dividing cells, facilitating effective uridine salvage. Furthermore, UCK2 Inhibitor-3 exhibits inhibition of DNA polymerase eta and kappa, with IC50 values of 56 μM and 16 μM, respectively.

    价 格：￥电议型 号：T72696产 地：中国大陆

  • T72659KRAS inhibitor-3；化合物 KRAS inhibitor-3KRAS inhibitor-3

    KRAS inhibitor-3, an efficacious inhibitor of both wild-type (WT) and oncogenic KRAS mutations, exhibits high-affinity binding (K D: 0.28 μM for KRAS WT, 0.63 μM for KRAS G12C, 0.37 μM for KRAS G12D, and 0.74 μM for KRAS Q61H). Additionally, it impedes the interaction between KRAS and Raf, highlighting its potential as a targeted therapeutic agent in KRAS-mutant cancers.

    价 格：￥电议型 号：T72659产 地：中国大陆

  • T72257BRM/BRG1 ATP Inhibitor-3；化合物 BRM/BRG1 ATP Inhibitor-3BRM/BRG1 ATP Inhibitor-3

    BRM/BRG1 ATP Inhibitor-3 is a potent inhibitor targeting both BRM and BRG1 components of the BAF complex, exhibiting IC50 values of 10.4 nM for BRM and 19.3 nM for BRG1, respectively. It holds potential for research applications in cancer and BAF complex-related disorders.

    价 格：￥电议型 号：T72257产 地：中国大陆

  • T69875ProMMP-9 inhibitor-3c；化合物 ProMMP-9 inhibitor-3cProMMP-9 inhibitor-3c

    ProMMP-9 inhibitor-3c is a potent and specific proMMP-9 inhibitor which disrupts f MMP-9 homodimerization and prevents association of proMMP-9 with both α4β1 integrin and CD44 and results in the dissociation of EGFR.

    价 格：￥电议型 号：T69875产 地：中国大陆

  • T64211GLS1 Inhibitor-3；化合物 GLS1 Inhibitor-3GLS1 Inhibitor-3

    GLS1 Inhibitor-3 (compound C147) is a potent inhibitor of GLS1 (IC50: 27.98 nM) and exhibits anti-proliferative effects.

    价 格：￥电议型 号：T64211产 地：中国大陆

  • T63813HIV-1 inhibitor-39；化合物 HIV-1 inhibitor-39HIV-1 inhibitor-39

    HIV-1 inhibitor-39 is a potent inhibitor of HIV-1 (EC50>112.88 μM). HIV-1 inhibitor-39 has anti-RT (HIV-1 reverse transcriptase) effect (IC50: 15.75 μM). HIV-1 inhibitor-39 exhibits cytotoxicity against MT-4 cells (CC50: 112.9 μM).

    价 格：￥电议型 号：T63813产 地：中国大陆

  • T63306HIV-1 inhibitor-32；化合物 HIV-1 inhibitor-32HIV-1 inhibitor-32

    HIV-1 inhibitor-32 is a potent inhibitor of HIV-1 that acts on wild-type HIV (IC50: 34 nM) and can be used in AIDS research.

    价 格：￥电议型 号：T63306产 地：中国大陆

  • T63171ATM Inhibitor-3；化合物 ATM Inhibitor-3ATM Inhibitor-3

    ATM Inhibitor-3 is a potent and selective inhibitor of ATM (IC50: 0.71 nM). ATM Inhibitor-3 inhibits the PI3K kinase family and exhibits good metabolic stability.

    价 格：￥电议型 号：T63171产 地：中国大陆

  • T62782HIV-1 inhibitor-34；化合物 HIV-1 inhibitor-34HIV-1 inhibitor-34

    HIV-1 inhibitor-34 (compound 5q) is a potent, selective HIV-1 inhibitor that acts on HIV-1 (EC50: 6.4 nM), MT-4 cells (CC50: 16 μM). HIV-1 inhibitor-34 can be used in AIDS research.

    价 格：￥电议型 号：T62782产 地：中国大陆

  • T62425sEH inhibitor-3；化合物 sEH inhibitor-3sEH inhibitor-3

    sEH inhibitor-3 (compound 35) is a potent, orally active inhibitor of soluble epoxide hydrolase (sEH) that acts on human sEH (Ki: 0.75 nM).

    价 格：￥电议型 号：T62425产 地：中国大陆

  • T62353HIV-1 inhibitor-33；化合物 HIV-1 inhibitor-33HIV-1 inhibitor-33

    HIV-1 inhibitor-33 (compound 5n) is a potent and selective HIV-1 inhibitor that acts on HIV-1 (EC50: 8.6 nM), MT-4 cells (CC50: 18 μM). HIV-1 inhibitor-33 can be used in the study of AIDS.

    价 格：￥电议型 号：T62353产 地：中国大陆

  • T62070HIV-1 inhibitor-31；化合物 HIV-1 inhibitor-31HIV-1 inhibitor-31

    HIV-1 inhibitor-31 (compound 4) is a potent inhibitor of HIV-1. HIV-1 inhibitor-31 can be used in the study of AIDS.

    价 格：￥电议型 号：T62070产 地：中国大陆

  • T61801HIV-1 inhibitor-35；化合物 HIV-1 inhibitor-35HIV-1 inhibitor-35

    HIV-1 inhibitor-35 (compound 74) is a highly potent inhibitor of the HIV-1 virus, exhibiting EC50 values of 80 nM and 70 nM for LTR and CMV, respectively, in HEK293 cells. Additionally, HIV-1 inhibitor-35 demonstrates inhibitory activity against HepG2 liver cancer cells, with a CC50 value of 40 nM. Moreover, HIV-1 inhibitor-35 shows promise as a potential HIV-1 latency reversing agent [1].

    价 格：￥电议型 号：T61801产 地：中国大陆

  • T61670HIV-1 inhibitor-38；化合物 HIV-1 inhibitor-38HIV-1 inhibitor-38

    HIV-1 inhibitor-38 (Compound 91) is a powerful agent that inhibits the activity of HIV-1. It exhibits great potential as a novel latency reversing agent, making it a promising candidate for further development [1].

    价 格：￥电议型 号：T61670产 地：中国大陆

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