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T83507[Asn23] β-Amyloid (1-40), Iowa mutation;化合物 [Asn23] β-Amyloid (1-40), Iowa mutation[Asn23] β-Amyloid
[Asn23] β-Amyloid (1-40), Iowa mutation, is a biologically active peptide associated with autosomal dominant Alzheimer´s Disease in multiple families. This specific mutation involves the substitution of Asp 23 with Asn, leading to severe cerebral amyloid beta-protein angiopathy (CAA). Individuals with this mutation exhibit a missense alteration in the APP gene at position 694, which results in the mutated β-amyloid peptide aggregating more quickly and forming toxic fibrils.
价 格:¥电议型 号:T83507产 地:中国大陆
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T83506[Asn23]-beta-Amyloid (1-42), iowa mutation;化合物 [Asn23]-beta-Amyloid (1-42), iowa mutation[Asn23]-bet
[Asn23]-beta-Amyloid (1-42), Iowa mutation, is a biologically active peptide exhibiting increased aggregation propensity and fibril toxicity. This mutation involves the substitution of Aspartic acid (Asp) at position 23 with Asparagine (Asn), contributing to autosomal dominant Alzheimer´s Disease in various kindreds due to its association with severe cerebral amyloid beta-protein angiopathy (CAA). Specifically, the mutation is a missense alteration at position 694 of the amyloid precursor
价 格:¥电议型 号:T83506产 地:中国大陆