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T35900JAK2-IN-7JAK2-IN-7
JAK2-IN-7 is a selective JAK2 inhibitor with IC50s of 3, 11.7, and 41 nM for JAK2, SET-2, and Ba/F3V617F cells, respectively. JAK2-IN-7 possesses >14-fold selectivity over JAK1, JAK3, FLT3. JAK2-IN-7 stimulates cell cycle arrest in the G0/G1 phase and ind
价 格：￥电议型 号：T35900产 地：中国大陆
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T71193Jak2-IN-7j；化合物 Jak2-IN-7jJak2-IN-7j
Jak2-IN-7j is a selective Jak2 inhibitor which demonstrates a time-dependent knock-down of pSTAT5, which is a downstream target of Jak2.
价 格：￥电议型 号：T71193产 地：中国大陆
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T35900JAK2-IN-7；化合物JAK2-IN-7JAK2-IN-7；JAK2-IN-7
JAK2-IN-7, a selective inhibitor targeting Janus Kinase 2 (JAK2), exhibits inhibitory concentrations (IC50) of 3 nM for JAK2, 11.7 nM for SET-2 cells, and 41 nM for Ba/F3 V617F cells, indicative of its potency and selectivity. This compound demonstrates more than 14-fold selectivity against JAK1, JAK3, and FLT3, underlining its specificity. JAK2-IN-7 effectively induces cell cycle arrest at the G0/G1 phase and promotes apoptosis in tumor cells, manifesting significant antitumor activities [1].
价 格：￥电议型 号：T35900产 地：中国大陆
