T15641K777

K777 is a potent, orally active and irreversible inhibitor of cysteine protease. K777 is a potent CYP3A4 inhibitor (IC50= 60 nM). K777 is also a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 irreversibly inhibits Cruzain, which is the major cysteine protease of Trypansoma cruzi, and cathepsins B and L. K777 targets cathepsin-mediated cell entry and wxibits a broad-spectrum antiviral activity. K777 inhibits EBOV and SARS-CoV pseudovirus entry with IC50 values of 0.87

价 格：￥电议型 号：T15641产 地：中国大陆

TN12955-O-Caffeoylshikimic acidinhibit,5 O Caffeoylshikimic acid,Inhibitor,5OCaffeoylshikimic acid

5-O-Caffeoylshikimic acid shows anti-oxidative activity; it also shows anti-inflammatory activity, the underlying mechanism was associated with downregulation of nuclear factor-κB.

价 格：￥电议型 号：TN1295产 地：中国大陆

PDK04236-METHYL-1H-INDOLE-2-CARBOXYLIC ACID6METHYL1HINDOLE2CARBOXYLICACID

价 格：￥电议型 号：PDK0423产 地：中国大陆

TQ0150LevcromakalimPotassium Channel,KcsA,Inhibitor,inhibit,BRL38227,BRL-38227,Levcromakalim

Levcromakalim is an activator of the ATP-sensitive K+ channel.

价 格：￥电议型 号：TQ0150产 地：中国大陆

T9192BIIB068ADME,inhibit,FcγR,Autoimmune,Bruton tyrosine kinase,TNFα,BIIB 068,ROS,Inhibitor,reversible,Bt

BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.

价 格：￥电议型 号：T9192产 地：中国大陆

TP1898HS024selective,melanocortin,intake,Inhibitor,Melanocortin Receptor,MC Receptor,HS-024,food,HS024,inh

Highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo.

价 格：￥电议型 号：TP1898产 地：中国大陆

TN2100PratenseinInhibitor,Nuclear factor-kappaB,Nuclear factor-κB,cognitive,inhibit,BDNF,synapse,Pratensei

Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.

价 格：￥电议型 号：TN2100产 地：中国大陆

T8796CAN508inhibit,CAN 508,ATP-competitive,Cyclin dependent kinase,esophageal,cells,CDK,CAN508,Inhibitor,

CAN508 is a potent, ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 μM. It is also a competitive inhibitor of Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 and 20 μM, respectively.CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. Antitumor activity.

价 格：￥电议型 号：T8796产 地：中国大陆

TQ0283RS102895CC chemokine receptor,CCR,Inhibitor,RS102895,inhibit,RS-102895,RS 102895

RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.

价 格：￥电议型 号：TQ0283产 地：中国大陆

T9041AES-350Histone deacetylases,AES 350,MV4-11,AES-350,Apoptosis,acute myeloid leukemia,AML,Inhibitor,in

AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, and >1μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.

价 格：￥电议型 号：T9041产 地：中国大陆

T61518TAK-653

TAK-653, an AMPA receptor potentiator with minimal agonistic activity, produces an antidepressant-like effect with a favorable safety profile in rats.

价 格：￥电议型 号：T61518产 地：中国大陆

T6924Riviciclib hydrochlorideinhibit,Inhibitor,Riviciclib,CDK,Riviciclib hydrochloride,Cyclin dependent k

P276-00 is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3.

价 格：￥电议型 号：T6924产 地：中国大陆

T39389KDM2B-IN-2KDM2B IN 2,KDM-2B-IN-2,KDM2BIN2

KDM2B-IN-2 is a potent histone demethylase (kdm2b) inhibitor.

价 格：￥电议型 号：T39389产 地：中国大陆

T6767TCS7010Aurora Kinase,inhibit,TCS 7010,Apoptosis,TCS-7010,TCS7010,Inhibitor

Aurora A Inhibitor I is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B.

价 格：￥电议型 号：T6767产 地：中国大陆

T6443Chloroprocaine hydrochlorideinhibit,Na,K-ATPase,Sodium potassium pump,Chloroprocaine,anesthetic,2-Ch

Chloroprocaine HCl is a local anesthetic during surgical procedures.

价 格：￥电议型 号：T6443产 地：中国大陆

T7974Lynestrenolinhibit,progesteronelike,Pregnane,Inhibitor,immunostimulatory,zfPXR,Lynestrenol,PXR,hPXR

Lynestrenol is a synthetic progestational hormone, is the progesterone receptor agonist

价 格：￥电议型 号：T7974产 地：中国大陆

T60072ZL0590non-KAc binding site,ZL0590,ZL-0590,BRD4 BD1,Inhibitor,acute airway inflammation,inhibit,Epige

ZL0590 is an effective and selective inhibitor of BD1-BRD4 (IC50 = 90 nM) with anti-inflammatory activities.

价 格：￥电议型 号：T60072产 地：中国大陆

T24240K-8012

K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.

价 格：￥电议型 号：T24240产 地：中国大陆

T9820GPI-1485neurofunctional,regeneration,Inhibitor,ligand,stroke,GPI-1485,GPI 1485,inhibit,immunophilin,

GPI-1485 (GM1485) is a nonimmunosuppressive immunophilin ligand, promoting neurofunctional improvement and neural regeneration following stroke.

价 格：￥电议型 号：T9820产 地：中国大陆

TQ0230BTK IN-1Btk,SNS062,Inhibitor,SNS-062,BTK IN 1,Bruton tyrosine kinase,SNS 062,inhibit,BTK IN-1,BTK IN

BTK IN-1 (SNS062 analog) is an effective BTK inhibitor (IC50: <100 nM).

价 格：￥电议型 号：TQ0230产 地：中国大陆