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T8418DCLK1-IN-1DCLK1 IN 1,signaling,PDAC,KRAS,cancer,low,ERK,Inhibitor,selective,DCLK1IN1,inhibit,DCLK-1-
DCLK1-IN-1 is a selective and in vivo-compatible chemical probe of the DCLK1 kinase domain .
价 格：￥电议型 号：T8418产 地：中国大陆
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T8659K-Ras-PDEδ-IN-1KRasPDEδIN1,PDEδ,cancer,pyrazolopyridazinone-based,inhibit,K Ras PDEδ IN 1,Inhibitor,
K-Ras-PDEδ-IN-1 is a potent inhibitor of competitive K-Ras-PDEδ.It binds to the farnesyl binding pocket of PDEδ(Kd of 8 nM).
价 格：￥电议型 号：T8659产 地：中国大陆
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T8684SotorasibAMG 510,Ras,KRAS,covalent,Sotorasib,regression,mutation,Inhibitor,G12C,anti-tumour,inhibit,
AMG-510 is a selective and orally bioavailable KRAS G12C covalent inhibitor.
价 格：￥电议型 号：T8684产 地：中国大陆
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T7414ARS-853ARS 853,ARS-853,KRAS,Apoptosis,cancer,mutant,state,inhibit,Inhibitor,inactive,Ras,selective,c
ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells
价 格：￥电议型 号：T7414产 地：中国大陆
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T9303MRTX1133KRAS,Ras,MRTX 1133,G12D,cells,active,wild-type,phosphorylation,mutant,MRTX1133,inactive,ERK,
MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D. MRTX1133 exhibits an estimated KD against KRAS G12D of 0.2 pM. MRTX1133 inhibits mutant KRAS-dependent signal transduction by preventing SOS1-catalyzed nucleotide exchange and/or formation of the KRAS G12D/GTP/RAF1 complex. MRTX1133 selectively inhibits KRAS G12D mutant tumor cells with no effect on KRAS wild-type. MRTX1133 exhibits single digit nanomolar activity in cellular assays and marked in vivo efficacy in tumor mode
价 格：￥电议型 号：T9303产 地：中国大陆
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T62228KRAS G12D inhibitor 14
KRAS G12D inhibitor 14 is an effective inhibitor of KRAS G12D, showing significant antitumor effect and tumor growth inhibition in CT26 tumor models.
价 格：￥电议型 号：T62228产 地：中国大陆
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T6555K-Ras(G12C) inhibitor 12Apoptosis,K-Ras(G-12C) inhibitor 12,inhibit,Inhibitor,Ras,KRas(G12C) inhibit
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).
价 格：￥电议型 号：T6555产 地：中国大陆
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T6556K-Ras(G12C) inhibitor 9K-Ras(G-12C) inhibitor 9,KRas(G12C) inhibitor 9,Ras,Inhibitor,K-Ras(G12C) inh
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).
价 格：￥电议型 号：T6556产 地：中国大陆
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T8756KRAS inhibitor-9non-small,proliferation,inhibit,KRAS inhibitor 9,KRAS inhibitor9,cytotoxicity,Apopto
KRAS inhibitor-9 is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSCLC cells with KRAS mutation but not normal lung cells
价 格：￥电议型 号：T8756产 地：中国大陆
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T8756KRAS inhibitor-9；化合物KRAS inhibitor-9DUN09716；DUN09716
KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSC-LC cells with KRAS mutation but not normal lung cells
价 格：￥电议型 号：T8756产 地：中国大陆
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T79814pan-KRAS-IN-3；化合物 pan-KRAS-IN-3pan-KRAS-IN-3
Pan-KRAS-IN-3 (Example 84) is a pan-KRAS inhibitor suitable for cancer research [1].
价 格：￥电议型 号：T79814产 地：中国大陆
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T79808KRAS G12C inhibitor 61；化合物 KRAS G12C inhibitor 61KRAS G12C inhibitor 61
KRAS G12C inhibitor 61 (Example 3) demonstrates potent activity by inhibiting phospho-ERK 1/2 in MIA PaCa-2 cells, reflected in an IC50 value of 9 nM. This inhibitor is applicable in the research of pancreatic, colorectal, and lung cancers [1].
价 格：￥电议型 号：T79808产 地：中国大陆
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T79800pan-KRAS-IN-2；化合物 pan-KRAS-IN-2pan-KRAS-IN-2
Pan-KRAS-IN-2 (compound 6) is a broad-spectrum KRAS inhibitor exhibiting potent activity with IC50 values of ≤10 nM against KRAS wild type and its mutants (G12D, G12C, G12V, G12S, G12A, Q61H), while showing significantly reduced inhibition, with an IC50 ＞10 μM, for the KRAS G13D mutant [1].
价 格：￥电议型 号：T79800产 地：中国大陆
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T79799pan-KRAS-IN-4；化合物 pan-KRAS-IN-4pan-KRAS-IN-4
Pan-KRAS-IN-4 (compound 5) is a potent KRAS inhibitor, demonstrating IC50 values of 0.37 nM for Kras G12C and 0.19 nM for Kras G12V [1].
价 格：￥电议型 号：T79799产 地：中国大陆
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T79166KRAS G12C inhibitor 60；化合物 KRAS G12C inhibitor 60KRAS G12C inhibitor 60
KRAS G12C Inhibitor 60 (compound 23), a selective inhibitor targeting the Kras-G12C mutation, is utilized in the investigation of lung, colorectal, and pancreatic cancers [1].
价 格：￥电议型 号：T79166产 地：中国大陆
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T79162SOS1/KRAS-IN-1；化合物 SOS1/KRAS-IN-1SOS1/KRAS-IN-1
SOS1/KRAS-IN-1 (Compound 2) serves as an inhibitor of SOS1/KRAS, with potential application in the study of diseases mediated by SOS1/KRAS [1].
价 格：￥电议型 号：T79162产 地：中国大陆
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T79150KRAS G12C inhibitor 59；化合物 KRAS G12C inhibitor 59KRAS G12C inhibitor 59
KRAS G12C Inhibitor 59 is a compound with anticancer properties.
价 格：￥电议型 号：T79150产 地：中国大陆
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T79148PROTAC KRAS G12C degrader-3；化合物 PROTAC KRAS G12C degrader-3PROTAC KRAS G12C degrader-3
PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized in cancer research [1].
价 格：￥电议型 号：T79148产 地：中国大陆
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T79147KRAS degrader-1；化合物 KRAS degrader-1KRAS degrader-1
KRAS degrader-1 (compound 1) is a potent agent that selectively targets KRAS proteins for destruction via the autophagy-lysosomal degradation pathway [1].
价 格：￥电议型 号：T79147产 地：中国大陆
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T79072KRAS G12D modulator-1；化合物 KRAS G12D modulator-1KRAS G12D modulator-1
KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging from 1-10 μM against NEA-G12D, PPI-G12D, and p ERK-AGS, and is utilized in cancer research [1].
价 格：￥电议型 号：T79072产 地：中国大陆
