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产品数:86101
参观次数:3498776
已选条件
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T9192BIIB068ADME,inhibit,FcγR,Autoimmune,Bruton tyrosine kinase,TNFα,BIIB 068,ROS,Inhibitor,reversible,Bt
BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.
价 格:¥电议型 号:T9192产 地:中国大陆
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T8796CAN508inhibit,CAN 508,ATP-competitive,Cyclin dependent kinase,esophageal,cells,CDK,CAN508,Inhibitor,
CAN508 is a potent, ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 μM. It is also a competitive inhibitor of Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 and 20 μM, respectively.CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. Antitumor activity.
价 格:¥电议型 号:T8796产 地:中国大陆
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T6767TCS7010Aurora Kinase,inhibit,TCS 7010,Apoptosis,TCS-7010,TCS7010,Inhibitor
Aurora A Inhibitor I is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B.
价 格:¥电议型 号:T6767产 地:中国大陆
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TQ0230BTK IN-1Btk,SNS062,Inhibitor,SNS-062,BTK IN 1,Bruton tyrosine kinase,SNS 062,inhibit,BTK IN-1,BTK IN
BTK IN-1 (SNS062 analog) is an effective BTK inhibitor (IC50: <100 nM).
价 格:¥电议型 号:TQ0230产 地:中国大陆
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T8402Regorafenib HydrochlorideRaf,PDGFR,Raf kinases,inhibit,Inhibitor,RET,Regorafenib Hydrochloride,Vascu
Regorafenib Hydrochloride is a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity
价 格:¥电议型 号:T8402产 地:中国大陆
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T9040Aurora kinase inhibitor-2inhibit,Aurora-A,Aurora kinase inhibitor2,Aurora Kinase,ATP-competitive,Aur
Aurora Kinase Inhibitor II is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).
价 格:¥电议型 号:T9040产 地:中国大陆
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T7123AMG-47aInhibitor,signal,kinases,AMG 47a,JAK,Janus kinase,AMG-47a,transduction,Src,VEGFR,cytoplamic,p
AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells.
价 格:¥电议型 号:T7123产 地:中国大陆
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T4074GSK-872translocation,GSK-872,neurological,HMGB1,Receptor-interacting protein kinases,brain,GSK 872,c
GSK872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM).
价 格:¥电议型 号:T4074产 地:中国大陆
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T9609GRK5-IN-2metabolic,bicyclic,insulin,kinase,inhibit,Inhibitor,disease,pyridine-based,GRK5 IN 2,GRK-5-
GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor. It regulates the expression and/or release of insulin and is useful for the metabolic disease research.
价 格:¥电议型 号:T9609产 地:中国大陆
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T6635EMD638683inhibit,EMD-638683,EMD638683,Serum and glucocorticoid-regulated kinase,EMD 638683,Inhibitor
EMD638683,a novel SGK inhibitor with antihypertensive potency(with an IC50 of 3 μM).
价 格:¥电议型 号:T6635产 地:中国大陆
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T7604ValrubicinInhibitor,AD 32,AD32,Valrubicin,inhibit,PKC,Antibiotic,Protein kinase C
Valrubicin (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.
价 格:¥电议型 号:T7604产 地:中国大陆
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TQ0187SR-3677Inhibitor,Rho-associated protein kinase,Autophagy,SR 3677,Rho-kinase,SR3677,ROCK,ROK,SR-3677,
SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).
价 格:¥电议型 号:TQ0187产 地:中国大陆
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T7015Vps34-IN-1inhibit,Autophagy,Vps34IN1,PI3K,Vps-34-IN-1,Inhibitor,Phosphoinositide 3-kinase,Vps34 IN 1
Vps34-IN1 is a potent and highly selective Vps34 inhibitor with IC50 of 25 nM invitro, which does not significantly inhibit the isoforms of class I as well as class II PI3Ks.
价 格:¥电议型 号:T7015产 地:中国大陆
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T6815HS-1371HS-1371,Inhibitor,Receptor-interacting protein kinases,RIPK,inhibit,HS 1371,RIP kinase,HS1371
HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.
价 格:¥电议型 号:T6815产 地:中国大陆
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T9095Necrostatin-34Necrostatin 34,RIP kinase,FADD,Necrostatin-34,RIPK,inhibit,RIPK1,Receptor-interacting
Necrostatin-34 is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.
价 格:¥电议型 号:T9095产 地:中国大陆
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T6883SamotolisibInhibitor,mTOR,LY-3023414,Phosphoinositide 3-kinase,DNA-dependent protein kinase,inhibit,
LY3023414 is an oral ATP competitive inhibitor of the class I PI3K isoforms, DNA-PK, and mTOR. LY3023414 has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, BREAST CANCER, and Advanced Cancer, among others.
价 格:¥电议型 号:T6883产 地:中国大陆
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T6068MK-5108MK 5108,VX689,Aurora Kinase,VX 689,inhibit,Autophagy,MK-5108,Inhibitor
MK-5108 is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.
价 格:¥电议型 号:T6068产 地:中国大陆
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T81526-DemethoxytangeretinCluster of differentiation 246,6Demethoxytangeretin,Anaplastic lymphoma kinase
6-Demethoxytangeretin is a citrus flavonoid isolated from Citrus depressa.
价 格:¥电议型 号:T8152产 地:中国大陆
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TP1053LProtein Kinase C 19-31 acetateProtein Kinase C 19 31 acetate,Protein Kinase C 1931 acetate
Protein Kinase C 19-31 acetate, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate peptide for testing the protein kinase C activity.
价 格:¥电议型 号:TP1053L产 地:中国大陆
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TN1968N-?Feruloyloctopaminecarcinoma,N-?Feruloyloctopamine,inhibit,Protein kinase B,MAPK,PKB,Inhibitor,Hep
N-Feruloyloctopamine is a natural product.
价 格:¥电议型 号:TN1968产 地:中国大陆