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T2315GSK-LSD1 dihydrochlorideGSK-LSD1 2HCl
GSK-LSD1 2HCl is a specificity irreversible LSD1 inhibitor (IC50: 16 nM). The selectivity of GSK-LSD1 for LSD1 is >1000 fold over other closely related FAD utilizing enzymes (i.e. MAO-A, LSD2, MAO-B).
价 格:¥电议型 号:T2315产 地:中国大陆
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T11882Pulrodemstat benzenesulfonateLSD1-IN-7 benzenesulfonate;CC-90011 benzenesulfonate
LSD1-IN-7 benzenesulfonate is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.
价 格:¥电议型 号:T11882产 地:中国大陆
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T11882LSD1-IN-7 benzenesulfoteLSD1-IN-7 benzenesulfote,LSD1-IN-7 benzenesulfonate,
LSD1-IN-7 benzenesulfonate is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.
价 格:¥电议型 号:T11882产 地:美洲
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T2315GSK-LSD1 dihydrochlorideGSK-LSD1 dihydrochloride,GSK-LSD1 2HCl,
GSK-LSD1 2HCl is a specificity irreversible LSD1 inhibitor (IC50: 16 nM). The selectivity of GSK-LSD1 for LSD1 is >1000 fold over other closely related FAD utilizing enzymes (i.e. MAO-A, LSD2, MAO-B).
价 格:¥电议型 号:T2315产 地:美洲
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T83966LSD1-IN-30;LSD1 抑制剂30LSD1-IN-30
LSD1-IN-30 is a lysine-specific demethylase 1 (LSD1) inhibitor with anticancer activity for the study of small cell lung cancer and acute myeloid leukemia.
价 格:¥电议型 号:T83966产 地:中国大陆
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T82254GSK-LSD1;化合物 GSK-LSD1GSK-LSD1
GSK-LSD1, an LSD1 inhibitor, decreases food consumption and body weight while enhancing insulin sensitivity and glycemic regulation in murine obesity models. Additionally, it mitigates non-alcoholic fatty liver disease (NAFLD) and suppresses cytokine release induced by SARS-CoV-2 in COVID-19 peripheral blood mononuclear cells (PBMCs). Furthermore, GSK-LSD1 inhibits the proliferation and spread of cancer [1] [2] [3].
价 格:¥电议型 号:T82254产 地:中国大陆
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T81913LSD;化合物 LSDLSD
LSD-phthalocyanine is a conjugated compound utilized in photoimmunology research [1].
价 格:¥电议型 号:T81913产 地:中国大陆
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T78888LSD1-UM-109;化合物 LSD1-UM-109LSD1-UM-109
LSD1-UM-109 is a highly potent and reversible inhibitor of LSD1, demonstrating an IC50 of 3.1 nM. This compound exhibits strong antiproliferative activity, inhibiting cell growth with IC50 values of 0.6 nM in the MV4;11 acute leukemia cell line and 1.1 nM in the H1417 small-cell lung cancer cell line [1].
价 格:¥电议型 号:T78888产 地:中国大陆
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T77635LSD1-IN-27;LSD1抑制剂27LSD1-IN-27
LSD1-IN-27 is a potent LSD1 inhibitor with an IC50 value of 13 nM.LSD1-IN-27 inhibited the stemness and migration of gastric cancer cells.LSD1-IN-27 inhibited the expression of PD-L1 in BGC-823 and MFC cells.LSD1-IN-27 potentiated the T-cell immune response against gastric cancer.
价 格:¥电议型 号:T77635产 地:中国大陆
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T74858LSD1-IN-26;化合物 LSD1-IN-26LSD1-IN-26
LSD1-IN-26 (compound 12u), a potent LSD1 inhibitor, exhibits an IC50 of 25.3 nM. It also demonstrates inhibition of MAO-A (IC50 = 1234.57 nM) and MAO-B (IC50 = 3819.27 nM), significantly inducing apoptosis in MGC-803 cells. This compound is applicable in gastric cancer research [1].
价 格:¥电议型 号:T74858产 地:中国大陆
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T74855LSD1-IN-25;化合物 LSD1-IN-25LSD1-IN-25
LSD1-IN-25 (Compound 9j) is a potent, selective, and orally active inhibitor of LSD1, exhibiting an IC50 of 46 nM (Ki = 30.3 nM) and capable of inducing apoptosis in cancer cells [1].
价 格:¥电议型 号:T74855产 地:中国大陆
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T67871LSD1-IN-24;LSD抑制剂24LSD1-IN-24
LSD1-IN-24 is a selective and potent LSD1 inhibitor with an IC50 value of 0.247 μM.LSD1-IN-24 induces PD-L1 expression and enhances the T cell killing response, and can be used in cancer-related diseases.
价 格:¥电议型 号:T67871产 地:中国大陆
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T63920LSD1-IN-19;化合物 LSD1-IN-19LSD1-IN-19
LSD1-IN-19 (compound 29) is a selective, potent, non-covalent inhibitor of LSD1 (Ki: 0.108 μM, KD: 0.068 μM). The 72h IC50 values were 0.17 and 0.40 μM, respectively.
价 格:¥电议型 号:T63920产 地:中国大陆
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T63716LSD1-IN-18;化合物 LSD1-IN-18LSD1-IN-18
LSD1-IN-18 is a potent, non-covalent, selective inhibitor of LSD1 (Ki:0.156 μM; KD: 0.075 μM).LSD1-IN-18 exhibited anti-proliferative effects in THP-1 leukemia cells and MDA-MB-231 breast cancer cells with IC50 (72 h) of 0.16 and 0.21 μM, respectively.
价 格:¥电议型 号:T63716产 地:中国大陆
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T63140LSD1-IN-20;LSD1抑制剂20LSD1-IN-20
Lsd1-in-20 is a potent dual inhibitor of LSD1/G9a with Ki values of 0.44 and 0.68 μM, respectively. LSD1-IN-20 showed antiproliferative activity against THP-1 leukemia cells and MDA-MB-231 breast cancer cells in vitro, with IC50 of 0.51 and 1.60 μM, respectively, at 72 h.
价 格:¥电议型 号:T63140产 地:中国大陆
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T62818LSD1/ER-IN-1;化合物 LSD1/ER-IN-1LSD1/ER-IN-1
LSD1/ER-IN-1 (compound 11g) is a potent inhibitor of ER and LSD1 that acts on LSD1 (IC50: 1.55 μM). LSD1/ER-IN-1 showed good anti-proliferative effect on MCF-7 breast cancer cells (IC50: 8.79 μM).
价 格:¥电议型 号:T62818产 地:中国大陆
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T62679LSD1-IN-13 hydrochloride;化合物 LSD1-IN-13 hydrochlorideLSD1-IN-13 hydrochloride
LSD1-IN-13 hydrochloride (compound 7e) is an orally active inhibitor of LSD1 (IC50: 24.43 nM). hydrochloride induces differentiation of AML (acute myeloid leukemia) cell lines.
价 格:¥电议型 号:T62679产 地:中国大陆
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T62674LSD1-IN-21;化合物 LSD1-IN-21LSD1-IN-21
LSD1-IN-21 is a potent, blood-brain barrier permeable LSD1 (lysine specific demethylase-1) inhibitor (IC50: 0.956 μM).LSD1-IN-21 significantly reduces the pro-inflammatory cytokine TNF-α and exhibits good anti-cancer and anti-inflammatory effects.
价 格:¥电议型 号:T62674产 地:中国大陆
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T62099LSD1-IN-13;化合物 LSD1-IN-13LSD1-IN-13
LSD1-IN-13 (compound 7e) is an orally active LSD1 inhibitor (IC50: 24.43 nM) that also activates CD86 expression (EC50: 470 nM).LSD1-IN-13 induces differentiation of AML (acute myeloid leukaemia) cell lines.
价 格:¥电议型 号:T62099产 地:中国大陆
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T61405LSD1-IN-14;化合物 LSD1-IN-14LSD1-IN-14
LSD1-IN-14, a powerful and specific inhibitor of LSD1 (with an IC50 value of 0.89 μM), effectively suppresses the growth of A549 and THP-1 cells and promotes the apoptosis of tumor cells [1].
价 格:¥电议型 号:T61405产 地:中国大陆