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T15818LY367385LY367385
LY367385 is a highly effective and selective mGluR1a antagonist. LY367385 has neuroprotective, anticonvulsant, and antiepileptic effects. Compared with > 100 μM for mGlu5a, LY367385 has an IC50 of 8.8 μM for inhibits of quisqualate-induced phosphoinositid
价 格:¥电议型 号:T15818产 地:美洲
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T60355LY367385 hydrochloride;化合物 LY367385 hydrochlorideLY367385 hydrochloride
LY367385 hydrochloride is a potent and selective mGluR1a antagonist with an IC50 value of 8.8 μM for inhibiting quisqualate-induced phosphoinositide (PI) hydrolysis, showing significantly higher selectivity compared to its >100 μM IC50 value for mGlu5a. This compound exhibits neuroprotective, anticonvulsant, and antiepileptic effects [1] [2].
价 格:¥电议型 号:T60355产 地:中国大陆
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T39406(±)-LY367385;(±)-LY367385(±)-LY367385;(±)-LY367385
(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist. LY367385 exhibits a high inhibitory activity against quisqualate-induced phosphoinositide (PI) hydrolysis, with an IC50 value of 8.8 μM. In contrast, its inhibitory activity against mGlu5a is greater than 100 μM.
价 格:¥电议型 号:T39406产 地:中国大陆
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T15818LY367385;化合物 T15818LY367385
LY367385 is a highly effective and selective mGluR1a antagonist. LY367385 has neuroprotective, anticonvulsant, and antiepileptic effects. Compared with > 100 μM for mGlu5a, LY367385 has an IC50 of 8.8 μM for inhibits of quisqualate-induced phosphoinositide (PI) hydrolysis.
价 格:¥电议型 号:T15818产 地:中国大陆