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T3256MMAFMonoMethyl auristatin F;一甲基澳瑞他汀 F
Monomethyl auristatin F, an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.
价 格:¥电议型 号:T3256产 地:中国大陆
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T16031McMMAFMaleimidocaproyl monomethylauristatin F
McMMAF is a protective group-conjugated MMAF. MMAF is a potent tubulin polymerization inhibitor.It is a MMAF derivative having a Maleimidocaproyl linker (MC linker), which is ready to conjugate to antibody or other proteins or biopolymers. Mafodotin is a
价 格:¥电议型 号:T16031产 地:中国大陆
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T12081MMAF-OMeMonomethyl auristatin F methyl ester
MMAF-OMe is an antitubulin agent which inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively. MMAF-Ome is also an ADC cytotoxin.
价 格:¥电议型 号:T12081产 地:中国大陆
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T12081MMAF-OMeMMAF-OMe,Monomethyl auristatin F methyl ester,
MMAF-OMe is an antitubulin agent,and inhibits several tumor cell lines.
价 格:¥电议型 号:T12081产 地:美洲
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T16121MMAF HydrochlorideMMAF Hydrochloride,Monomethylauristatin F Hydrochloride,
MMAF Hydrochloride is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF Hydrochloride is an effective tubulin polymerization inhibitor and is used as an antitumor compound.
价 格:¥电议型 号:T16121产 地:美洲
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T16122MMAF sodiumMMAF sodium,Monomethylauristatin F sodium,
MMAF sodium is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF sodium is an effective tubulin polymerization inhibitor and is used as an antitumor agent.
价 格:¥电议型 号:T16122产 地:美洲
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T83129Amidate-VC-PAB-MMAF;化合物 Amidate-VC-PAB-MMAFAmidate-VC-PAB-MMAF
Amidate-VC-PAB-MMAF, a cleavable ADC linker (Amidate-VC-PAB) combined with a potent tubulin polymerization inhibitor (MMAF), is utilized in the synthesis of antibody-drug conjugates (ADCs) to decrease off-target cytotoxicity[1].
价 格:¥电议型 号:T83129产 地:中国大陆
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T82382Fmoc-MMAF-OMe;化合物 Fmoc-MMAF-OMeFmoc-MMAF-OMe
Fmoc-MMAF-OMe is a tubulin polymerization inhibitor and anticancer agent featuring an Fmoc protecting group. Its active component, MMAF, serves as the cytotoxic (ADC Cytotoxin) element in conventional antibody-drug conjugates (ADCs) [1].
价 格:¥电议型 号:T82382产 地:中国大陆
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T81715N3-PEG3-VC-PAB-MMAF;化合物 N3-PEG3-VC-PAB-MMAFN3-PEG3-VC-PAB-MMAF
N3-PEG3-VC-PAB-MMAF (Comp T-88-5) is a drug-linker conjugate for antibody-drug conjugates (ADCs) that comprises the ADC linker N3-PEG3-VC-PAB and the microtubule-disrupting agent MMAF [1]. This click chemistry reagent boasts an Azide group enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC) with Alkyne-bearing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with compounds presenting DBCO or BCN groups.
价 格:¥电议型 号:T81715产 地:中国大陆
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T80883Val-Cit-PAB-MMAF;化合物 Val-Cit-PAB-MMAFVal-Cit-PAB-MMAF
Val-Cit-PAB-MMAF is an agent-linker conjugate utilized for antibody-drug conjugates (ADCs), consisting of the peptide linker Val-Cit-PAB and the potent tubulin polymerization inhibitor known as MMAF [1].
价 格:¥电议型 号:T80883产 地:中国大陆
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T77894Val-Cit-PAB-MMAF sodium;化合物 Val-Cit-PAB-MMAF sodiumVal-Cit-PAB-MMAF sodium
Val-Cit-PAB-MMAF sodium is an agent-linker conjugate used in antibody-drug conjugates (ADCs), consisting of the peptide linker Val-Cit-PAB and the cytotoxic agent monomethyl auristatin F (MMAF), which inhibits tubulin polymerization [1].
价 格:¥电议型 号:T77894产 地:中国大陆
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T77892Mal-PEG8-Val-Cit-PAB-MMAF;化合物 Mal-PEG8-Val-Cit-PAB-MMAFMal-PEG8-Val-Cit-PAB-MMAF
Mal-PEG8-Val-Cit-PAB-MMAF is a drug-linker conjugate utilized for antibody-drug conjugates (ADCs), comprising a cleavable linker system and the potent tubulin inhibitor monomethyl auristatin F (MMAF), aimed at targeted cancer therapy.
价 格:¥电议型 号:T77892产 地:中国大陆
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T74880Cys-McMMAF;化合物 Cys-McMMAFCys-McMMAF
Cys-McMMAF, the active compound liberated from AlMcMMAF—a humanized anti-5T4 A1 antibody connected to the microtubule-disrupting molecule MMAF through a maleimidocaproyl linker—demonstrates antitumor effectiveness in two mouse tumor models (H1975 and MDA-MB-361-DYT2) [1].
价 格:¥电议型 号:T74880产 地:中国大陆
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T74177Modified MMAF;化合物 Modified MMAFModified MMAF
Modified MMAF, a cytotoxin for antibody-drug conjugates (ADC), facilitates the synthesis of ADCs tailored for targeted cancer research [1].
价 格:¥电议型 号:T74177产 地:中国大陆
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T68592Mafosfamide sodium;化合物 Mafosfamide sodiumMafosfamide sodium
Mafosfamide sodium is a synthetic oxazaphosphorine derivative with antineoplastic properties. Mafosfamide sodium alkylates DNA, forming DNA cross-links and inhibiting DNA synthesis. Although closely related to cyclophosphamide, Mafosfamide sodium, unlike cyclophosphamide, does not require hepatic activation to generate its active metabolite 4-hydroxy-cyclophosphamide; accordingly, Mafosfamide sodium is potentially useful in the intrathecal treatment of neoplastic meningitis.
价 格:¥电议型 号:T68592产 地:中国大陆
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T39897DBCO-PEG4-MMAF;DBCO-PEG4-MMAFDBCO-PEG4-MMAF;DBCO-PEG4-MMAF
DBCO-PEG4-MMAF is an antibody-drug conjugate (ADC) component that exhibits potent antitumor activity. It combines the tubulin polymerization inhibitor MMAF with a cleavable linker, DBCO-PEG4, to target cancer cells effectively.
价 格:¥电议型 号:T39897产 地:中国大陆
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T39748DBCO-PEG4-Val-Cit-PAB-MMAF;DBCO-PEG4-Val-Cit-PAB-MMAFDBCO-PEG4-Val-Cit-PAB-MMAF;DBCO-PEG4-Val-Cit-PA
DBCO-PEG4-Val-Cit-PAB-MMAF is a chemical compound that comprises a cleavable 4 unit polyethylene glycol antibody-drug conjugate (ADC) linker known as DBCO-PEG4-Val-Cit-PAB, and a highly effective inhibitor of tubulin polymerization called MMAF. This compound serves as a valuable component in the synthesis of ADCs.
价 格:¥电议型 号:T39748产 地:中国大陆
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T39238DBM-MMAF;DBM-MMAFDBM-MMAF
DBM-MMAF is a drug-linker conjugate composed of a potent antitubulin agent MMAF and a linker DBM to make antibody drug conjugate (ADC).
价 格:¥电议型 号:T39238产 地:中国大陆
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T38830Modified MMAF-C5-COOH;Modified MMAF-C5-COOHModified MMAF-C5-COOH;Modified MMAF-C5-COOH
Modified MMAF-C5-COOH is a drug-linker conjugate for ADC.
价 格:¥电议型 号:T38830产 地:中国大陆
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T3256MMAF一甲基澳瑞他汀 F一甲基澳瑞他汀 F|||MonoMethyl auristatin F
MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.
价 格:¥电议型 号:T3256产 地:中国大陆