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T8369Adagrasibinhibit,GDP-bound,mutant,MIA PaCa-2,MRTX-849,Adagrasib,selective,Inhibitor,MRTX 849,inactiv
MRTX849 is a potent, selective and covalent KRASG12C inhibitor with potential antineoplastic activity. It selectively modifies mutant cysteine 12 in GDP-bound KRASG12C, and inhibits KRAS-dependent signaling.
价 格：￥电议型 号：T8369产 地：中国大陆
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T8369Adagrasib；化合物MRTX849MRTX849；MRTX849
Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib exhibits inhibitory activity against KRAS G12C mutant tumors.
价 格：￥电议型 号：T8369产 地：中国大陆
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T40190MRTX849 ethoxypropanoic acid；MRTX849 ethoxypropanoic acidMRTX849 ethoxypropanoic acid
MRTX849 ethoxypropanoic acid is a compound that contains a ligand for KRAS G12C and a PROTAC linker. It is commonly employed in the synthesis of PROTAC LC-2, which is a highly effective and innovative PROTAC. LC-2 has been proven to degrade endogenous KRAS G12C with remarkable potency, exhibiting DC50 values ranging from 0.25 to 0.76 μM.
价 格：￥电议型 号：T40190产 地：中国大陆
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T40189MRTX849 acid；MRTX849 acidMRTX849 acid；MRTX849 acid
MRTX849 acid, a derivative of MRTX849, is employed in the synthesis of PROTAC LC-2. LC-2, a potent and pioneering PROTAC, exhibits the ability to efficiently degrade endogenous KRAS G12C with DC50 values ranging between 0.25 and 0.76 μM.
价 格：￥电议型 号：T40189产 地：中国大陆
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T40156MRTX849 analog 24；MRTX849 analog 24MRTX849 analog 24；MRTX849 analog 24
MRTX849 analog 24 is an alkyne-containing click probe analogue of the MRTX849 inhibitor for KRAS G12C. It is specifically designed for studying the functionality of MRTX849.
价 格：￥电议型 号：T40156产 地：中国大陆
