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T9146ms48107Inhibitor,GPR68,GPCR,MS 48107,ms48107,brain-penetrant,BBB,inhibit,5-HT2B,MS-48107,bioavailabl
MS48107 is a potent and selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68). It is selective for GPR68 over the closely related proton GPCRs, neurotransmitter transporters, and hERG ion channels. It can readily cross the blood-brain barrier (BBB) in mice.
价 格:¥电议型 号:T9146产 地:中国大陆
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T21714BMS453Inhibitor,BMS453,retinoid,RAR/RXR,inhibit,BMS-453,BMS 189453,TGFβ,breast,RARβ,RARγ,Retinoid X
BMS453, a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin. BMS453 inhibits breast cell growth predominantly through the induction of active TGFβ.
价 格:¥电议型 号:T21714产 地:中国大陆
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T1854MS436
MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.
价 格:¥电议型 号:T1854产 地:中国大陆
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T16154MS417GTPL7512
MS417 is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weak selectivity at CBP BRD with IC50 of 32.7 μM.
价 格:¥电议型 号:T16154产 地:中国大陆
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T16153MS4078
MS4078 is an inhibitor and aplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 19?nM for binding affinity to ALK.
价 格:¥电议型 号:T16153产 地:中国大陆
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T16153MS4078MS4078
MS4078 is an anaplastic lymphoma kinase (ALK) PROTAC. It has a Kd of 19?nM for binding affinity to ALK.
价 格:¥电议型 号:T16153产 地:美洲
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T16154MS417MS417,GTPL7512,
MS417 is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weak selectivity at CBP BRD with IC50 of 32.7 μM.
价 格:¥电议型 号:T16154产 地:美洲
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T1854MS436MS436
MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.
价 格:¥电议型 号:T1854产 地:美洲
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T82378Folate-MS432;化合物 Folate-MS432Folate-MS432
Folate-MS432 is a PROTAC that degrades MEKs selectively in cancer cells via folate receptor-dependent pathways.
价 格:¥电议型 号:T82378产 地:中国大陆
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T73433MS47134;化合物 MS47134MS47134
MS47134, a selective and potent MRGPRX4 agonist, exhibits an EC50 of 149 nM and holds potential for researching pain, itch, and mast cell-mediated hypersensitivity.
价 格:¥电议型 号:T73433产 地:中国大陆
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T71346MS4;化合物 MS4MS4
MS4 is a novel glucocorticoid receptor (GR) agonist with anti-inflammatory activity and displaying reduced impact on islets.
价 格:¥电议型 号:T71346产 地:中国大陆
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T6203LSaxagliptin hydrochloride化合物 T6203LBMS477118|||Saxagliptin|||BMS 477118|||Saxagliptin HCl|||BMS-4771
Saxagliptin is a new oral hypoglycemic of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones and reducing fasting and postprandial glucose concentrations in a glucose-dependent manner in patients with type 2 diabetes mellitus.
价 格:¥电议型 号:T6203L产 地:中国大陆
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T40233(Iso)-MS4322;MS4322异构体(Iso)-YS43-22|||MS4322 (isomer)|||YS43-22 (isomer);(Iso)-YS43-22|||MS4322 (iso
(Iso)-MS4322 ((Iso)-YS43-22) is a selective and potent protein arginine methyltransferase 5 (PRMT5) degrader with potential anticancer activity that effectively reduces PRMT5 protein levels in MCF-7 cells and inhibits the growth of a wide range of cancer cells.
价 格:¥电议型 号:T40233产 地:中国大陆
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T30527BMS-488043;化合物BMS-488043CHEMBL238103|||UNII-MKS21EJ435|||BMS 043|||BMS488043|||BMS 488043;CHEMBL2381
BMS-488043 is a novel and unique oral small molecule HIV fusion inhibitor that inhibits the attachment of Human Immunodeficiency Virus type 1 (HIV-1) to CD4(+) lymphocytes.BMS-488043 is used for the treatment of immune disorders, infections, and genitourinary disorders, and can be used in the study of HIV infect
价 格:¥电议型 号:T30527产 地:中国大陆
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T30526BMS-480404;化合物 T30526BMS 480404|||BMS480404|||UNII-T78485CEYD;BMS 480404|||BMS480404|||UNII-T78485CE
BMS-480404 is an effective small molecule inhibitor, which can bind to human keratinocyte fatty acid-binding protein.
价 格:¥电议型 号:T30526产 地:中国大陆
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T30522BMS-422461;化合物 T30522BMS422461|||BMS 422461;BMS422461|||BMS 422461
BMS-422461 is a prodrug of the novel fluoro-substituted camptothecin analog, BMS-286309.
价 格:¥电议型 号:T30522产 地:中国大陆
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T28116MS453;化合物 T28116MS-453|||MS 453;MS-453|||MS 453
MS453 is a potent and selective SETD8 inhibitor with an IC50 value of 804 nM.
价 格:¥电议型 号:T28116产 地:中国大陆
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T26848BMS-433771 free base;化合物 T26848BMS-433771|||BMS 433771|||BMS433771;BMS-433771|||BMS 433771|||BMS4337
BMS-433771, a novel inhibitor of respiratory syncytial virus (RSV), binds the RSV F glycoprotein and inhibits membrane fusion.
价 格:¥电议型 号:T26848产 地:中国大陆
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T24503MS438;化合物 T24503MS-438|||MS 438;MS-438|||MS 438
MS438 is an effective agonist of the TSH receptor.
价 格:¥电议型 号:T24503产 地:中国大陆