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T1992MertansineDM1;Maytansinoid DM1
Mertansine refers to the thiol-containing maytansinoid, DM1 (N2´-deacetyl-N2´-(3-mercapto-1-oxopropyl)maytansine) attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker to create an a
价 格:¥电议型 号:T1992产 地:中国大陆
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T1992MertansineMertansine,Maytansinoid DM1,DM1
Mertansine refers to the thiol-containing maytansinoid, DM1 (N2’-deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker to create an a
价 格:¥电议型 号:T1992产 地:美洲
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T77874Maytansinoid B;化合物 Maytansinoid BMaytansinoid B
Maytansinoid B, an ADC cytotoxin, conjugates with antibodies to create antibody-drug conjugates (ADCs). This antimitotic agent binds to tubulin, inhibiting microtubule assembly, and induces G2/M arrest in the cell cycle, leading to apoptosis [1] [2].
价 格:¥电议型 号:T77874产 地:中国大陆
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T74975Zn-DPA-maytansinoid conjugate 1;化合物 Zn-DPA-maytansinoid conjugate 1Zn-DPA-maytansinoid conjugate 1
Zn-DPA-maytansinoid conjugate 1, a small molecule-based immune checkpoint-targeting maytansinoid conjugate, effectively induces sustained tumor growth regression and transforms the tumor microenvironment (TME) into an "inflamed hot tumor" [1].
价 格:¥电议型 号:T74975产 地:中国大陆
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T1992Mertansine;化合物MertansineDM1|||Maytansinoid DM1;DM1|||Maytansinoid DM1
Mertansine (DM1) refers to the thiol-containing maytansinoid, DM1 (N2´-deacetyl-N2´-(3-mercapto-1-oxopropyl)maytansine) attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker to create an antibody-drug conjugate or ADC. Experimental ADCs with the SPP-DM1 design include lorvotuzumab mertansine.
价 格:¥电议型 号:T1992产 地:中国大陆
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T13766Maytansinoid DM4;化合物 T13766Maytansinoid DM4
Maytansinoid DM4, a thiol-containing maytansine derivative, is a highly potent cytotoxic moiety utilized in ADC applications.
价 格:¥电议型 号:T13766产 地:中国大陆
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T11058DM3;化合物 T11058Maytansinoid DM3;Maytansinoid DM3
DM3 (Maytansinoid DM3) is a maytansine mimic containing disulfide or thiol groups and a tubulin inhibitor. It is the cytotoxic part of antibody-drug conjugates (ADCs) .
价 格:¥电议型 号:T11058产 地:中国大陆