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产品数:86101
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T6800CCF642calcium,Inhibitor,PDI,CCF642,apoptosis,isomerases,disulfide,myeloma,CCF-642,protein,multiple,r
CCF642 is a novel PDI-inhibiting compound with antimyeloma activity.
价 格:¥电议型 号:T6800产 地:中国大陆
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T6561Laquinimodinhibit,multiple sclerosis,relapsing remitting,carboxamide,Nuclear factor-kappaB,Apoptosis
Laquinimod is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral therapy.
价 格:¥电议型 号:T6561产 地:中国大陆
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T6312R547Glycogen synthase kinase 3,kinase,multiple,tumor,cyclin-dependent,R547,Apoptosis,Cyclin dependen
R547 is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1.
价 格:¥电议型 号:T6312产 地:中国大陆
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T9370dCBP-1Inhibitor,p300,multiple,CRBN,myeloma,cell,degrader,PROTACs,MYC,CBP,inhibit,dCBP 1,dCBP1,hetero
dCBP-1 is a chemical degrader of p300/CBP. dCBP-1 hijacks the E3 ubiquitin ligase CRBN for selective degradation of p300/CBP. Degradation of p300/CBP by dCBP-1 leads to effective multiple myeloma cell killing.
价 格:¥电议型 号:T9370产 地:中国大陆
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T41290MST-312EGCG,Telomerase,epigallocatechin,gallate,Inhibitor,multiple,tea,MST-312,derivative,cancer,MST
MST-312 is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM).
价 格:¥电议型 号:T41290产 地:中国大陆
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T6796CB-5083Inhibitor,inhibit,multiple,p97,VCP,solid,tumors,myeloma,AAA,ATPase,Cdc48,CB-5083
CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).
价 格:¥电议型 号:T6796产 地:中国大陆
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T12871Talmapimodcytotoxicity,multiple,inhibit,tumor,SCIO 469,SCIO469,cells,Hsp27,Inhibitor,phosphorylation
Talmapimod is an selective, orally active, and ATP-competitive p38α inhibitor with IC50 of 9 nM and 90 nM for p38α and p38β, respectively. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs.
价 格:¥电议型 号:T12871产 地:中国大陆
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T9745ElevenostatHistone deacetylases,Elevenostat,JB3-22,multiple myeloma,inhibit,HDAC11,Inhibitor,HDAC
Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235??M.
价 格:¥电议型 号:T9745产 地:中国大陆
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T8342BRD9876Kinesin,microtubule,Inhibitor,BRD9876,BMSC,multiple,myeloma,α4-α6,CD34,tyrosine,ATP,MM1S,G2/M
BRD9876 is a selective inhibitor of MM1S growth.
价 格:¥电议型 号:T8342产 地:中国大陆
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T9125Tolebrutinibmultiple,PRN 2246,SAR-442168,inhibit,Bruton tyrosine kinase,Tolebrutinib,sclerosis,Bruto
Tolebrutinib is a potent, selective, orally active and brain-penetrant Bruton tyrosine kinase (BTK) inhibitor(IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively). It exhibits efficacy in central nervous system immunity. Tolebrutinib can be used for the research of multiple sclerosis (MS).
价 格:¥电议型 号:T9125产 地:中国大陆
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T22774Leukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA)
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) is Elongation factor 1 subunit.eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 com
价 格:¥电议型 号:T22774L产 地:中国大陆
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T72013Epigenetic Multiple Ligand;化合物 Epigenetic Multiple LigandEpigenetic Multiple Ligand
Epigenetic Multiple Ligand is a cell-permeable inhibitor of substrate processing by several chromatin-associated enzymes, including SIRT1/2, H3/SET7, H3/p300/CBP, H4/RmtA, PABP1/CARM1, and H4/PRMT1. It acts by inducing either apoptosis or granulocytic differentiation.
价 格:¥电议型 号:T72013产 地:中国大陆
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T22774LEEF1A1 (387-394) (Multiple species) (TFA);EEF1A1 (387-394) (Multiple species) 三氟乙酸EEF1A1 (387-394)
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) is Elongation factor 1 subunit.eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in the brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in the brain, h
价 格:¥电议型 号:T22774L产 地:中国大陆
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T22774eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species];化合物 T22774e
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in the brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in the brain, heart, and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has
价 格:¥电议型 号:T22774产 地:中国大陆