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  • T9617RdRP-IN-2RdRP IN 2,RdRPIN2

    RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor. It significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 ?M.It also inhibits Feline coronavirus (FIPV) replication.

    价 格:¥电议型 号:T9617产 地:中国大陆

  • T8591RNase L-IN-2RNase L IN 2,RNase LIN2

    RNase L-IN-2 is an activator of RNase L with EC50 of 22 uM; shows broad-spectrum antiviral activity against diverse types of RNA viruses, including the human pathogen human parainfluenza virus type 3, with no cytotoxic at the effective concentrations.

    价 格:¥电议型 号:T8591产 地:中国大陆

  • T81293Retrocyclin-2;化合物 Retrocyclin-2Retrocyclin-2

    Retrocyclin-2 is an antimicrobial peptide effective against human immunodeficiency virus (HIV), influenza A, and herpes simplex virus (HSV) [1].

    价 格:¥电议型 号:T81293产 地:中国大陆

  • T81271RIOK2-IN-2;化合物 RIOK2-IN-2RIOK2-IN-2

    RIOK2-IN-2 (8) functions as an inhibitor of RIOK2, exhibiting IC50 values of 3.02 μM in MKN-1 cells and 5.34 μM in MOLT4 cells [1].

    价 格:¥电议型 号:T81271产 地:中国大陆

  • T79665RUNX-IN-2;化合物 RUNX-IN-2RUNX-IN-2

    RUNX-IN-2 (Compound Conjugate 3) covalently attaches to RUNX-binding sequences, preventing RUNX proteins from associating with their targets, thereby inhibiting cancer cell proliferation and inducing p53-dependent apoptosis. Furthermore, RUNX-IN-2 suppresses tumor development in PANC-1 xenograft mice and demonstrates notable alkylation efficiency and specificity [1].

    价 格:¥电议型 号:T79665产 地:中国大陆

  • T79217RSV L-protein-IN-2;化合物 RSV L-protein-IN-2RSV L-protein-IN-2

    RSV L-protein-IN-2 (Compound A), a noncompetitive inhibitor of the RSV polymerase (IC50: 4.5 μM), exhibits antiviral activity against long RSV strains (EC50: 1.3 μM) [1].

    价 格:¥电议型 号:T79217产 地:中国大陆

  • T78887ROS-IN-2;化合物 ROS-IN-2ROS-IN-2

    ROS-IN-2 (compound 85), a seco-lupane triterpenoid derivative, inhibits reactive oxygen species (ROS) production and shields mitochondria from oxidative damage by curtailing the generation of oxidative stressors. It has applications in myocardial ischemia/reperfusion (MI/R) injury research [1].

    价 格:¥电议型 号:T78887产 地:中国大陆

  • T74631RNA polymerase II-IN-2;化合物 RNA polymerase II-IN-2RNA polymerase II-IN-2

    RNA polymerase II-IN-2 (compound 20iii), a potent inhibitor of RNA polymerase II (Pol II) with a K i value of 9.5 nM, demonstrates cytotoxicity against cancer cells, exhibiting toxicity levels 2 and 5 times higher than α-amanitin in CHO and HEK293 cells, respectively [1].

    价 格:¥电议型 号:T74631产 地:中国大陆

  • T74572RIPK2-IN-2;化合物 RIPK2-IN-2RIPK2-IN-2

    RIPK2-IN-2 (example 25) is a RIP2 kinase PROTAC inhibitor that effectively blocks RIP2-dependent proinflammatory signaling and regulates RIP2 kinase activity in autoinflammatory diseases [1].

    价 格:¥电议型 号:T74572产 地:中国大陆

  • T63779RmlA-IN-2;化合物 RmlA-IN-2RmlA-IN-2

    RmlA-IN-2 is a potent inhibitor of 1-phosphoglucose thymidyltransferase (RmlA) (IC50: 0.303 μM).RmlA-IN-2 affects the monosaccharide l-rhamnose biosynthetic pathway and affects bacterial cell wall permeability.

    价 格:¥电议型 号:T63779产 地:中国大陆

  • T63748rel-MDM2/4-p53-IN-2;化合物 rel-MDM2/4-p53-IN-2rel-MDM2/4-p53-IN-2

    rel-MDM2/4-p53-IN-2 (2q) is a potent dual MDM2/MDM4 inhibitor and p53 activator that acts on both the MDM2-p53 complex (IC50: 70.7 nM) and the MDM4-p53 complex (IC50: 81.4 nM). rel-MDM2/4-p53-IN-2 is capable of regulating cell cycle, induce apoptosis, and exhibit anti-cancer effects.

    价 格:¥电议型 号:T63748产 地:中国大陆

  • T62569RIPK3-IN-2;化合物 RIPK3-IN-2RIPK3-IN-2

    RIPK3-IN-2 is a RIP3 inhibitor that can be used in studies of diseases caused by or associated with activated necrotic pathways.

    价 格:¥电议型 号:T62569产 地:中国大陆

  • T62462RORγt/DHODH-IN-2;化合物 RORγt/DHODH-IN-2RORγt/DHODH-IN-2

    RORγt/DHODH-IN-2 (compound 1) is a potent dual RORγt/DHODH inhibitor that can be used in the study of inflammatory bowel disease (IBD).

    价 格:¥电议型 号:T62462产 地:中国大陆

  • T61291RSV/IAV-IN-2;化合物 RSV/IAV-IN-2RSV/IAV-IN-2

    RSV/IAV-IN-2 (compound 14c) represents a powerful dual inhibitor of RSV/IAV, exhibiting lower cytotoxicity compared to the clinical drug Ribavirin. It holds promise for the research of RSV and/or IAV infections [1].

    价 格:¥电议型 号:T61291产 地:中国大陆

  • T60585RSK2-IN-2;化合物 RSK2-IN-2RSK2-IN-2

    RSK2-IN-2 (Compound 25) is a reversible covalent inhibitor of the RPS6KA3 ( RSK2 ) kinase which also inhibits MSK1, MSK2, and RSK3 [1].

    价 格:¥电议型 号:T60585产 地:中国大陆

  • T40114RSV-IN-2;RSV-IN-2RSV-IN-2

    RSV-IN-2 is a powerful compound that acts as a dual inhibitor of both wild-type and mutant respiratory syncytial virus (RSV) fusion proteins. It efficiently inhibits the activity of these proteins, with an EC50 value of 0.27 nM for the wild-type and 0.70 nM for the D486N-mutant protein.

    价 格:¥电议型 号:T40114产 地:中国大陆

  • T28506Rbin-2;化合物Rbin-2Rbin-2

    Rbin-2 is a cell-permeable, potent, selective and reversible inhibitor of Midasin (Mdn1).Rbin-2 directly targets the AAA+ ATPase Midasin and inhibits eukaryotic ribosome production, making it a potent probe for the study of eukaryotic ribosome assembly processes.

    价 格:¥电议型 号:T28506产 地:中国大陆

  • T12747ROCK2-IN-2;化合物ROCK2-IN-2ROCK2-IN-2

    ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM).

    价 格:¥电议型 号:T12747产 地:中国大陆

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