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  • T38225N-Arachidonoyl-3-hydroxy-γ-Aminobutyric Acid;N-Arachidonoyl-3-hydroxy-γ-Aminobutyric AcidN-Arachidon

    Several different arachidonoyl amino acids, including N-arachidonoyl-3-hydroxy-γ-aminobutyric acid (NAG-3H-ABA), have been isolated and characterized from bovine brain. The glycine congener was further characterized and found to suppress formalin-induced pain in rats. NAG-3H-ABA was also found in rat brain by LC-MS techniques, but has not been fully characterized to date. Most arachidonoyl amino acids are poor ligands for the CB1 receptor.

    价 格:¥电议型 号:T38225产 地:中国大陆

  • T37530Glycerophospho-N-Arachidonoyl Ethanolamine;Glycerophospho-N-Arachidonoyl EthanolamineGlycerophospho-

    N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities. The different types of NAE can be derived from glycerophospho-linked precursors by the activity of glycerophosphodiesterase 1 (GDE1). Glycerophospho-N-arachidonoyl ethanolamine is the precursor of arachidonoyl ethanolamide (AEA), also known as anandamide. AEA is an endogenous cannabinoid neurotransmitter that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. It inhibit

    价 格:¥电议型 号:T37530产 地:中国大陆

  • T37216N-Arachidonoyl-L-Alanine;N-Arachidonoyl-L-AlanineN-Arachidonoyl-L-Alanine

    Several different arachidonoyl amino acids, including N-arachidonoyl-L-alanine (NALA), have been isolated and characterized from bovine brain. The glycine congener (NAGly) was further characterized and found to suppress formalin-induced pain in rats. NALA may have activity at cannabinoid receptor and/or VR1, but has not been fully characterized to date.

    价 格:¥电议型 号:T37216产 地:中国大陆

  • T35918N-Arachidonoyl Taurine;N-Arachidonoyl TaurineN-Arachidonoyl Taurine

    N-Arachidonoyl taurine is an arachidonoyl amino acid. It is oxygenated by 12(S)- and 15(S)-lipoxygenase and is converted to 12-HETE-taurine (12-HETE-T) in murine resident peritoneal macrophages. N-Arachidonoyl taurine is an activator of the transient receptor potential vanilloid (TRPV) channels TRPV1 and TRPV4 (EC50s = 28 and 21 μM, respectively). It increases calcium flux in HIT-T15 pancreatic β-cells and INS-1 rat islet cells when used at a concentration of 10 μM and increases insulin secretio

    价 格:¥电议型 号:T35918产 地:中国大陆

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