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T5643NG25
NG25 is a potent dual TAK1 and MAP4K2 inhibitor, with IC50s of 149 nM and 21.7 nM, respectively.
价 格:¥电议型 号:T5643产 地:中国大陆
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T5643NG25NG25
NG25 is a potent dual TAK1 and MAP4K2 inhibitor, with IC50s of 149 nM and 21.7 nM, respectively.
价 格:¥电议型 号:T5643产 地:美洲
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T69898NG25 trihydrochloride;化合物 NG25 trihydrochlorideNG25 trihydrochloride
NG25 trihydrochloride is a type II kinase inhibitor that inhibits MAP4K2 and TAK1. It also inhibits the Src family kinases Src and LYN and Abl family kinases as well as CSK, FER, and p38α. NG 25 prevents TNF-α-induced IKKα/β phosphorylation and IκB-α degradation in L929 cells. It inhibits secretion of IFN-α and IFN-β induced by CpG type B and CL097, respectively. NG 25 decreases cell viability of HCT116KRASWT, and to a greater degree of HCT116KRASG13D, colorectal cancer cells in a concentration
价 格:¥电议型 号:T69898产 地:中国大陆
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T5643NG25;化合物NG25NG25
NG25 is a potent dual TAK1 and MAP4K2 inhibitor, with IC50s of 149 nM and 21.7 nM, respectively.
价 格:¥电议型 号:T5643产 地:中国大陆