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上海陶术生物科技有限公司 主营产品：生物试剂,实验服务等

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  • T6609NMS-E973NMS-E973,Leukemia,NMS E973,inhibit,HSP,Heat shock proteins,Adenocarcinoma,Hsp90α,ovary,colon

    NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.

    价 格：￥电议型 号：T6609产 地：中国大陆

  • T33513MSBNMSBN

    MSBN is a highly selective fluorescent probe for mercaptans that can selectively image mercaptans in living cells and specifically label protein mercaptans by switching on the signal to identify various reversible protein mercaptans modifications.

    价 格：￥电议型 号：T33513产 地：中国大陆

  • T12236NMS-859

    NMS-859 is an effective and covalent inhibitor of valosin-containing protein (VCP)/p97 with IC50s of 0.37 μM and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively.

    价 格：￥电议型 号：T12236产 地：中国大陆

  • T6247OnvansertibNMS-P937；NMS-1286937

    NMS-P937 (NMS1286937), an oral, specific Polo-like Kinase 1 (PLK1) inhibitor, is with IC50 of 2 nM. The specificity of NMS-P937 forPLK1 is 5000-fold higher over PLK2/PLK3.

    价 格：￥电议型 号：T6247产 地：中国大陆

  • T4472NMS-P118

    NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.

    价 格：￥电议型 号：T4472产 地：中国大陆

  • T3678EntrectinibRXDX-101；NMS-E628；恩曲替尼

    Entrectinib is an inhibitor of TrkA (IC50: 1.7 nM), TrkB (IC50: 0.1 nM), and TrkC (IC50: 0.1 nM), as well as anaplastic lymphoma kinase (ALK; IC50: 1.6 nM) and C-ros oncogene 1 (ROS1; IC50: 0.2 nM). Entrectinib blocks proliferation of ALK-dependent cell l

    价 格：￥电议型 号：T3678产 地：中国大陆

  • T1853NMS-873NMS 873

    NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.

    价 格：￥电议型 号：T1853产 地：中国大陆

  • T12237NMS-P715

    NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).

    价 格：￥电议型 号：T12237产 地：中国大陆

  • T12236NMS-859NMS-859

    NMS-859 is a potent and covalent inhibitor of VCP (p97)(IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively).

    价 格：￥电议型 号：T12236产 地：美洲

  • T12237NMS-P715NMS-P715

    NMS-P715 is a selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).

    价 格：￥电议型 号：T12237产 地：美洲

  • T1853NMS 873NMS 873

    NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.

    价 格：￥电议型 号：T1853产 地：美洲

  • T6247NMS-P937NMS-P937,NMS-1286937,

    NMS-P937 (NMS1286937), an oral, specific Polo-like Kinase 1 (PLK1) inhibitor, is with IC50 of 2 nM. The specificity of NMS-P937 forPLK1 is 5000-fold higher over PLK2/PLK3.

    价 格：￥电议型 号：T6247产 地：美洲

  • T70754NMS-P953；化合物 NMS-P953NMS-P953

    NMS-P953 is a JAK2 inhibitor, displaying significant tumor growth inhibition in SET-?2 xenograft tumor model. NMS-P953 has a mechanism of action confirmed in vivo by typical modulation of known biomarkers, and with a favorable pharmacokinetic and safety profile.

    价 格：￥电议型 号：T70754产 地：中国大陆

  • T6609NMS-E973；化合物NMS-E973NMS-E973

    NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.

    价 格：￥电议型 号：T6609产 地：中国大陆

  • T6247Onvansertib；化合物NMS-P937NMS-P937|||NMS-1286937；NMS-P937|||NMS-1286937

    Onvansertib (NMS-1286937), an oral, specific Polo-like Kinase 1 (PLK1) inhibitor, is with IC50 of 2 nM. The specificity of NMS-P937 forPLK1 is 5000-fold higher over PLK2/PLK3.

    价 格：￥电议型 号：T6247产 地：中国大陆

  • T4472NMS-P118；化合物NMS-P118NMS-P118

    NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.

    价 格：￥电议型 号：T4472产 地：中国大陆

  • T41158MS 39N；MS 39NMS 39N

    MS 39N is a negative control for MS 39. Binds EGFR without inducing degradation.

    价 格：￥电议型 号：T41158产 地：中国大陆

  • T41157MS 154N；MS 154NMS 154N

    MS 154N is a negative control for MS 154. The compound exhibits high binding-affinity for WT and L858R-mutant EGFR (Kdvalues are 3 and 4.3 nM, respectively), but does not significantly induce degradation of EGFR mutants.

    价 格：￥电议型 号：T41157产 地：中国大陆

  • T3678Entrectinib；恩曲替尼RXDX-101|||NMS-E628；RXDX-101|||恩曲替尼|||NMS-E628

    Entrectinib (RXDX-101) is an inhibitor of TrkA (IC50: 1.7 nM), TrkB (IC50: 0.1 nM), and TrkC (IC50: 0.1 nM), as well as anaplastic lymphoma kinase (ALK; IC50: 1.6 nM) and C-ros oncogene 1 (ROS1; IC50: 0.2 nM). Entrectinib blocks proliferation of ALK-dependent cell lines, including those with C1156Y or L1196M resistance mutations, and inhibits ALK‐dependent signaling. It has been shown to inhibit the growth of a non-small cell lung Y cell line bearing an EML4-ALK rearrangement. In mice bearing va

    价 格：￥电议型 号：T3678产 地：中国大陆

  • T33513MSBN；化合物MSBNMSBN

    MSBN is a highly selective fluorescent probe for mercaptans that can selectively image mercaptans in living cells and specifically label protein mercaptans by switching on the signal to identify various reversible protein mercaptans modifications.

    价 格：￥电议型 号：T33513产 地：中国大陆

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