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产品数:86101
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T8439Clobenpropit dihydrobromideApoptosis,inhibit,Clobenpropit dihydrobromide,histamine H3R,antagonist,in
Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)
价 格:¥电议型 号:T8439产 地:中国大陆
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TN12373-O-Methylgallic acidAnthocyanin,3 O Methylgallic acid,inhibit,3OMethylgallic acid,metabolite,anti-c
3,4-Dihydroxy-5-methoxybenzoic acid reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. 3,4-Dihydroxy-5-methoxybenzoic acid inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1 which are known to be activated in colorectal cancer.
价 格:¥电议型 号:TN1237产 地:中国大陆
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TP1789LMalantide acetate(86555-35-3 free base)Malantide acetate(86555 35 3 free base),Malantide acetate(865
Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide that is phosphorylated by PKA and is used to measure PKA activity in vitro.
价 格:¥电议型 号:TP1789L产 地:中国大陆
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TN1438beta-Amyrin acetateHMG-CoA,betaAmyrin acetate,LDL,Fungal,inhibit,Inhibitor,arthritic,hemolysis,antif
beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, and anti-hyperlipidemic activities.
价 格:¥电议型 号:TN1438产 地:中国大陆
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TP1898HS024selective,melanocortin,intake,Inhibitor,Melanocortin Receptor,MC Receptor,HS-024,food,HS024,inh
Highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo.
价 格:¥电议型 号:TP1898产 地:中国大陆
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T8796CAN508inhibit,CAN 508,ATP-competitive,Cyclin dependent kinase,esophageal,cells,CDK,CAN508,Inhibitor,
CAN508 is a potent, ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 μM. It is also a competitive inhibitor of Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 and 20 μM, respectively.CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. Antitumor activity.
价 格:¥电议型 号:T8796产 地:中国大陆
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T6924Riviciclib hydrochlorideinhibit,Inhibitor,Riviciclib,CDK,Riviciclib hydrochloride,Cyclin dependent k
P276-00 is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3.
价 格:¥电议型 号:T6924产 地:中国大陆
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T7596FirocoxibLPS,COX-2,fever,ML1785713,Cyclooxygenase,COX,inhibit,Firocoxib,Inhibitor,anti-inflammatory,
Firocoxib is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.
价 格:¥电议型 号:T7596产 地:中国大陆
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T6507Gabapentin hydrochlorideInhibitor,Gabapentin hydrochloride,Gabapentin,Calcium Channel,Ca channels,in
Gabapentin HCl is a GABA analogue, used to treat seizures and neuropathic pain.
价 格:¥电议型 号:T6507产 地:中国大陆
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T6874Lercanidipine hydrochlorideantihypertensive,Inhibitor,calcium,Lercanidipine,Lercanidipine hydrochlor
Lercanidipine is a calcium channel blocker of the dihydropyridine class.
价 格:¥电议型 号:T6874产 地:中国大陆
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T6683STF-62247renal,STF-62247,VHL,carcinoma,inhibit,cytotoxic,cell,RCC,Inhibitor,STF62247,intracytoplasmi
STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.
价 格:¥电议型 号:T6683产 地:中国大陆
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TN1118Tormentic aciddiabetes,transporter,glucose,Tormentic acid,phosphorylation,RAW 264.7,inhibit,Inhibito
Tormentic acid is a natural product. It has anticancer, anti-inflammatory, anti-atherogenic , anti-allodynic, and hepatoprotective properties,
价 格:¥电议型 号:TN1118产 地:中国大陆
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T9240sulfopinneuroblastoma,antiproliferative,PIN1-3,tumors,cancer,pancreatic,Inhibitor,sulfopin,inhibit,c
Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
价 格:¥电议型 号:T9240产 地:中国大陆
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TP2324ThymulinThymulin
Thymulin is a peptide hormone which is mainly produced by thymic epithelial cells and it has immune-modulatory and anti-inflammatory effects
价 格:¥电议型 号:TP2324产 地:中国大陆
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TN1019Beta-mangostinBeta mangostin,Bacterial,pathway,Apoptosis,carcinoma,migration,antibacterial,inhibit,c
Beta-Mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-Mangostin (β-Mangostin) present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. Beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic).
价 格:¥电议型 号:TN1019产 地:中国大陆
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T8383Cyclopentolate Hydrochloridepesticide,inhibit,cycloplegic,mAChR,antimuscarinic,practice,Cyclopentola
Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively.
价 格:¥电议型 号:T8383产 地:中国大陆
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T10889CRTh2 antagonist 2CRTh2 antagonist 2,CRTh-2 antagonist 2
CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.
价 格:¥电议型 号:T10889产 地:中国大陆
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T6476Dofetilidecardiovascular,potent,specific,class,antiarrhythmic,orally,Inhibitor,UK68789,UK-68789,Dofe
Dofetilide is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ikr. This antiarrhythmic agent prolongs cardiac action potential duration and effective refractory period due to delayed repolarization without affecting conduction velocity. This results in a normal sinus rhythm. Dofetilide is used in the treatment of atrial fibrillation and flutter.
价 格:¥电议型 号:T6476产 地:中国大陆
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T74747-NitroindazoleInhibitor,inhibit,7Nitroindazole,7 Nitroindazole,Nitric oxide synthases,7-Nitroindazo
7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.
价 格:¥电议型 号:T7474产 地:中国大陆
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T6S1010Allomatrinealkaloid,antinociceptive,κ-opioid,Allomatrine,receptors,inhibit,(+)-Allomatrine,Inhibitor
Allomatrine is a natural product from Sophora alopecuroides L. Allomatrine, when given i.c.v., may stimulate the descending dynorphinergic neuron, resulting in the stimulation of KORs in the spinal cord.
价 格:¥电议型 号:T6S1010产 地:中国大陆