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  • TN1969N-(p-Coumaroyl) serotoninVSMC,PDGFR,aortic wall,N (p Coumaroyl) serotonin,inhibit,anti-inflammatory,

    N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower. N-(p-Coumaroyl) serotonin has antioxidant, cardioprotective effects after ischemia and antitumor activity, it may be beneficial in improving vascular distensibility and in reducing cardiovascular risk.N-(p-Coumaroyl) Serotonin ameliorates atherosclerosis and distensibility of the aortic wall in vivo and is usually used for the atherosclerosis research

    价 格：￥电议型 号：TN1969产 地：中国大陆

  • T4641BranaplamLMI 070；NVS-SM1

    LMI070 (NVS-SM1) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.

    价 格：￥电议型 号：T4641产 地：中国大陆

  • T3506Nazartinib那扎替尼；NVS-816；EGF816

    Nazartinib (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro.

    价 格：￥电议型 号：T3506产 地：中国大陆

  • T16367NVS-PAK1-1

    NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).

    价 格：￥电议型 号：T16367产 地：中国大陆

  • T12277NVS-ZP7-4

    NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7).

    价 格：￥电议型 号：T12277产 地：中国大陆

  • T12277NVS-ZP7-4NVS-ZP7-4

    NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7).

    价 格：￥电议型 号：T12277产 地：美洲

  • T16367NVS-PAK1-1NVS-PAK1-1

    NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).

    价 格：￥电议型 号：T16367产 地：美洲

  • T4641LMI 070LMI 070,NVS-SM1,Branaplam

    LMI070 (NVS-SM1) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.

    价 格：￥电议型 号：T4641产 地：美洲

  • T73266NVS-MALT1；化合物 NVS-MALT1NVS-MALT1

    NVS-MALT1 is an allosteric inhibitor of MALT1 [1].

    价 格：￥电议型 号：T73266产 地：中国大陆

  • T62055NVS-BET-1；化合物 NVS-BET-1NVS-BET-1

    NVS-BET-1 is a BET bromodomain inhibitor. NVS-BET-1 can regulate keratinocyte plasticity.

    价 格：￥电议型 号：T62055产 地：中国大陆

  • T4641Branaplam；化合物LMI 070LMI 070|||NVS-SM1；LMI 070|||NVS-SM1

    Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.

    价 格：￥电议型 号：T4641产 地：中国大陆

  • T41166NVS PAK1 C；NVS PAK1 CNVS PAK1 C

    NVS PAK1 C is a negative control of NVS PAK1 1, a potent and selective PAK1 inhibitor.

    价 格：￥电议型 号：T41166产 地：中国大陆

  • T37151NVS-CECR2-1NVS-CECR2-1NVS-CECR2-1

    NVS-CECR2-1 is a potent inhibitor of CECR2 (cat eye syndrome chromosome region, candidate 2), a component of chromatin complexes that regulate gene expression controlling development. It binds CECR2 with high affinity (IC50 = 0.047 μM by Alpha screen, Kd = 0.80 μM by ITC). NVS-CECR2-1 demonstrates no crossreactivity in a panel of 48 bromodomains and has no major activity in kinase, protease, and receptor panels. It shows robust activity in cells by FRAP assay, due to its slow off-rate, and has n

    价 格：￥电议型 号：T37151产 地：中国大陆

  • T36315NVS-PI3-4；NVS-PI3-4NVS-PI3-4；NVS-PI3-4

    NVS-PI3-4 is a highly selective inhibitor of the enzyme PI3Kγ. It is specifically designed for use in scientific investigations related to allergies, inflammatory conditions, and cancerous diseases[1][2].

    价 格：￥电议型 号：T36315产 地：中国大陆

  • T35928NVS-PAK1-C；NVS-PAK1-CNVS-PAK1-C；NVS-PAK1-C

    NVS-PAK1-1 is a potent allosteric inhibitor of PAK1 with an IC 50 of 5 nM for dephosphorylated PAK1 and 6 nM for phosphorylated PAK1 as assessed. Inhibition is ATP-competitive, most likely due to indirect competition due to incompatibility of ATP binding with the DFG-out binding conformation of the allosteric compound. NVS-PAK1-1 has an IC50 of 270 nM against dephosphorylated PAK2 and 720 nM against phosphorylated PAK2 respectively [1].

    价 格：￥电议型 号：T35928产 地：中国大陆

  • T3506Nazartinib；那扎替尼EGF816|||NVS-816；那扎替尼|||EGF816|||NVS-816

    Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro.

    价 格：￥电议型 号：T3506产 地：中国大陆

  • T33764NVS-SM2；化合物 T33764NVS-SM2

    NVS-SM2 is an effective small molecule splicing enhancer of SMN2 with oral activity. NVS-SM2 showed increased exon 7 inclusion and upregulated SMN protein expression in SMA fibroblasts and SMN cells Δ7 5025 mouse myoblasts.

    价 格：￥电议型 号：T33764产 地：中国大陆

  • T16367NVS-PAK1-1；化合物NVS-PAK1-1NVS-PAK1-1

    NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).

    价 格：￥电议型 号：T16367产 地：中国大陆

  • T12634(R)-NVS-ZP7-4；化合物 T12634(R)-NVS-ZP7-4

    (R)-NVS-ZP7-4 is the R-isomer of NVS-ZP7-4. NVS-ZP7-4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor. NVS-ZP7-4 is the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel druggable node in the Notch pathway.

    价 格：￥电议型 号：T12634产 地：中国大陆

  • T12277NVS-ZP7-4；化合物NVS-ZP7-4NVS-ZP7-4

    NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7).

    价 格：￥电议型 号：T12277产 地：中国大陆

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