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T4376Nampt-IN-1LSN3154567
Nampt-IN-1 (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.
价 格：￥电议型 号：T4376产 地：中国大陆
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T12171Nampt-IN-5
Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .
价 格：￥电议型 号：T12171产 地：中国大陆
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T79437NAMPT degrader-3；化合物 NAMPT degrader-3NAMPT degrader-3
NAMPT Degrader-3 (compound C5) is a NAMPT degrader that functions through a VHL- and proteasome-dependent mechanism. It exhibits cytotoxic properties and inhibits the proliferation of A2780 cells [1].
价 格：￥电议型 号：T79437产 地：中国大陆
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T75023Nampt degrader-2；化合物 Nampt degrader-2Nampt degrader-2
Nampt degrader-2, a fluorescent PROTAC, exhibits efficient degradation of NAMPT at an IC50 of 41.9 nM. It operates by binding to both NAMPT and VHL, initiating the formation of a ternary complex that triggers NAMPT degradation through the ubiquitin-proteasome system (UPS). This activity significantly lowers NAD+ levels and displays potent antitumor effects [1].
价 格：￥电议型 号：T75023产 地：中国大陆
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T74615NAMPT degrader-1；化合物 NAMPT degrader-1NAMPT degrader-1
NAMPT Degrader-1 (Compound A3), a nicotinamide phosphoribosyltransferase (NAMPT) degrader, exhibits potent antitumor activity in cells by specifically inducing the degradation of NAMPT via the autophagy-lysosomal pathway, with an inhibitory concentration (IC50) of 0.023 μM [1].
价 格：￥电议型 号：T74615产 地：中国大陆
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T74562Nampt-IN-10 trihydrochloride；化合物 Nampt-IN-10 trihydrochlorideNampt-IN-10 trihydrochloride
Nampt-IN-10 trihydrochloride (Compound 4) is a Nicotinamide Phosphoribosyltransferase (NAMPT) inhibitor exhibiting cellular potency against A2780 and CORL23 cell lines, with IC50 values of 5 nM and 19 nM, respectively. It holds potential as a novel non-antimitotic payload for antibody-drug conjugate (ADC) [1].
价 格：￥电议型 号：T74562产 地：中国大陆
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T72623Nampt activator-3；化合物 Nampt activator-3Nampt activator-3
NAMPT Activator-3, a derivative of NAT, is a potent activator of NAMPT, demonstrating an EC50 of 2.6 μM and KD of 132 nM. It effectively shields cultured cells against toxicity induced by FK866 and has demonstrated significant neuroprotective effects in a chemotherapy-induced peripheral neuropathy (CIPN) mouse model, without any apparent toxicity [1].
价 格：￥电议型 号：T72623产 地：中国大陆
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T72617Nampt activator-2；Nampt激活剂2Nampt activator-2
Nampt activator-2 is a NAMPT activator (EC50: 0.023 μM). Nampt activator-2 has an affinity for CYP2C9, 2D6, and 2C19 with affinity values of 0.060 μM, 0.41 μM, and 0.59 μM, respectively.Nampt activator-2 can be used in the study of atherosclerosis, obesity, type II diabetes, insulin resistance, and type I diabetes.
价 格：￥电议型 号：T72617产 地：中国大陆
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T67925Nampt activator-1；化合物Nampt activator-1Nampt activator-1
NAMPT Activator-1 (compound 1) is an effective and specific activator of niacinamide phosphotransferase (Compound 1) with a wide range of EC50 (3.3-3.7 μM). NAMPT activator-1 effectively protects cultured cells from FK866-mediated toxicity and is a potential neuroprotective compound.
价 格：￥电议型 号：T67925产 地：中国大陆
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T64273Nampt-IN-10 TFA；化合物 Nampt-IN-10 TFANampt-IN-10 TFA
Nampt-IN-10 TFA (compound 4) is a phosphoribosyltransferase (NAMPT) inhibitor with cellular efficacy against A2780 (IC50: 5 nM) and CORL23 (IC50: 19 nM). The Nampt-IN-10 TFA can be used as a non-antimitotic payload for ADCs.
价 格：￥电议型 号：T64273产 地：中国大陆
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T64057Nampt-IN-8；化合物 Nampt-IN-8Nampt-IN-8
Nampt-IN-8 is a NAMPT inhibitor (IC50: 0.183 μM) and a good substrate for NQO1. Nampt-IN-8 induces reactive oxygen species (ROS) production and apoptosis.
价 格：￥电议型 号：T64057产 地：中国大陆
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T62748Nampt-IN-9；化合物 Nampt-IN-9Nampt-IN-9
Nampt-IN-9 (Compound 8) is a potent inhibitor of NAMPT with anticancer properties.Nampt-IN-9 can be used to study ductal adenocarcinoma of the pancreas.
价 格：￥电议型 号：T62748产 地：中国大陆
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T61597Nampt-IN-7；化合物 Nampt-IN-7Nampt-IN-7
Nampt-IN-7, also known as compound GF8, is a powerful NAMPT inhibitor exhibiting an IC50 value of 7.31 μM. It possesses significant cytotoxic effects against the human HepG2 hepatocellular carcinoma cell line, with an IC50 value of 24.28 μM [1].
价 格：￥电议型 号：T61597产 地：中国大陆
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T4376Nampt-IN-1；化合物Nampt-IN-1LSN3154567；LSN3154567
Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.
价 格：￥电议型 号：T4376产 地：中国大陆
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T18478NAMPT inhibitor-linker 2；化合物 T18478NAMPT inhibitor-linker 2
NAMPT inhibitor-linker 2, a drug-linker conjugate for antibody-drug conjugates (ADCs), comprises an NAMPT inhibitor payload and a linker. When combined with an anti-c-Kit monoclonal antibody to form ADC-4, it demonstrates potent efficacy against c-Kit expressing cell lines, including GIST-T1 and NCI-H526, with IC50 values of <7 pM and 40 pM, respectively.
价 格：￥电议型 号：T18478产 地：中国大陆
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T18477NAMPT inhibitor-linker 1；化合物 T18477NAMPT inhibitor-linker 1
NAMPT inhibitor-linker 1, a drug-linker conjugate for ADC, integrates an NAMPT inhibitor (as a payload) with a linker. In the formulation of ADC-3, it pairs with an anti-c-Kit monoclonal antibody, demonstrating strong efficacy against c-Kit expressing cell lines, specifically GIST-T1 and NCI-H526, where it exhibits IC50 values of <3 pM and 9 pM, respectively.
价 格：￥电议型 号：T18477产 地：中国大陆
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T13792Nampt-IN-3；化合物 T13792Nampt-IN-3
Nampt-IN-3 simultaneously inhibit nicotinamide phosphoribosyltransferase (NAMPT) and HDAC (IC50s of 31 nM and 55 nM, respectively).
价 格：￥电议型 号：T13792产 地：中国大陆
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T12171Nampt-IN-5；化合物Nampt-IN-5Nampt-IN-5
Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .
价 格：￥电议型 号：T12171产 地：中国大陆
