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T8381AmodiaquineCCL2,Nurr1,IL-1β,Histone Methyltransferase,Amodiaquine,Amodiaquin,inhibit,Inhibitor,anti-
Amodiaquine is a synthetic aminoquinoline, used to treat malaria.
价 格:¥电议型 号:T8381产 地:中国大陆
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T838944A7C-301-Nurr1 Agonist;化合物 4A7C-301-Nurr1 Agonist4A7C-301-Nuclear Receptor-Related 1;4A7C-301-Nuclea
The compound 4A7C-301-Nurr1 agonist is a specific agonist for the nuclear receptor-related 1 (Nurr1). By binding to the Nurr1 ligand-binding domain with an IC50 value of 48.22 nM, it enhances the transcriptional activity of both Nurr1-LBD and the full-length Nurr1, as demonstrated in reporter assays using SK-N-BE(2)C human neuroblastoma cells, with EC50 values of 6.53 and 50-70 ?M, respectively. Additionally, administration of 4A7C-301-Nurr1 agonist at a dosage of 5 mg/kg per day has been shown
价 格:¥电议型 号:T83894产 地:中国大陆
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T81635Nurr1 agonist 5;化合物 Nurr1 agonist 5Nurr1 agonist 5
Compound 5o, a Nurr1 agonist, exhibits neuroprotective properties as a transcription factor Nurr1 agonist, possessing a dissociation constant (Kd) of 0.5 μM and a half-maximal effective concentration (EC50) of 3 μM [1].
价 格:¥电议型 号:T81635产 地:中国大陆
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T81634Nurr1 agonist 6;化合物 Nurr1 agonist 6Nurr1 agonist 6
Compound 13, a Nurr1 agonist, exhibits a dissociation constant (Kd) of 1.5 μM and an effective concentration for 50% response (EC50) of 3 μM [1].
价 格:¥电议型 号:T81634产 地:中国大陆
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T81633Nurr1 agonist 7;化合物 Nurr1 agonist 7Nurr1 agonist 7
Nurr1 agonist 7 (compound 110) is an agonist targeting the Nurr1 receptor and exhibits an EC50 of 0.12 μM [1].
价 格:¥电议型 号:T81633产 地:中国大陆
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T81632Nurr1 agonist 8;化合物 Nurr1 agonist 8Nurr1 agonist 8
Compound 111 (Nurr1 agonist 8) is a Nurr1 agonist exhibiting an EC50 value of 0.09 μM [1].
价 格:¥电议型 号:T81632产 地:中国大陆
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T78088Nurr1 agonist 4;化合物 Nurr1 agonist 4Nurr1 agonist 4
Nurr1 agonist 4 (compound 8) serves as a potent Nurr1 agonist, exhibiting an EC50 value of 2.1 μM [1].
价 格:¥电议型 号:T78088产 地:中国大陆
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T77549Nurr1 agonist 2Nurr1激动剂2Nurr1agonist2|||Nurr1 agonist 2
Nurr1 agonist 2 is a Nurr1 agonist with an EC50 value of 0.07 μM. Nurr1 agonist 2 increases the mRNA expression of the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2). Nurr1 agonist 2 binds to the recombinant Nurr1 ligand-binding domain (LBD) with a Kd of 0.14 μM. Nurr1 agonist 2 can be used to study parkinsonism.
价 格:¥电议型 号:T77549产 地:中国大陆
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T60443Nurr1 agonist 1;化合物 Nurr1 agonist 1Nurr1 agonist 1
Nurr1 agonist 1 is an inverse agonist tool for the neuroprotective transcription factor Nurr1 which is an appealing target to treat neurodegenerative diseases.
价 格:¥电议型 号:T60443产 地:中国大陆