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TP1559LZiconotide Acetate (107452-89-1 free base)analgesic,non-opioid,Ziconotide Acetate (107452891 free
Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects.
价 格：￥电议型 号：TP1559L产 地：中国大陆
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T8439Clobenpropit dihydrobromideApoptosis,inhibit,Clobenpropit dihydrobromide,histamine H3R,antagonist,in
Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)
价 格：￥电议型 号：T8439产 地：中国大陆
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TP1881L1Pep 2-8 ammonium salt(1541011-97-5 free base)Pep 2 8 ammonium salt(1541011 97 5 free base),Pep 28 am
Pep 2-8 ammonium salt is Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.
价 格：￥电议型 号：TP1881L1产 地：中国大陆
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T16536Pimonidazole hydrochlorideinhibit,Pimonidazole hydrochloride,Pimonidazole,Inhibitor
Pimonidazole hydrochloride accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after the reduction of its nitro group. It can be used for qualitative and quantitative assessment of tumor hypoxia. Pimonidazole hydrochloride is a novel hypoxia marker for the complementary study of tumor hypoxia and cell proliferation in tumors.
价 格：￥电议型 号：T16536产 地：中国大陆
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T9192BIIB068ADME,inhibit,FcγR,Autoimmune,Bruton tyrosine kinase,TNFα,BIIB 068,ROS,Inhibitor,reversible,Bt
BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.
价 格：￥电议型 号：T9192产 地：中国大陆
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TN1768IriflophenoneInhibitor,MCF-7,proliferation,Iriflophenone,cells,T-47D,inhibit
Iriflophenone?stimulates cells proliferation in?MCF-7 and T-47D human breast cancer.
价 格：￥电议型 号：TN1768产 地：中国大陆
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TJS03384-Methylesculetininhibit,4 Methylesculetin,Glutathione Peroxidase,4-Methylesculetin,Inhibitor,4Methy
4-methylesculetin is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities.
价 格：￥电议型 号：TJS0338产 地：中国大陆
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TQ0015PRN1371inhibit,CSF1R,PRN 1371,Inhibitor,colony stimulating factor 1 receptor,c-Fms,CSF-1R,FGFR,CSF-1
PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).
价 格：￥电议型 号：TQ0015产 地：中国大陆
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T9041AES-350Histone deacetylases,AES 350,MV4-11,AES-350,Apoptosis,acute myeloid leukemia,AML,Inhibitor,in
AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, and >1μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.
价 格：￥电议型 号：T9041产 地：中国大陆
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T6908NSC 228155Epidermal growth factor receptor,Histone Acetyltransferase,EGFR,HER1,HATs,inhibit,Inhibito
NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
价 格：￥电议型 号：T6908产 地：中国大陆
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T14526Bemesetron
Bemesetron is a selective antagonist of 5-HT3 (IC50 = 0.33 nM) with neuroprotective effects.
价 格：￥电议型 号：T14526产 地：中国大陆
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T7083GLPG1837GLPG-1837,ABBV 974,Cystic fibrosis transmembrane conductance regulator,Inhibitor,CFTR,Autoph
GLPG1837 is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.
价 格：￥电议型 号：T7083产 地：中国大陆
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T7974Lynestrenolinhibit,progesteronelike,Pregnane,Inhibitor,immunostimulatory,zfPXR,Lynestrenol,PXR,hPXR
Lynestrenol is a synthetic progestational hormone, is the progesterone receptor agonist
价 格：￥电议型 号：T7974产 地：中国大陆
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TN6770Malabaricone AMalabaricone A
Malabaricone A is a bioactive chemical.
价 格：￥电议型 号：TN6770产 地：中国大陆
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T60072ZL0590non-KAc binding site,ZL0590,ZL-0590,BRD4 BD1,Inhibitor,acute airway inflammation,inhibit,Epige
ZL0590 is an effective and selective inhibitor of BD1-BRD4 (IC50 = 90 nM) with anti-inflammatory activities.
价 格：￥电议型 号：T60072产 地：中国大陆
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TN1118Tormentic aciddiabetes,transporter,glucose,Tormentic acid,phosphorylation,RAW 264.7,inhibit,Inhibito
Tormentic acid is a natural product. It has anticancer, anti-inflammatory, anti-atherogenic , anti-allodynic, and hepatoprotective properties,
价 格：￥电议型 号：TN1118产 地：中国大陆
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T9374AA38-3serine,ABHD6,Fatty acid amide hydrolase,AA38 3,Monoacylglycerol lipase,AA383,ABHD11,FAAH,MAGL,
AA38-3 inhibites three SHs (ABHD6, ABHD11, and FAAH)
价 格：￥电议型 号：T9374产 地：中国大陆
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T8070Nonadecanoic acidinhibit,Nonadecanoic acid,Inhibitor
Nonadecanoic acid is a long saturated fatty acid found in ox fats and vegetable oils, and in Staphylococcus. It can be used as a phermone by certain insects.
价 格：￥电议型 号：T8070产 地：中国大陆
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T8176NorflurazonNorflurazon
Norflurazon is an excellent weed controlling agent being practiced in the agricultural lands.
价 格：￥电议型 号：T8176产 地：中国大陆
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TN1019Beta-mangostinBeta mangostin,Bacterial,pathway,Apoptosis,carcinoma,migration,antibacterial,inhibit,c
Beta-Mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-Mangostin (β-Mangostin) present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. Beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic).
价 格：￥电议型 号：TN1019产 地：中国大陆
