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T8460OlmutinibOlmutinib
Olmutinib is a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
价 格：￥电议型 号：T8460产 地：中国大陆
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T6918OlmutinibOlmutinib,ErbB-1,inhibit,HER1,EGFR,Epidermal growth factor receptor,Inhibitor
Olmutinib is an orally available small molecule, a mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Olmutinib binds to and inhibits mutant forms of EGFR, thereby leading to cell death of EGFR-expressing tumor cells. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced as compared to non-selective EGFR inhibitors which also inhibit the EGFR wild-type form.
价 格：￥电议型 号：T6918产 地：中国大陆
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T8460Olmutinib；化合物OlmutinibHM61713|||BI1482694；HM61713|||BI1482694
Olmutinib (BI1482694) is a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
价 格：￥电议型 号：T8460产 地：中国大陆
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T70128Olmutinib hydrochloride；化合物 Olmutinib hydrochlorideOlmutinib hydrochloride
Olmutinib is a novel third-generation epidermal growth factor receptor (EGFR) mutation-specific tyrosine kinase inhibitor, used in the treatment of T790M mutation positive non-small cell lung cancer. Olmutinib covalently binds a cysteine residue near the kinase domain of mutant EGFRs to prevent phosphorylation of the receptor. EGFRs are frequently over-expressed in lung cancer and contribute to activation of the phosphoinositide 3-kinase and mitogen-activated protein kinase pathways which both p
价 格：￥电议型 号：T70128产 地：中国大陆
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T6918Olmutinib；奥莫替尼HM61713, BI 1482694|||BI 1482694|||HM61713；HM61713, BI 1482694|||奥莫替尼|||BI 1482694|||H
Olmutinib (HM61713, BI 1482694) is an orally available small molecule, a mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Olmutinib binds to and inhibits mutant forms of EGFR, thereby leading to cell death of EGFR-expressing tumor cells. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced as compared to non-selective EGFR inhibitors which also inhibit the EGFR wild-type form.
价 格：￥电议型 号：T6918产 地：中国大陆
