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T6750Opaganibinhibit,SphK,Opaganib,Sphingosine kinase,ABC-294640,Inhibitor,ABC 294640
ABC294640 is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).
价 格:¥电议型 号:T6750产 地:中国大陆
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T71301Opaganib HCl;化合物 Opaganib HClOpaganib HCl
ABC294640, also known as Opaganib, is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitively binds to and inhibits SK2, thereby preventing the phosphorylation of the pro-apoptotic amino alcohol sphingosine to sphingosine 1-phosphate (S1P), the lipid mediator that is pro-survival and critical for immunomodulation. This may eventually lead to the induction of apoptosis a
价 格:¥电议型 号:T71301产 地:中国大陆
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T6750Opaganib;化合物ABC294640ABC294640;ABC294640
Opaganib (ABC294640) is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).
价 格:¥电议型 号:T6750产 地:中国大陆