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T8703yGsy2p-IN-1diseases,synthase,hGYS1,pyrazole,GSDs,yGsy2p,yGsy2pIN1,yGsy-2p-IN-1,glycogen,storage,yGsy
yGsy2p-IN-1 is a potent yeast glycogen synthase 2 (yGsy2p) and human glycogen synthase 1 (hGYS1) inhibitor. yGsy2p-IN-H23 a pyrazole inhibitor,and is used for glycogen storage diseases (GSDs)
价 格:¥电议型 号:T8703产 地:中国大陆
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T10918NEP-IN-1NEP In 1,NEPIn1
NEP-IN-1 is an inhibitor of neutral endopeptidase (NEP, IC50 = 2 nM) and can be used in studies about female sexual arousal disorders.
价 格:¥电议型 号:T10918产 地:中国大陆
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T14283amyloid P-IN-1amyloid P IN 1,amyloid PIN1
amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer´s disease, amyloidosis, osteoarthritis, and type 2 diabetes mellitus.
价 格:¥电议型 号:T14283产 地:中国大陆
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T63293-Aminobenzamide3-AB;INO 1001;3-ABA;INO1001;INO-1001;PARP-IN-1
INO-1001 is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction during reperfusion.
价 格:¥电议型 号:T6329产 地:中国大陆
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T13230TXNIP-IN-1
TXNIP-IN-1 is an inhibitor of the TXNIP-TRX complex and used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease.
价 格:¥电议型 号:T13230产 地:中国大陆
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T10717InobrodibCBP-IN-1
CBP-IN-1 is a potent inhibitor of p300/CBP bromodomain.
价 格:¥电议型 号:T10717产 地:中国大陆
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T10717CBP-IN-1CBP-IN-1
CBP-IN-1 is a potent inhibitor of p300/CBP bromodomain.
价 格:¥电议型 号:T10717产 地:美洲
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T14283amyloid P-IN-1amyloid P-IN-1
amyloid P-IN-1 is used research of diseases or disorders wherein depletion of serum amyloid P component (SAP). Which including Alzheimer´s disease, amyloidosis, osteoarthritis, and type 2 diabetes mellitus.
价 格:¥电议型 号:T14283产 地:美洲
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T8706STAMBP-IN-1;化合物 STAMBP-IN-1STAMBP-IN-1
STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release after TLR agonism.
价 格:¥电议型 号:T8706产 地:中国大陆
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T8703yGsy2p-IN-1;化合物yGsy2p-IN-1yGsy2p-IN-1
yGsy2p-IN-1 is a potent yeast glycogen synthase 2 (yGsy2p) and human glycogen synthase 1 (hGYS1) inhibitor. yGsy2p-IN-H23 a pyrazole inhibitor,and is used for glycogen storage diseases (GSDs)
价 格:¥电议型 号:T8703产 地:中国大陆
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T81830MDM2/XIAP-IN-1;化合物 MDM2/XIAP-IN-1MDM2/XIAP-IN-1
MDM2/XIAP-IN-1 (compound 14) is an orally active dual inhibitor of MDM2 and XIAP, exhibiting anti-cancer activity with an IC50 of 0.3 μM and potential applications in cancer research [1].
价 格:¥电议型 号:T81830产 地:中国大陆
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T81792Mip-IN-1;化合物 Mip-IN-1Mip-IN-1
Mip-IN-1 (S,S-28i) is a novel inhibitor derived from rapamycin targeting the macrophage infectivity potentiator (Mip) proteins. It exhibits potent anti-enzymatic effects against Mip proteins from Neisseria meningitidis and Neisseria gonorrhoeae, significantly enhancing macrophage bactericidal efficacy [1].
价 格:¥电议型 号:T81792产 地:中国大陆
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T81595OSBP-IN-1;化合物 OSBP-IN-1OSBP-IN-1
OSBP-IN-1 (compound 12), an analogue of Schweinfurthins, selectively targets oxysterol-binding protein (OSBP) and exhibits antitumor activity [1].
价 格:¥电议型 号:T81595产 地:中国大陆
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T81548PAP-IN-1;化合物 PAP-IN-1PAP-IN-1
PAP-IN-1 (compound 28) is a binuclear metallohydrolase inhibitor specific to purple acid phosphatases (PAPs) with a Ki value of 168 nM against mammalian PAP and a Kic value of 0.17 μM targeting porcine PAP. This compound is significant in the research of anti-osteoporotic drug development [1].
价 格:¥电议型 号:T81548产 地:中国大陆
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T81311RASP-IN-1;化合物 RASP-IN-1RASP-IN-1
RASP-IN-1 (Compound A), a lipophilic compound, serves as an inhibitor for macular degeneration and exhibits biological activity within the rabbit retina. In a mouse model [1], the administration of 14 C-RASP-IN-1 (10 mg/kg) intraperitoneally yielded a maximum concentration (C max) of 14.36 μg/g in the posterior eye cup 30 minutes post-treatment.
价 格:¥电议型 号:T81311产 地:中国大陆
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T81181sEH/FLAP-IN-1;化合物 sEH/FLAP-IN-1sEH/FLAP-IN-1
sEH/FLAP-IN-1 (Compound 46A) serves as a dual inhibitor targeting both sEH and FLAP. It effectively suppresses 5-LOX product formation with an EC50 of 11 nM in SACM-stimulated PBMCs and also inhibits sEH activity (EC50: 18 nM) as well as thromboxane production. This compound is utilized in the study of inflammatory diseases [1].
价 格:¥电议型 号:T81181产 地:中国大陆
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T81105SREBP/SCAP-IN-1;化合物 SREBP/SCAP-IN-1SREBP/SCAP-IN-1
SREBP/SCAP-IN-1 (compound 10b) serves as a selective inhibitor of SREBP/SCAP [1].
价 格:¥电议型 号:T81105产 地:中国大陆
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T80870VE-PTP-IN-1;化合物 VE-PTP-IN-1VE-PTP-IN-1
VE-PTP-IN-1 (compound 2) is a selective inhibitor of the vascular endothelial protein tyrosine phosphatase (VE-PTP), possessing weakly acidic properties. It is associated with the regulation of vascular homeostasis and angiogenesis.
价 格:¥电议型 号:T80870产 地:中国大陆
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T79647VEGFR/PARP-IN-1;化合物 VEGFR/PARP-IN-1VEGFR/PARP-IN-1
VEGFR/PARP-IN-1 (Compound 14b) is a dual inhibitor of VEGFR and PARP with IC50 values of 191 nM and 60.9 nM, respectively. It impairs DNA damage repair pathways, promotes apoptosis, and halts cells in the G2/M phase. This compound demonstrates considerable antiproliferative activity against BRCA wild-type breast cancer cells, with IC50 values of 4.1 μM for MDA-MB-231 cells and 3.5 μM for MCF-7 cells, indicating its potential as an antitumor and anti-metastasis agent [1].
价 格:¥电议型 号:T79647产 地:中国大陆
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T79168CBP-IN-1;化合物 CBP-IN-1CBP-IN-1
CBP-IN-1 (compound 12) acts as a potent CBP inhibitor exhibiting an IC50 of 1.5 nM and additionally suppresses CBP BRET and BRD4(1) with IC50 values of 690 nM and 3100 nM, respectively [1].
价 格:¥电议型 号:T79168产 地:中国大陆