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  • T9617RdRP-IN-2RdRP IN 2,RdRPIN2

    RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor. It significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 ?M.It also inhibits Feline coronavirus (FIPV) replication.

    价 格：￥电议型 号：T9617产 地：中国大陆

  • T81547PAP-IN-2；化合物 PAP-IN-2PAP-IN-2

    Compound 35 (PAP-IN-2) is a purple acid phosphatase (PAP) inhibitor with an inhibition constant (Ki) of 186 nM, potentially useful in the development of anti-osteoporotic compounds [1].

    价 格：￥电议型 号：T81547产 地：中国大陆

  • T81104SREBP/SCAP-IN-2；化合物 SREBP/SCAP-IN-2SREBP/SCAP-IN-2

    SREBP/SCAP-IN-2 (compound 13) acts as a selective inhibitor of SREBP/SCAP [1].

    价 格：￥电议型 号：T81104产 地：中国大陆

  • T79917FAP-IN-2；化合物 FAP-IN-2FAP-IN-2

    FAP-IN-2 is a 99mTc-labeled, isonitrile-containing derivative of a fibroblast activation protein (FAPI) inhibitor suitable for tumor imaging [1].

    价 格：￥电议型 号：T79917产 地：中国大陆

  • T79353P-gp/BCRP-IN-2；化合物 P-gp/BCRP-IN-2P-gp/BCRP-IN-2

    P-gp/BCRP-IN-2 (compound 15), an oxadiazole derivative, functions as a dual inhibitor targeting both the ABC transporter P-glycoprotein (IC50: 1.6 nM) and BCRP (IC50: 600 nM). Additionally, it bolsters the anti-proliferative impact of Doxorubicin in the drug-resistant HT29/DX and MDCK-MDR1 human adenocarcinoma colon cancer cell lines [1].

    价 格：￥电议型 号：T79353产 地：中国大陆

  • T79012MDM2/XIAP-IN-2；化合物 MDM2/XIAP-IN-2MDM2/XIAP-IN-2

    MDM2/XIAP-IN-2 is a dual inhibitor targeting murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP). It promotes the degradation of MDM2 and impedes translation of XIAP mRNA, effectively inhibiting cancer cell proliferation. Notably, it exhibits potent activity against the acute lymphoblastic leukemia cell line EU-1, with an IC50 of 0.3 μM [1].

    价 格：￥电议型 号：T79012产 地：中国大陆

  • T78214FAP-IN-2 TFA；化合物 FAP-IN-2 TFAFAP-IN-2 TFA

    FAP-IN-2 TFA is a 99mTc-labeled, isonitrile-containing derivative inhibitor of fibroblast activation protein (FAP), utilized for tumor imaging [1].

    价 格：￥电议型 号：T78214产 地：中国大陆

  • T73921Ep300/CREBBP-IN-2；化合物 Ep300/CREBBP-IN-2Ep300/CREBBP-IN-2

    Ep300/CREBBP-IN-2 (Example 73), a powerful and orally bioavailable inhibitor targeting Ep300 and CREBBP, demonstrates IC50 values of 0.052 μM and 0.148 μM, respectively. This compound is employed in cancer research [1].

    价 格：￥电议型 号：T73921产 地：中国大陆

  • T73277FABP-IN-2；化合物 FABP-IN-2FABP-IN-2

    FABP-IN-2, a novel ligand for FABP3, demonstrates inhibition of both FABP3 and FABP4 with IC50 values of 1.16 μM and 4.27 μM, respectively.

    价 格：￥电议型 号：T73277产 地：中国大陆

  • T72719Tubulin/MMP-IN-2；化合物 Tubulin/MMP-IN-2Tubulin/MMP-IN-2

    Tubulin/MMP-IN-2, a dual inhibitor of tubulin and matrix metalloproteinases (MMPs), effectively inhibits tubulin polymerization and induces cell apoptosis. It demonstrates inhibitory activities against MMP-2, MMP-3, and MMP-9, with IC50 values of 24.95 μM, 31.60 μM, and 22.37 μM, respectively. This compound is utilized in cancer research.

    价 格：￥电议型 号：T72719产 地：中国大陆

  • T71195mPTP-IN-22；化合物 mPTP-IN-22mPTP-IN-22

    mPTP-IN-22 is a novel mitochondrial permeability transition pore (mptp) inhibitor

    价 格：￥电议型 号：T71195产 地：中国大陆

  • T62534POP-IN-2；化合物 POP-IN-2POP-IN-2

    POP-IN-2 (Compound 7k) is a potent, covalently bound inhibitor of prolyl oligopeptidase (POP) (Ki: 6 nM).POP-IN-2 can be used in neurodegenerative disease and cancer research.

    价 格：￥电议型 号：T62534产 地：中国大陆

  • T60682Elongation factor P-IN-2；化合物 Elongation factor P-IN-2Elongation factor P-IN-2

    Elongation factor P-IN-2 is a β-lysine derivative compound which is a potent elongation factor P (EFP) inhibitor. Elongation factor P-IN-2 affects the E. coli proliferation rates [1].

    价 格：￥电议型 号：T60682产 地：中国大陆

  • T25780MDK-4823；化合物 T25780LMPTP-IN-23|||LMPTP-IN 23|||MDK4823|||LMPTP-IN23|||MDK 4823；LMPTP-IN-23|||LMPTP-I

    MDK-4823, also known as LMPTP inhibitor1, is a potent low-molecular-weight tyrosine phosphatase (LMPTP) inhibitor. LMPTP is highly expressed in insulin-target tissues. LMPTP promotes diabetes and insulin resistance in obesity.

    价 格：￥电议型 号：T25780产 地：中国大陆

  • T15696NEP-IN-2；化合物 T15696NEP-IN-2

    NEP-IN-2 is an inhibitor of neutral endopeptidase. It also is used in the research of proliferation in atherosclerosis, restenosis.

    价 格：￥电议型 号：T15696产 地：中国大陆

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