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  • T67776PCSK9-IN-11PCSK9IN11

    PCSK9-IN-11 (compound 5r) is a potent PCSK9 inhibitor with oral activity. PCSK9-IN-11 shows inhibitory activity of PCSK9 transcription in HepG2 cells (IC50= 5.7 μM). PCSK9-IN-11 can increase LDL receptor (LDLR) protein level. PCSK9-IN-11 can be used for atherosclerosis research.

    价 格：￥电议型 号：T67776产 地：中国大陆

  • T81535PCSK9-IN-20；化合物 PCSK9-IN-20PCSK9-IN-20

    PCSK9-IN-20 (Compound 3i) is a PCSK9 inhibitor exhibiting an IC50 value of 3.96 ?M, shown to reduce PCSK9 and enhance LDLR protein levels in vitro [1].

    价 格：￥电议型 号：T81535产 地：中国大陆

  • T79239PCSK9-IN-19；化合物 PCSK9-IN-19PCSK9-IN-19

    PCSK9-IN-19 (Compound 1), a PCSK9 inhibitor, is utilized in researching the treatment of high LDL-cholesterol levels and the prevention of coronary artery disease [1].

    价 格：￥电议型 号：T79239产 地：中国大陆

  • T79053PCSK9-IN-17；化合物 PCSK9-IN-17PCSK9-IN-17

    PCSK9-IN-17 is a PCSK9 inhibitor utilized in the research of cholesterol metabolism.

    价 格：￥电议型 号：T79053产 地：中国大陆

  • T79052PCSK9-IN-16；化合物 PCSK9-IN-16PCSK9-IN-16

    PCSK9-IN-16, holds potential for research into hypercholesterolemia and other cardiovascular diseases [1].

    价 格：￥电议型 号：T79052产 地：中国大陆

  • T79051PCSK9-IN-15；化合物 PCSK9-IN-15PCSK9-IN-15

    PCSK9-IN-15 (compound 5) is a potent inhibitor of proprotein convertase subtilisin/kexin 9 (PCSK9, K D <200 nM) that plays a crucial role in cholesterol metabolism by regulating blood levels of low-density lipoprotein cholesterol (LDL-C). This compound is useful for researching cholesterol-lowering therapies and dyslipidemia [1].

    价 格：￥电议型 号：T79051产 地：中国大陆

  • T79030PCSK9-IN-14；化合物 PCSK9-IN-14PCSK9-IN-14

    PCSK9-IN-14, also known as compound Ia-8, is a potent inhibitor of PCSK9 [1].

    价 格：￥电议型 号：T79030产 地：中国大陆

  • T75545PCSK9-IN-9；化合物 PCSK9-IN-9PCSK9-IN-9

    PCSK9-IN-9, a natural isocoumarin, inhibits proprotein convertase subtilisin-kexin type 9 (PCSK9), IDOL, and SREBP2 mRNA expression, demonstrating specificity by inhibiting PCSK9 with an IC50 value of 11.9 μM [1].

    价 格：￥电议型 号：T75545产 地：中国大陆

  • T75147PCSK9-IN-18；化合物 PCSK9-IN-18PCSK9-IN-18

    PCSK9-IN-18 (compound 188) is a potent PCSK9 inhibitor with a K D value of <200 nM [1] .

    价 格：￥电议型 号：T75147产 地：中国大陆

  • T74167PCSK9-IN-3；化合物 PCSK9-IN-3PCSK9-IN-3

    PCSK9-IN-3 is a next-generation tricyclic peptide inhibitor of PCSK9, characterized by its novel structure, high potency, and oral bioavailability.

    价 格：￥电议型 号：T74167产 地：中国大陆

  • T73008PCSK9-IN-13；化合物 PCSK9-IN-13PCSK9-IN-13

    PCSK9-IN-13 is a potent inhibitor of PCSK9, effectively preventing the binding of PCSK9 to low-density lipoprotein (LDL) receptors through its mechanism of action. It exhibits this inhibitory activity with an IC 50 value of 537 nM.

    价 格：￥电议型 号：T73008产 地：中国大陆

  • T72025PCSK9-IN-10；化合物PCSK9-IN-10PCSK9-IN-10

    PCSK9-IN-10, a potent and orally active inhibitor of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9), exhibits a half-maximal inhibitory concentration (IC50) of 6.4 ?M. By enhancing the expression of Low-Density Lipoprotein Receptor (LDLR) protein and reducing PCSK9 expression, PCSK9-IN-10 effectively decreases atherosclerosis progression. This compound holds promise for hyperlipidemia research applications.

    价 格：￥电议型 号：T72025产 地：中国大陆

  • T67776PCSK9-IN-11；化合物PCSK9-IN-11PCSK9-IN-11

    PCSK9-IN-11 (compound 5r) is a potent PCSK9 inhibitor with oral activity. PCSK9-IN-11 shows inhibitory activity of PCSK9 transcription in HepG2 cells (IC50= 5.7 μM). PCSK9-IN-11 can increase LDL receptor (LDLR) protein level. PCSK9-IN-11 can be used for atherosclerosis research.

    价 格：￥电议型 号：T67776产 地：中国大陆

  • T64362AZD0780；化合物AZD0780PCSK9-IN-12|||EX-A6975；PCSK9-IN-12|||EX-A6975

    AZD0780 (EX-A6975) exhibits bind affinity for PCSK9 ( Kd ＜200 nM). AZD0780 has research value in cholesterol metabolism.

    价 格：￥电议型 号：T64362产 地：中国大陆

  • T60764PCSK9 modulator-4；化合物 PCSK9 modulator-4PCSK9 modulator-4

    PCSK9 modulator-4 (Compound 21) can be used in hyperlipidemia research that is a potent PCSK9 modulator (EC 50 = 0.15 nM). PCSK9 is a lowering low-density lipoprotein cholesterol (LDL-C) target that is recently validated [1].

    价 格：￥电议型 号：T60764产 地：中国大陆

  • T60646PCSK9 modulator-3；化合物 PCSK9 modulator-3PCSK9 modulator-3

    PCSK9 modulator-3 (Compound 13) is a potent PCSK9 modulator with an EC 50 value of 2.46 nM that has the potential in the hyperlipidemia research. PCSK9 is a recently proved target for lowering low-density lipoprotein cholesterol (LDL-C) [1].

    价 格：￥电议型 号：T60646产 地：中国大陆

  • T60541PCSK9 modulator-2；化合物 PCSK9 modulator-2PCSK9 modulator-2

    PCSK9 modulator-2 (Compound 1) is a potent PCSK9 modulator (EC 50 = 202 nM) that has the potential to be used in hyperlipidemia research. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a recently validated therapeutic target for lowering low-density lipoprotein cholesterol (LDL-C) [1].

    价 格：￥电议型 号：T60541产 地：中国大陆

  • T39685PCSK9 degrader 1；PCSK9 degrader 1PCSK9 degrader 1

    PCSK9 degrader 1 is a selective proprotein convertase substilisin-like/kexin type 9 (PCSK9) degrader. PCSK9 degrader 1 does not affect PCSK9 function.

    价 格：￥电议型 号：T39685产 地：中国大陆

  • T39528PCSK9-IN-2PCSK9-IN-2PCSK9-IN-2

    PCSK9-IN-2 is a newly developed small molecule that effectively inhibits the protein-protein interaction (PPI) between PCSK9 and LDLR. It has been found to have a potent inhibitory activity with an IC50 value of 7.57 μM.

    价 格：￥电议型 号：T39528产 地：中国大陆

  • T13813PCSK9 ligand 1；化合物 T13813PCSK9 ligand 1

    PCSK9 ligand 1 is a small molecule ligand for proprotein convertase substilisin-like/kexin type 9 (PCSK9) and shows high affinity to PCSK9(Ki of 107 nM).

    价 格：￥电议型 号：T13813产 地：中国大陆

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