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产品数:86101
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T8796CAN508inhibit,CAN 508,ATP-competitive,Cyclin dependent kinase,esophageal,cells,CDK,CAN508,Inhibitor,
CAN508 is a potent, ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 μM. It is also a competitive inhibitor of Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 and 20 μM, respectively.CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. Antitumor activity.
价 格:¥电议型 号:T8796产 地:中国大陆
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T9040Aurora kinase inhibitor-2inhibit,Aurora-A,Aurora kinase inhibitor2,Aurora Kinase,ATP-competitive,Aur
Aurora Kinase Inhibitor II is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).
价 格:¥电议型 号:T9040产 地:中国大陆
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TN1154NepetinInhibitor,Nepetin,inhibit
6-Methoxyluteolin has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain.
价 格:¥电议型 号:TN1154产 地:中国大陆
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T8580Bupranololnon-selective,competitive,Adrenergic Receptor,Bupranolol,Inhibitor,intrinsic,sympathomimet
Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.
价 格:¥电议型 号:T8580产 地:中国大陆
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T7558CID-1067700ML282,competitively,CID1067700,brain,Rab7,ML 282,GTPase,Ras,machinery,Ras-related,CID-106
CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases(Rab7 with a Ki of 13 nM).
价 格:¥电议型 号:T7558产 地:中国大陆
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T9214ELOVL6-IN-1ELOVL6IN1,noncompetitive,orally,palmitoyl-CoA,potent,malonyl-CoA,ELOVL-6-IN-1,Inhibitor,s
ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities, with an IC50 value of 0.350 μM. ELOVL6-IN-1 inhibits ELOVL6 in a noncompetitive manner for malonyl-CoA (Ki=994 nM) and palmitoyl-CoA[1].
价 格:¥电议型 号:T9214产 地:中国大陆
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T9409Mesdopetam hemitartrateDopamine Receptor,properties,neurotransmission,inhibit,stabilizing,disease,ps
Mesdopetam hemitartrate is an antagonist of dopamine D3 receptor (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor). It has psychomotor stabilizing properties.
价 格:¥电议型 号:T9409产 地:中国大陆
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T8637DMNBprecursor,Inhibitor,PET,DMNB,dopaminergic systems,inhibit
6-Nitroveratraldehyde is DNA-dependent protein kinase (DNA-PK) inhibitor with IC50 of 15 μM, an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair in human cells.
价 格:¥电议型 号:T8637产 地:中国大陆
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T6685Sulbactam sodiumcompetitive,Sulbactam,Antibiotic,bacteria,CP45899,Sulbactam sodium,complex,CP 45899,
Sulbactam sodium (Unasyn) is an irreversible β-lactamase inhibitor.
价 格:¥电议型 号:T6685产 地:中国大陆
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TQ0237LemborexantLemborexant,OX1R,Orexin Receptor (OX Receptor),CNS,competitive,inhibit,CYP3A4,E2006,Hypoc
Lemborexant is a reversible and orally active dual antagonist of the orexin OX1 and OX2 receptors (IC50s: 6.1 nM and 2.6 nM).
价 格:¥电议型 号:TQ0237产 地:中国大陆
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T8287Edpetilineinhibit,Edpetiline,Inhibitor
Edpetiline, a principal alkaloid from P. eduardi., has significant anti-inflammatory effects.
价 格:¥电议型 号:T8287产 地:中国大陆
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T8416Capmatinib xHClApoptosis,c-Met/HGFR,ATP competitive,inhibit,INC-280,Inhibitor,Capmatinib,SNU-5,INCB-
Capmatinib xHCl is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM).
价 格:¥电议型 号:T8416产 地:中国大陆
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T6893MK-886leukotriene,FLAP,5-LOX,5-LO activating protein,non-competitive,L-663536,L663536,keratin-1,Leuk
MK-886 is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.
价 格:¥电议型 号:T6893产 地:中国大陆
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TP1073Neuropeptide W-23(human)Neuropeptide W23(human),hypetension,anorexigenic effect,Neuropeptide W 23(hu
Neuropeptide W-23(human) is an endogenous ligand for NPBW1 and NPBW2.
价 格:¥电议型 号:TP1073产 地:中国大陆
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TN1120Osthenolinhibit,selective,Monoamine Oxidase,MAO,depression,competitive,Osthenol,Inhibitor,coumarin,O
Osthenol is a natural product, and is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 μM).It shows antitumor-promoting activity, it also has antifungal and antibacterial activities.
价 格:¥电议型 号:TN1120产 地:中国大陆
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T7673ATH686ATH686,inhibit,CD135,Inhibitor,Apoptosis,ATH-686,ATP-competitive,FLT3,antileukemic,Fms like ty
ATH 686 is an potent and selective Inhibitor of FLT3.
价 格:¥电议型 号:T7673产 地:中国大陆
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T8840PF-543 hydrochlorideNrf-2,PF543 hydrochloride,anti-cancer,sphingosine-competitive,S1P,Sphingosine Ki
PF-543 inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
价 格:¥电议型 号:T8840产 地:中国大陆
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T8987Epiblastin Ainduces reprogramming,ATP competitive,epiblast stem cells,inhibit,Casein Kinase,Inhibito
Epiblastin A is an inhibitor of Casein Kinase 1 (CK1). Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs).
价 格:¥电议型 号:T8987产 地:中国大陆
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T8825Capmatinib 2HCl.H2OS114,SNU-5,ATP competitive,Balb/c nu/nu mice,U-87MG,INCB-28060 dihydrochloride,or
Capmatinib 2HCl.H2O is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.
价 格:¥电议型 号:T8825产 地:中国大陆
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T7322TheliatinibATP-competitive,inhibit,EGFR,ERK,cancer,esophageal,Epidermal growth factor receptor,HMPL-
Theliatinib, a potent and highly selective EGFR inhibitor, with anti-tumor activity. Ki of 0.05 nM for wild type EGFR, and IC50s of 3 and 22 nM for EGFR and EGFR T790M/L858R mutant, respectively.
价 格:¥电议型 号:T7322产 地:中国大陆