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  • T70352PH11;化合物 PH11PH11

    PH11 is a novel Focal Adhesion Kinase (FAK) inhibitor. PH11 restores TRAIL apoptotic pathway in PANC-1 cells through down-regulation of c-FLIP via inhibition of FAK and the phosphatidylinositol-3 kinase (PI3K)/AKT pathways. Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) emerges as one of the most-promising experimental cancer therapeutic drugs and is currently being tested in clinical trials. However, both intrinsic and acquired resistance of human cancer cells to TRAIL

    价 格:¥电议型 号:T70352产 地:中国大陆

  • T28773SI-2;化合物SI-2SI2|||EPH 116|||EPH116|||EPH-116;SI2|||EPH 116|||EPH116|||EPH-116

    SI-2 is an inhibitor (SMI) of steroid receptor coactivator-3 (SRC-3 or AIB1). SI-2 can selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells, and selectively induce breast cancer cell death with IC50 values in the low nanomolar range (3-20 nM), but not affect normal cell viability.

    价 格:¥电议型 号:T28773产 地:中国大陆

  • T28408Phosphostim Sodium;化合物 T28408IPH1101|||Phosphostim|||IPH 1101|||IPH-1101;IPH1101|||Phosphostim|||IPH

    Phosphostim, a gamma9deta2 T lymphocytes agonist, is used potentially for the treatment of renal cell carcinoma, HCV infection.

    价 格:¥电议型 号:T28408产 地:中国大陆

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