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TP2334PMX 53 acetate(219639-75-5 free base)PMX 53 acetate(219639755 free base),PMX 53 acetate(219639 75 5
PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an agonist of Mas-related gene 2 (MrgX2).
价 格：￥电议型 号：TP2334产 地：中国大陆
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T12506L1PMX 205 acetate(514814-49-4 free base)
PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).
价 格：￥电议型 号：T12506L1产 地：中国大陆
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T83669PMX-53 TFA；化合物 PMX-53 TFAAcPhe-[Orn-Pro-D-Cyclohexylalanine-Trp-Arg]|||AcF-[OPdChaWR]|||3D53；AcPhe-[
PMX-53, a macrocyclic complement 5a (C5a) peptidomimetic and C5a receptor antagonist (IC50 = 0.3 ?M), effectively inhibits the C5a-induced secretion of myeloperoxidase (MPO) in isolated human polymorphonuclear leukocytes (PMNs). Administered orally at 10 mg/kg, PMX-53 mitigates vascular leakage, PMN infiltration, and the production of TNF-α and IL-6 in a rat peritoneal Arthus reaction model. Additionally, in a 3-nitropropionic acid (3-NP)-induced Huntington’s disease rat model, it alleviates bod
价 格：￥电议型 号：T83669产 地：中国大陆
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T73710PMX 205 Trifluoroacetate；化合物 PMX 205 TrifluoroacetatePMX 205 Trifluoroacetate
PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.
价 格：￥电议型 号：T73710产 地：中国大陆
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T38608Brilacidin tetrahydrochloride；Brilacidin tetrahydrochloridePMX 30063 tetrahydrochloride；PMX 30063 te
Brilacidin tetrahydrochloride (PMX 30063 tetrahydrochloride) is a defensin mimetic antibiotic compound, exhibiting potent anti-infective antimicrobial activity against a range of bacteria. It demonstrates MIC90 values of 1 μg/mL and 8 μg/mL against the Gram-positive bacteria Streptococcus pneumoniae and Streptococcus viridans, respectively. Additionally, it has a MIC90 value of 8 μg/mL for the Gram-negative bacteria Haemophilus influenzae and a MIC90 value of 4 μg/mL for Pseudomonas aeruginosa.
价 格：￥电议型 号：T38608产 地：中国大陆
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T38126PMX 53c；PMX 53cPMX 53c
Negative control for PMX 53. Active Analog also available.
价 格：￥电议型 号：T38126产 地：中国大陆
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T35836PMX-205 (trifluoroacetate salt)；PMX-205 (trifluoroacetate salt)PMX-205 (trifluoroacetate salt)
PMX-205 is a cyclic hexapeptide that acts as a potent antagonist of C5a receptor (C5aR; IC50= 31 nM).1It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma.2,3PMX-205 is also brain penetrant and reduces neuroinflammation and neurodegeneration in an animal model of Alzheimer´s disease.4
价 格：￥电议型 号：T35836产 地：中国大陆
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T31370Delparantag；化合物 T31370PMX60056|||PMX-60056|||PMX 60056；PMX60056|||PMX-60056|||PMX 60056
Delparantag( PMX-60056) is a heparins antidote designed to restore coagulation.
价 格：￥电议型 号：T31370产 地：中国大陆
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T28429PMX-53；化合物 T28429PMX53|||PMX 53；PMX53|||PMX 53
PMX-53 is a Mas-related gene 2 (MrgX2) agonist and C5aR(CD88) antagonist. PMX-53 reduces atherosclerotic lesions in a mouse model of atherosclerosis, inhibits lung metastasis in a mouse breast cancer model, inhibits C5a-induced hypernociception in rats.
价 格：￥电议型 号：T28429产 地：中国大陆
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T23166PMX 464；化合物 T23166PMX 464
inhibitor of the thioredoxin-thioredoxin reductase (Trx-TrxR) system
价 格：￥电议型 号：T23166产 地：中国大陆
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T14781Brilacidin；化合物 T14781PMX 30063；PMX 30063
Brilacidin is a nonpeptidic anti-infective in a new class of defensin mimetics used for the research of eye infections.
价 格：￥电议型 号：T14781产 地：中国大陆
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T12506L1PMX 205 acetate(514814-49-4 free base)；化合物PMX 205 acetatePMX 205 acetate(514814-49-4 free base)
PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).
价 格：￥电议型 号：T12506L1产 地：中国大陆
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T12506LPMX 205；化合物 T12506LPMX 205
PMX 205 is an effective complement antagonist of the C5a receptor.
价 格：￥电议型 号：T12506L产 地：中国大陆
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T12506PMX 205 Trifluoroacetate (514814-49-4 free base)；化合物 T12506PMX 205 Trifluoroacetate；PMX 205 Trifluor
PMX 205 Trifluoroacetate is a potent complement antagonist of C5a receptor.
价 格：￥电议型 号：T12506产 地：中国大陆
