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产品数：86101
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T8784IGS-1.76NCS-1,Ric8a,IGS 1.76,PPI,inhibit,IGS1.76,IGS-1.76,Inhibitor
IGS-1.76 shows a significantly increased affinity for hNCS-1 and is able to modulate the hNCS-1/Ric8a interaction efficiently.IGS-1.76 efficiently inhibits the human NCS-1/Ric8a complex.
价 格：￥电议型 号：T8784产 地：中国大陆
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T8873BractoppinDNA break,Bractoppin,phosphopeptide,inhibit,DNA/RNA Synthesis,DNA damage,RAD51,G2 arrest,I
Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activity exploration suggests that Bractoppin engages BRCA1 tBRCT residues recognizing pSer in the consensus motif, pSer-Pro-Thr-Phe, plus an abutting hydrophobic pocket that is distinct in structurally related BRCT domains, conferring selectivity.
价 格：￥电议型 号：T8873产 地：中国大陆
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T9044SORT-PGRN interaction inhibitor 1inhibit,PPI,Inhibitor,sortilin,SORTPGRN interaction inhibitor 1,pro
SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM).
价 格：￥电议型 号：T9044产 地：中国大陆
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T6889MI-136PPI,MI 136,Apoptosis,inhibit,MI136,Inhibitor,CRPC,castration,cancer,resistant,MI-136,Androgen
MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.
价 格：￥电议型 号：T6889产 地：中国大陆
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T8421TED-347PPI,irreversible,protein-protein,YAP,allosteric,TEAD4?Yap1,transcriptional,glioblastoma,TED 3
TED-347 is an irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.
价 格：￥电议型 号：T8421产 地：中国大陆
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T9039HIV-1 Nef-IN-1antiviral,HIV 1 Nef IN 1,SH3,HIV1 NefIN1,HIV,PPI,Nef,Inhibitor,inhibit,HIV-1,Human imm
HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM).
价 格：￥电议型 号：T9039产 地：中国大陆
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T8216T-1101 tosylateTAI95,T1101 tosylate,TAI-95,T1101,Apoptosis,Inhibitor,inhibit,T 1101,T-1101,PPI,TAI 9
T-1101 tosylate is an inhibitor of Hec1/Nek2, with antitumor activity.
价 格：￥电议型 号：T8216产 地：中国大陆
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T7387Ceftaroline fosamilN-phosphono,PPI 0903,inhibit,TAK599,MRSA,TAK 599,PPI-0903,T-91825,Bacterial,Inhib
Ceftaroline fosamil is a cephalosporin, with activity against Gram-positive pathogens.
价 格：￥电议型 号：T7387产 地：中国大陆
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T78444-IPPInhibitor,osteoclastogenesis,4IPP,MIF,4-IPP,inhibit,4 IPP,RANKL,osteoblast
4-IPP is an irreversible inhibitor of macrophage migration inhibitory factor (MIF)
价 格：￥电议型 号：T7844产 地：中国大陆
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T22135PPIase-Parvulin Inhibitor
PPIase-Parvulin Inhibitor is a cell-pemeable inhibitor of the Pin1 and Pin4.
价 格：￥电议型 号：T22135产 地：中国大陆
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T16421p-MPPI hydrochloride
p-MPPI hydrochloride is a selective antagonist of 5-HT1A receptor, and has antidepressant and anxiolytic-like effects.
价 格：￥电议型 号：T16421产 地：中国大陆
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T1192Protoporphyrin IX原卟啉；原卟啉IX；PPIX
Protoporphyrin IX is a tetrapyrrole containing 4 methyl, 2 propionic and 2 vinyl side chains that is a metabolic precursor for hemes, cytochrome c, and chlorophyll.
价 格：￥电议型 号：T1192产 地：中国大陆
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T10217LAbarelix阿巴瑞克；R3827；PPI 149
Abarelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist, which is used for prostate cancer treatment.
价 格：￥电议型 号：T10217L产 地：中国大陆
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T1192Protoporphyrin IXProtoporphyrin IX,PPIX,
Protoporphyrin IX is a tetrapyrrole containing 4 methyl, 2 propionic and 2 vinyl side chains that is a metabolic precursor for hemes, cytochrome c, and chlorophyll.
价 格：￥电议型 号：T1192产 地：美洲
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T16421p-MPPI hydrochloridep-MPPI hydrochloride
p-MPPI hydrochloride can cross the blood-brain barrier and has clear antidepressant and anxiolytic-like effects. p-MPPI hydrochloride is a selective 5-HT1A receptor antagonist. It has a high affinity for 5-HT1A receptors.
价 格：￥电议型 号：T16421产 地：美洲
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T82758CDK9-Cyclin T1 PPI-IN-1；化合物 CDK9-Cyclin T1 PPI-IN-1CDK9-Cyclin T1 PPI-IN-1
CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective inhibitor of the CDK9-Cyclin T1 protein-protein interaction (PPI), suppressing cell proliferation in TNBC MDA-MB-231 cells with an IC50 of 0.044 μM and inducing apoptosis. This compound diminishes CDK9 transcriptional activity and downregulates phosphorylation of RNA Pol II CTD ser2. In vivo, CDK9-Cyclin T1 PPI-IN-1 effectively impedes tumor growth in a TNBC 4T1 mouse model [1].
价 格：￥电议型 号：T82758产 地：中国大陆
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T8214Kushenol E；苦参醇EFlemiphilippinin D；苦参醇E|||Flemiphilippinin D
Kushenol E (Flemiphilippinin D) is a class of flavonoids isolated from Sophora flavescens. It is a non-competitive IDO1 inhibitor (IC50: 7.7 μM, Ki: 9.5 μM), has anti-tumor activity.
价 格：￥电议型 号：T8214产 地：中国大陆
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T81503PEX5-PEX14 PPI-IN-2；化合物 PEX5-PEX14 PPI-IN-2PEX5-PEX14 PPI-IN-2
Compound 12, also known as PEX5-PEX14 PPI-IN-2, is a PEX14-PEX5 protein-protein interaction (PPI) inhibitor with half-maximal effective concentration (EC50) values of 5 ?M in T. b. brucei and 17 ?M in HepG2 cells. It is utilized in the study of diseases associated with trypanosome infection [1].
价 格：￥电议型 号：T81503产 地：中国大陆
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T79457PEX5-PEX14 PPI-IN-1；化合物 PEX5-PEX14 PPI-IN-1PEX5-PEX14 PPI-IN-1
PEX5-PEX14 PPI-IN-1 (Compound 8) is a PEX14-PEX5 protein-protein interaction (PPI) inhibitor that disrupts the interaction between PEX5 and TbPEX14 with an inhibitory constant (Ki) of 53 μM. It effectively inhibits the bloodstream form of Trypanosoma brucei brucei, with a half-maximal effective concentration (EC50) of 5 μM [1].
价 格：￥电议型 号：T79457产 地：中国大陆
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T75791-BCP；化合物1-BCPPiperonylic acid piperidide；Piperonylic acid piperidide
1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents.
价 格：￥电议型 号：T7579产 地：中国大陆
