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T21694(R)-LisofyllinePentoxifylline,Inhibitor,STAT,anti-inflammatory,inhibit,STAT4,lysophosphatidic,(R)Lis
(R)-Lisofylline is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 ?M). (R)-Lisofylline interrupts IL-12 signaling-mediated STAT4 activation and can be used in studies about the treatment of type 1 diabetes and autoimmune disorders.
价 格:¥电议型 号:T21694产 地:中国大陆
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T216541-Oleoyl lysophosphatidic acid sodium1-Oleoyl lysophosphatidic acid sodium salt
1-Oleoyl lysophosphatidic acid sodium salt is an Endogenous agonist of LPA1 and LPA2
价 格:¥电议型 号:T21654产 地:中国大陆
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T838791-Arachidoyl Lysophosphatidic Acid sodium;化合物 1-Arachidoyl Lysophosphatidic Acid sodium1-Arachidoyl
1-Arachidoyl lysophosphatidic acid (1-arachidoyl LPA), a glycerophospholipid with arachidic acid at the sn-1 position, functions as an agonist for lysophosphatidic acid receptor 1 (LPA1). It effectively induces calcium mobilization in primary human lung fibroblasts at an EC50 value of 3.6 ?M, given these cells inherently express LPA1 but lack expression of LPA2-LPA6 receptors. Additionally, at a concentration of 2.5 ?M, 1-arachidoyl LPA binds to the ligand-binding domain of peroxisome proliferat
价 格:¥电议型 号:T83879产 地:中国大陆
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T837721-Linoleoyl Lysophosphatidic Acid sodium;化合物 1-Linoleoyl Lysophosphatidic Acid sodium1-Linoleoyl-2-h
1-Linoleoyl lysophosphatidic acid (1-linoleoyl LPA), a glycerophospholipid with linoleic acid at its sn-1 position, acts as an LPA2 receptor agonist and is the predominant LPA form in both mouse and human plasma. This compound preferentially boosts intracellular calcium in Sf9 cells expressing the LPA2 receptor (EC50 = ~10 nM), compared to those with LPA1 and LPA3 receptors (EC50s = ~200 and ~80 nM, respectively). Notably, 1-linoleoyl LPA serum concentrations are elevated in mice with NCTC clone
价 格:¥电议型 号:T83772产 地:中国大陆
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T77789Oleoyl-L-alpha-lysophosphatidic acid sodium salt;化合物 Oleoyl-L-alpha-lysophosphatidic acid sodium sal
Oleoyl-L-alpha-lysophosphatidic acid sodium salt is an essential cell membrane biosynthetic metabolite that mediates signal transduction by interacting with G protein-coupled receptors (GPCRs) (ie, LPA receptors). It is the receptor of LPA1 and LPA2. endogenous agonist.
价 格:¥电议型 号:T77789产 地:中国大陆
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T670731,2-Distearoyl-sn-glycero-3-phosphatidic acid (Na+ salt);化合物 1,2-Distearoyl-sn-glycero-3-phosphatidi
1,2-Distearoyl-sn-glycero-3-phosphatidic acid (Na+ salt) is a useful organic compound for research related to life sciences and the catalog number is T67073.
价 格:¥电议型 号:T67073产 地:中国大陆
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T37691Phosphatidic Acids (egg) (ammonium salt);Phosphatidic Acids (egg) (ammonium salt)Phosphatidic Acids
Phosphatidic acid is a phospholipid and an intermediate in glycerolipid biosynthesis. It is a transient intermediate in the synthesis of various phospholipid species that is synthesized de novo in cells via multiple routes, including the glycerol-3 phosphate and dihydroxyacetone phosphate pathways, enzymatic conversion of phosphatidylcholine by phospholipase D, and acetylation of lysophosphatidic acid by lysoPA-acyltransferase, among others. It has roles in shaping cellular membranes, cellular
价 格:¥电议型 号:T37691产 地:中国大陆
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T372831-Palmitoyl Lysophosphatidic Acid (sodium salt);1-Palmitoyl Lysophosphatidic Acid (sodium salt)1-Pal
1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of five different G protein-coupled receptors (GPCRs) to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. In addition to playing a role in the aforementioned biological responses, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, pipe
价 格:¥电议型 号:T37283产 地:中国大陆
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T372821-Palmitoyl Lysophosphatidic Acid;1-棕榈酰溶血磷脂酸1-Palmitoyl Lysophosphatidic Acid
1-Palmitoyl Lysophosphatidic Acid is an analog of LPA and improves the the action of ampicillin, piperacillin, and ceftazidime on various strains of P. aeruginosa via binding both Ca2+ and Mg2+.
价 格:¥电议型 号:T37282产 地:中国大陆
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T369071-Oleoyl Lysophosphatidic Acid;1-Oleoyl Lysophosphatidic AcidOleoyl-sn-3-Glycerophosphate|||1-Oleoyl
1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) followed by phosphorylation of DAG by diglycerol kinase.[1] Hydrolysis of the fatty acid at the sn-2 position by phospholipase A2 (PLA2) yields bioactive LPA. LPA binds to one of five differe
价 格:¥电议型 号:T36907产 地:中国大陆
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T367681-Octadecyl Lysophosphatidic Acid;1-Octadecyl Lysophosphatidic Acid1-Octadecyl Lysophosphatidic Acid
1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA recepto
价 格:¥电议型 号:T36768产 地:中国大陆
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T364521-Arachidonoyl Lysophosphatidic Acid (ammonium salt);1-Arachidonoyl Lysophosphatidic Acid (ammonium
1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol . 1-Arachidonoyl lysophosphatidic acid binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM. It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS. It also decreases differe
价 格:¥电议型 号:T36452产 地:中国大陆
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T33076Lysophosphatidic acid;化合物 T33076Lysophosphatidic acid
Lysophosphatidic acid is a bioactive chemical.
价 格:¥电议型 号:T33076产 地:中国大陆
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T216541-Oleoyl lysophosphatidic acid sodium;化合物T216541-Oleoyl lysophosphatidic acid sodium salt;1-Oleoyl l
1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2
价 格:¥电议型 号:T21654产 地:中国大陆