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T16563LPozanicline hydrochloride
Pozanicline hydrochloride is an orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist with a Ki of 16.7 nM for binding to [3H]cytisine sites[1]. Pozanicline hydrochloride is an α4β2-selective nAChR agonist, which binds to rat brain α4β2 nAC
价 格:¥电议型 号:T16563L产 地:中国大陆
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T12525Pozanicline dihydrochloridePozanicline dihydrochloride,ABT-089 dihydrochloride,
Pozanicline dihydrochloride is an orally bioavailable agonist of nicotinic acetylcholine receptor (nAChR) (Ki of 16.7 nM)
价 格:¥电议型 号:T12525产 地:美洲
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T16563LPozanicline hydrochloride;化合物Pozanicline hydrochloridePozanicline hydrochloride
Pozanicline hydrochloride is an orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist with a Ki of 16.7 nM for binding to [3H]cytisine sites[1]. Pozanicline hydrochloride is an α4β2-selective nAChR agonist, which binds to rat brain α4β2 nAChR with a Ki of 17 nM while binding to α7 nAChR is insignificant[2].
价 格:¥电议型 号:T16563L产 地:中国大陆
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T16563Pozanicline;化合物 T16563ABT-089;ABT-089
Pozanicline reverses nicotine withdrawal-induced cognitive deficits, may be an effective component of novel therapeutic strategies for nicotine addiction. Pozanicline selectively activate neuronal nicotinic acetylcholine receptor (nAChR) subtypes, is a novel cholinergic agent that is a partial agonist at α4β2 nAChRs (Ki=16 nM). It shows high selectivity for α6β2 and α4α5β2 nAChR subtypes, the binding affinity (Ki, rat) for Pozanicline to [3H] cytisine sites is 16.7 nM .
价 格:¥电议型 号:T16563产 地:中国大陆
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T12525Pozanicline dihydrochloride化合物Pozanicline dihydrochlorideABT-089 dihydrochloride
Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable agonist of nicotinic acetylcholine receptor (nAChR) (Ki = 16.7 nM)
价 格:¥电议型 号:T12525产 地:中国大陆