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T2066Quizartinib奎扎替尼;AC220
Quizartinib is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.
价 格:¥电议型 号:T2066产 地:中国大陆
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T2066QuizartinibQuizartinib,AC220,
Quizartinib is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.
价 格:¥电议型 号:T2066产 地:美洲
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T71400Quizartinib HCl;化合物 Quizartinib HClQuizartinib HCl
Quizartinib, also know as AC220 and AC010220, is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS-related tyrosine kinase 3 (FLT3/STK1), colony-stimulating factor 1 receptor (CSF1R/FMS), stem cell factor receptor (SCFR/KIT), and platelet derived growth factor receptors (PDGFRs), resulting in inhibition of ligand-independent leukemic cell pro
价 格:¥电议型 号:T71400产 地:中国大陆
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T39818Desmorpholinyl Quizartinib-PEG2-COOHDesmorpholinyl Quizartinib-PEG2-COOHDesmorpholinyl Quizartinib-P
Desmorpholinyl Quizartinib-PEG2-COOH is a compound featuring an FLT-3 ligand and a PEG-based PROTAC linker. It is employed in the synthesis of PROTAC FLT-3 degrader 1, which serves as a degrader for the FLT-3 internal tandem duplication (ITD) through PROTAC technology. The degrader exhibits an IC50 of 0.6 nM.
价 格:¥电议型 号:T39818产 地:中国大陆
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T2066Quizartinib;奎扎替尼AC220;AC220|||奎扎替尼
Quizartinib (AC220) is a second-generation type II FLT3 tyrosine kinase inhibitor that is orally active and highly selective, inhibiting the autophosphorylation of FLT3-WT and FLT3-ITD (IC50=4.1/1.1 nM). Quizartinib induces apoptosis in tumor cells.
价 格:¥电议型 号:T2066产 地:中国大陆