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T5481TRi-1
TRi-1 is irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy
价 格:¥电议型 号:T5481产 地:中国大陆
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T2276RI-1RI-1; 3-氯-1-(3,4-二氯苯基)-4-(4-吗啉基)-1H-吡咯-2,5-二酮;RI1;RI 1;RAD51 inhibitor 1
RI-1 is a RAD51 inhibitor (IC50: 5-30 μM).
价 格:¥电议型 号:T2276产 地:中国大陆
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T5481TRi-1TRi-1
TRi-1 is irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy
价 格:¥电议型 号:T5481产 地:美洲
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T83533(R)-Monlunabant;化合物 (R)-Monlunabant(R)-MRI-1891;(R)-MRI-1891
(R)-Monlunabant ((R)-MRI-1891) serves as a CB1 receptor antagonist utilized in obesity and metabolic disease research [1].
价 格:¥电议型 号:T83533产 地:中国大陆
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T82971ARI-1;化合物 ARI-1ARI-1
ARI-1 is a receptor tyrosine kinase-like orphan receptor 1 (ROR1) inhibitor that binds to ROR1´s extracellular Frizzled domain, effectively inhibiting aberrant ROR1 expression linked to non-small cell lung cancer (NSCLC) and EGFR-TKI-induced drug resistance. It modulates PI3K/AKT/mTOR signaling pathways in a ROR1-dependent manner and demonstrates potent inhibition of NSCLC cell proliferation and migration, exhibiting antitumor activity in vivo [1].
价 格:¥电议型 号:T82971产 地:中国大陆
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T79137Monlunabant;化合物 Monlunabant(S)-MRI-1891;(S)-MRI-1891
Monlunabant ((S)-MRI-1891), a solid dispersion compound, functions as an inhibitor of the cannabinoid CB1 receptor [1].
价 格:¥电议型 号:T79137产 地:中国大陆
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T5481TRi-1;化合物TRi-1TRi-1
TRi-1 is irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy
价 格:¥电议型 号:T5481产 地:中国大陆
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T39410ZevaquenabantZevaquenabant(S)-MRI-1867
Zevaquenabant ((S)-MRI-1867), a dual cannabinoid CB1 receptor and inducible NOS (iNOS) antagonist, is orally bioavailable and peripherally restricted. It effectively mitigates obesity-induced chronic kidney disease (CKD).
价 格:¥电议型 号:T39410产 地:中国大陆
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T39074(Rac)-Zevaquenabant;(Rac)-Zevaquenabant(Rac)-MRI-1867|||(Rac)-Zevaquenabant;(Rac)-MRI-1867|||(Rac)-Z
(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of the cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), exhibiting a binding affinity (Ki) of 5.7 nM specifically for CB1R. Due to its characteristics, (Rac)-Zevaquenabant holds promise as an investigative tool in liver fibrosis research.
价 格:¥电议型 号:T39074产 地:中国大陆
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T23974DDRI-18;化合物DDRI-18DDRI18|||DDRI 18;DDRI18|||DDRI 18
DDRI-18 is a novel small molecule inhibitor that regulates the DNA damage response with sensitizing and anticancer activities, inhibits non-homologous end-joining (NHEJ) DNA repair and enhances the cytotoxicity of anticancer DNA damage compounds.
价 格:¥电议型 号:T23974产 地:中国大陆
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T2276RI-1化合物RI1RI-1; 3-氯-1-(3,4-二氯苯基)-4-(4-吗啉基)-1H-吡咯-2,5-二酮|||RI1|||RAD51 inhibitor 1
RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).
价 格:¥电议型 号:T2276产 地:中国大陆