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TQ0097AGN 193109AGN193109,Autophagy,Inhibitor,Retinoic acid receptors,Retinoid X receptors,RAR/RXR,AGN 193
AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).
价 格：￥电议型 号：TQ0097产 地：中国大陆
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T21714BMS453Inhibitor,BMS453,retinoid,RAR/RXR,inhibit,BMS-453,BMS 189453,TGFβ,breast,RARβ,RARγ,Retinoid X
BMS453, a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin. BMS453 inhibits breast cell growth predominantly through the induction of active TGFβ.
价 格：￥电议型 号：T21714产 地：中国大陆
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T7370TalarozoleRetinoid X receptors,R 115866,Retinoic acid receptors,RAR/RXR,inhibit,Talarozole,Cytochrom
Talarozole is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively.Talarozole for the treatment of acne, psoriasis and other keratinization disorders.
价 格：￥电议型 号：T7370产 地：中国大陆
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T7586trifaroteneRAR/RXR,inhibit,trifarotene,CD-5789,Autophagy,RAR,Retinoid X receptors,acne,CD 5789,Retin
trifarotene is a potent and selective RARγ agonist with 65-fold and 16-fold selectivitiy for the RARγ (EC50=7.7 nM) over RARα (EC50=500 nM) and RARβ (EC50=125 nM).
价 格：￥电议型 号：T7586产 地：中国大陆
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T6696Tazaroteneinhibit,Inhibitor,Tazarotene,AGN-190168,RAR/RXR,AGN190168,Retinoic acid receptors,Autophag
Tazarotene is a synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation.
价 格：￥电议型 号：T6696产 地：中国大陆
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T6694TamibaroteneAutophagy,Apoptosis,Am-80,Tamibarotene,Retinoid X receptors,Inhibitor,Am80,RAR/RXR,Retin
Tamibarotene is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic activity.
价 格：￥电议型 号：T6694产 地：中国大陆
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T6287TariquidarXR9576；他立喹达
Tariquidar(Kd=5.1 nM) is a specific and effective non-competitive inhibitor of P-glycoprotein. It can reverse drug resistance in MDR cell Lines.
价 格：￥电议型 号：T6287产 地：中国大陆
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T29017TrxR1-IN-B19Go-Y015；TrxR1 IN B19；TrxR1INB19；Go Y015
TrxR1-IN-B19, a TrxR1 inhibitor, selectively kills gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress activation.
价 格：￥电议型 号：T29017产 地：中国大陆
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T78781TrxR1-IN-1；化合物 TrxR1-IN-1TrxR1-IN-1
Compound 5j, also known as TrxR1-IN-1, is a TrxR1 inhibitor with an IC50 of 8.8 μM. It exhibits anticancer activity, demonstrating IC50 values of 1.5 μM in MCF-7, 1.7 μM in HeLa, 2.4 μM in BGC-823, 2.8 μM in SW-480, and 2.1 μM in A549 cells. Additionally, TrxR1-IN-1 possesses antioxidant activity, effectively scavenging the DPPH radical [1].
价 格：￥电议型 号：T78781产 地：中国大陆
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T73254TrxR-IN-4；化合物 TrxR-IN-4TrxR-IN-4
Compound 1b (TrxR-IN-4) is a potent TrxR inhibitor that activates endoplasmic reticulum stress (ERS) to induce apoptosis in HepG2 cells and mitigates CCl4-induced liver damage in vivo through TrxR expression down-regulation and reduced inflammation [1].
价 格：￥电议型 号：T73254产 地：中国大陆
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T63597RXR antagonist 2；化合物 RXR antagonist 2RXR antagonist 2
RXR antagonist 2 is a potent antagonist of RXR (Ki: 0.391 μM, Kd: 0.281 μM). RXR antagonist 2 has shown research potential for RXR-related diseases.
价 格：￥电议型 号：T63597产 地：中国大陆
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T63415RXR antagonist 1；化合物 RXR antagonist 1RXR antagonist 1
RXR antagonist 1 is a Retinoid X Receptor (RXR) modulator that exhibits high RXR antagonism (pA2: 8.06). RXR antagonist 1 can be used to study type 2 diabetes.
价 格：￥电议型 号：T63415产 地：中国大陆
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T62021TrxR-IN-2；化合物 TrxR-IN-2TrxR-IN-2
TrxR-IN-2 is a potential thioredoxin reductase (TrxR) inhibitor. TrxR-IN-2 has research value in the chemotherapy of drug-resistant hepatocellular carcinoma.
价 格：￥电议型 号：T62021产 地：中国大陆
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T61647TrxR-IN-5；化合物 TrxR-IN-5TrxR-IN-5
TrxR-IN-5 (compound 4f) is an efficacious inhibitor of TrxR (thioredoxin reductase) with an IC50 of 0.16 μM. By elevating the levels of reactive oxygen species (ROS), TrxR-IN-5 fosters robust antiproliferative impacts. Additionally, TrxR-IN-5 demonstrates pronounced effects against cancer proliferation and metastasis [1].
价 格：￥电议型 号：T61647产 地：中国大陆
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T60453TrxR-IN-3；化合物 TrxR-IN-3TrxR-IN-3
TrxR-IN-3 (Compound 2c) is a effective TrxR inhibitor. TrxR-IN-3 shows strong antiproliferative activities against five human cancer cell lines, especially against breast tumor cells. TrxR-IN-3 increases ROS levels and leads to significant apoptosis by regulating the expression of apoptosis-related proteins in the breast cancer cells. TrxR-IN-3 also triggers the formation of autophagosomes and autolysosomes by promoting the expression of LC3-II and Beclin-1 and reducing the expression of LC3-I a
价 格：￥电议型 号：T60453产 地：中国大陆
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T29017TrxR1-IN-B19；化合物TrxR1-IN-B19TrxR1INB19|||Go Y015|||TrxR1 IN B19|||Go-Y015；TrxR1INB19|||Go Y015|||Trx
TrxR1-IN-B19 (TrxR1 IN B19), a TrxR1 inhibitor, selectively kills gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress activation.
价 格：￥电议型 号：T29017产 地：中国大陆
