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产品数:86101
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TQ0039(±)-Zanubrutinib
(±)-Zanubrutinib is a potent and orally available Bruton´s tyrosine kinase (Btk) inhibitor that demonstrates superior oral bioavailability, achieving higher exposure and more complete target inhibi.
价 格:¥电议型 号:TQ0039产 地:中国大陆
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TQ0236Tirabrutinib
Tirabrutinib (ONO-4059) is an orally active Bruton’s Tyrosine Kinase (Btk) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib irreversibly and covalently binds to Btk and inhibits aberrant B cell receptor signaling. Tirabrutinib can be used in studies of autoimmune diseases and hematological malignancies.
价 格:¥电议型 号:TQ0236产 地:中国大陆
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T17220Vecabrutinib
Vecabrutinib is a potent and noncovalent BTK and ITK inhibitor (Kd: 0.3 nM and 2.2 nM, respectively). Vecabrutinib displays an IC50 of 24 nM for ITK.
价 格:¥电议型 号:T17220产 地:中国大陆
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T13447(R)-Zanubrutinib
(R)-Zanubrutinib is a selective inhibitor of Bruton tyrosine kinase (BTK).
价 格:¥电议型 号:T13447产 地:中国大陆
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TQ0242Fenebrutinibinhibit,Inhibitor,GDC0853,GDC 0853,Fenebrutinib,Btk,Bruton tyrosine kinase
Fenebrutinib is a selective and noncovalent Btk inhibitor (Ki: 0.91 nM).
价 格:¥电议型 号:TQ0242产 地:中国大陆
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T7584zanubrutinibBtk,zanubrutinib,BGB3111,Inhibitor,inhibit,BGB 3111,Bruton tyrosine kinase
Zanubrutinib is an inhibitor of Bruton tyrosine kinase (BTK).
价 格:¥电议型 号:T7584产 地:中国大陆
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T9125Tolebrutinibmultiple,PRN 2246,SAR-442168,inhibit,Bruton tyrosine kinase,Tolebrutinib,sclerosis,Bruto
Tolebrutinib is a potent, selective, orally active and brain-penetrant Bruton tyrosine kinase (BTK) inhibitor(IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively). It exhibits efficacy in central nervous system immunity. Tolebrutinib can be used for the research of multiple sclerosis (MS).
价 格:¥电议型 号:T9125产 地:中国大陆
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T8636Ibrutinib deacryloylpiperidineBtk,Bruton tyrosine kinase,Inhibitor,inhibit,Ibrutinib deacryloylpiper
Ibrutinib deacryloylpiperidine is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.
价 格:¥电议型 号:T8636产 地:中国大陆
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T9408N-piperidine IbrutinibN piperidine Ibrutinib,Npiperidine Ibrutinib
N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively. N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620. SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM.
价 格:¥电议型 号:T9408产 地:中国大陆
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T5407BranebrutinibBMS986195
BMS986195 is a potent, covalent inhibitor of Bruton´s tyrosine kinase (BTK), >5,000-fold selective over all kinases outside of the Tec family (IC50 <1 nM for BTK).
价 格:¥电议型 号:T5407产 地:中国大陆
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T4S2164NarirutinIsonaringin;Naringenin-7-O-rutinoside;芸香柚皮苷;柚皮芸香苷
1. Narirutin has antiproliferative property. 2. Narirutin has anti-oxidant property. 3. Narirutin has anti-allergic and anti-inflammatory properties , can reduce airway inflammation in ovalbumin (OVA)-sensitized / challenged NC / Nga mice , a model of all
价 格:¥电议型 号:T4S2164产 地:中国大陆
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T4387evobrutinibM2951;MSC2364447C
Evobrutinib, also known as M-2951 and MSC-2364447C, is a highly selective inhibitor of the Bruton´s tyrosine kinase (BTK), which is important in the development and functioning of various immune cells including B -lymphocytes and macrophages. PreClinical
价 格:¥电议型 号:T4387产 地:中国大陆
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T3S1944DarutosideDarutin;豯莶苷
1. Darutoside can as an appropriate treatment for wounds. 2. Darutoside can improve skin elasticity, surface appearance and stretch mark removal, through soothing the skin, decreasing inflammation, restoring collagen and promoting collagen production.
价 格:¥电议型 号:T3S1944产 地:中国大陆
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T3787Didymin香风草甙;Neoponcirin;Isosakuranetin-7-O-rutinoside
Didymin has antioxidant property. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma, may used for neuroblastoma therapy. Didymin may be a potential therapeutic molecule for the treatment of neurodegenerative disorders as
价 格:¥电议型 号:T3787产 地:中国大陆
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T36287Pirtobrutinib
Pirtobrutinib (LOXO-305), a highly selective and non-covalent next generation BTK inhibitor, inhibits diverse BTK C481 substitution mutations. Pirtobrutinib causes regression of BTK-dependent lymphoma tumors in mouse xenograft models. Pirtobrutinib is als
价 格:¥电议型 号:T36287产 地:中国大陆
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T3626Acalabrutinib阿可替尼;ACP-196
Acalabrutinib, also known as ACP-196, is an orally available inhibitor of Bruton´s tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, ACP-196 inhibits the activity of BTK and prevents the activation of the B-cell antigen re
价 格:¥电议型 号:T3626产 地:中国大陆
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T2603SpebrutinibAVL-292;LMK-435;CC-292
Spebrutinib is an orally bioavailable, selective inhibitor of Bruton´s agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity.
价 格:¥电议型 号:T2603产 地:中国大陆
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T22417Rutin hydrate芸香苷,芸香素,芦丁;Quercetin-3-O-rutinoside;Rutoside;Sophorin
Rutin hydrate, a kind of glycoside, widely exists in many plants including citrus fruit.
价 格:¥电议型 号:T22417产 地:中国大陆
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T1835IbrutinibPCI-32765;伊布替尼;依鲁替尼
Ibrutinib is an irreversible inhibitor of BTK (IC50: 0.5 nM) that selectively blocks B cell activation.
价 格:¥电议型 号:T1835产 地:中国大陆
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T16730Remibrutinib
Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib is an effective and orally active Bruton tyrosine kinase inhibitor (IC50: 1 nM). Remibrutinib has the potential for Chronic urticaria (CU) treatment.
价 格:¥电议型 号:T16730产 地:中国大陆