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T6403Siponimodinflammation,BAF312,Lysophospholipid Receptor,S1P receptor,inhibit,neurodegeneration,S1P1 a
BAF312 (Siponimod), a next-generation S1P receptor modulator, is specific for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, respectively. The specificity of BAF312 for S1P1 and S1P5 receptors exhibits >1000-fold over S1P2, S1P3 and S1P4 receptors.
价 格：￥电议型 号：T6403产 地：中国大陆
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T16833S1P1 Agonist IIIS1P1 Agonist III
S1P1 Agonist III is an effective and orally active S1P1 agonist (EC50: 18 nM).
价 格：￥电议型 号：T16833产 地：美洲
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T79817S1P1 agonist 6 hemicalcium；化合物 S1P1 agonist 6 hemicalciumS1P1 agonist 6 hemicalcium
Compound I (S1P1 agonist 6 hemicalcium) is an S1P1 agonist that diminishes autoimmune activity by inhibiting lymphocyte trafficking, and serves as an immunosuppressive agent in researching a range of autoimmune diseases [1].
价 格：￥电议型 号：T79817产 地：中国大陆
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T79816S1P1 agonist 6；化合物 S1P1 agonist 6S1P1 agonist 6
Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive agent in autoimmune disease research [1].
价 格：￥电议型 号：T79816产 地：中国大陆
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T62732S1P1 agonist 5；化合物 S1P1 agonist 5S1P1 agonist 5
S1P1 agonist 5 is a selective, orally active S1P1 agonist. S1P1 agonist 5 inhibits the drainage of lymphocytes from lymphoid tissue into peripheral blood. S1P1 agonist 5 has potential for studies in multiple sclerosis (MS).
价 格：￥电议型 号：T62732产 地：中国大陆
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T61639S1P1 agonist 4；化合物 S1P1 agonist 4S1P1 agonist 4
S1P1 agonist 4 exhibits enhanced potency with an EC 50 value of less than 0.05 mg/kg and a predicted human half-life (t1/2) of approximately 5 days, indicating a favorable pharmacological profile.
价 格：￥电议型 号：T61639产 地：中国大陆
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T38716SAR247799；SAR247799SAR247799|||S1P1 agonist 3；SAR247799|||S1P1 agonist 3
SAR247799 (S1P1 agonist 3) is an orally-active, selective G-protein-biased agonist for the sphingosine-1 phosphate receptor-1 (S1P1). It demonstrates EC50 values ranging from 12.6 to 493 nM in S1P1-overexpressing cells and HUVECs. SAR247799 holds promise as a valuable tool for investigating endothelial protection, particularly in the context of type-2 diabetes and metabolic syndrome[4].
价 格：￥电议型 号：T38716产 地：中国大陆
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T28643Ex26；化合物 Ex26S1P1-IN-Ex26；S1P1-IN-Ex26
Ex26 (S1P1-IN-Ex26) is a selective and potent sphingosine 1-phosphate receptor 1 (S1P1) antagonist that disrupts SR-B1-S1PR1 interactions and inhibits S1P-S1PR1 signaling.Ex26 can be used in experimental autoimmune encephalomyelitis, arterial Ex26 is used in experimental autoimmune encephalomyelitis, atherosclerosis and gastric cancer.
价 格：￥电议型 号：T28643产 地：中国大陆
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T16833S1P1 Agonist III；化合物 T16833S1P1 Agonist III
S1P1 Agonist III is an effective and orally active S1P1 agonist (EC50: 18 nM).
价 格：￥电议型 号：T16833产 地：中国大陆
