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T4229S1RA hydrochlorideE-52862 hydrochloride;4-[2-[[5-甲基-1-(2-萘基)-1H-吡唑-3-基]氧基]乙基]吗啉盐酸盐(1:1)
S1RA HCl (E-52862 HCl) is an effective and specific sigma-1 receptor(σ1R, Ki: 17 nM) antagonist, and has good selectivity against σ2R (Ki > 1000 nM).
价 格:¥电议型 号:T4229产 地:中国大陆
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T78954hNTS1R agonist-1;化合物 hNTS1R agonist-1hNTS1R agonist-1
Compound 10, an hNTS1R agonist-1, acts as a full agonist with a strong affinity for hNTS1R (K i: 6.9 nM), showing the ability to cross the blood-brain barrier (BBB). It not only enhances motor function but also improves memory in a mouse model of Parkinson´s disease (PD). Additionally, this compound is an analog of Neurotensin(8-13) and demonstrates neuroprotective properties [1].
价 格:¥电议型 号:T78954产 地:中国大陆
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T78087S1R agonist 2 hydrochloride;化合物 S1R agonist 2 hydrochlorideS1R agonist 2 hydrochloride
Compound 8b hydrochloride, a selective S1R agonist, exhibits affinity with K i s of 1.1 nM for S1R and 88 nM for S2R. It demonstrates neuroprotective effects against ROS and NMDA-induced neurotoxicity [1].
价 格:¥电议型 号:T78087产 地:中国大陆
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T78086S1R agonist 1 hydrochloride;化合物 S1R agonist 1 hydrochlorideS1R agonist 1 hydrochloride
S1R Agonist 1 (Compound 6b) hydrochloride is a selective S1R agonist, displaying K i values of 0.93 nM for S1R and 72 nM for S2R, and has demonstrated neuroprotective effects against ROS and NMDA-induced neurotoxicity [1].
价 格:¥电议型 号:T78086产 地:中国大陆
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T74822S1R agonist 1;化合物 S1R agonist 1S1R agonist 1
Compound 6b, also known as S1R agonist 1, is a selective agonist for S1R with dissociation constants (Ki) of 0.93 nM for S1R and 72 nM for S2R. This compound demonstrates neuroprotective effects against reactive oxygen species (ROS) and NMDA-induced neurotoxicity [1].
价 格:¥电议型 号:T74822产 地:中国大陆
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T72059S1R agonist 2;化合物S1R agonist 2S1R agonist 2
S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.
价 格:¥电议型 号:T72059产 地:中国大陆
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T4229S1RA hydrochloride;化合物S1RA hydrochlorideE-52862 hydrochloride;4-[2-[[5-甲基-1-(2-萘基)-1H-吡唑-3-基]氧基]乙基]吗
S1RA hydrochloride (E-52862 hydrochloride) is an effective and specific sigma-1 receptor(σ1R, Ki: 17 nM) antagonist, and has good selectivity against σ2R (Ki > 1000 nM).
价 格:¥电议型 号:T4229产 地:中国大陆
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T1865S1RA;化合物S1RAE-52862;E-52862|||4-(2-((5-甲基-1-(2-萘基)-1H-吡唑-3-基)氧基)乙基)吗啉
S1RA (E-52862)(E-52862) is a potent, selective antagonist of the sigma-1 receptor (σ1R, Ki=17 nM), demonstrating significant selectivity over the sigma-2 receptor (σ2R, Ki > 1000 nM).
价 格:¥电议型 号:T1865产 地:中国大陆