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产品数:86101
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已选条件
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T7848PT-2385Inhibitor,inhibit,Hypoxia-inducible factors,HIF/HIF Prolyl-Hydroxylase,HIF-PH,PT 2385,HIFs,PT
PT-2385 is a selective HIF-2α inhibitor (Kd<50 nM).
价 格:¥电议型 号:T7848产 地:中国大陆
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TP1559LZiconotide Acetate (107452-89-1 free base)analgesic,non-opioid,Ziconotide Acetate (107452891 free
Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects.
价 格:¥电议型 号:TP1559L产 地:中国大陆
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TP1881L1Pep 2-8 ammonium salt(1541011-97-5 free base)Pep 2 8 ammonium salt(1541011 97 5 free base),Pep 28 am
Pep 2-8 ammonium salt is Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.
价 格:¥电议型 号:TP1881L1产 地:中国大陆
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TP1789LMalantide acetate(86555-35-3 free base)Malantide acetate(86555 35 3 free base),Malantide acetate(865
Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide that is phosphorylated by PKA and is used to measure PKA activity in vitro.
价 格:¥电议型 号:TP1789L产 地:中国大陆
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T9192BIIB068ADME,inhibit,FcγR,Autoimmune,Bruton tyrosine kinase,TNFα,BIIB 068,ROS,Inhibitor,reversible,Bt
BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.
价 格:¥电议型 号:T9192产 地:中国大陆
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TP1898HS024selective,melanocortin,intake,Inhibitor,Melanocortin Receptor,MC Receptor,HS-024,food,HS024,inh
Highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo.
价 格:¥电议型 号:TP1898产 地:中国大陆
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TJS03384-Methylesculetininhibit,4 Methylesculetin,Glutathione Peroxidase,4-Methylesculetin,Inhibitor,4Methy
4-methylesculetin is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities.
价 格:¥电议型 号:TJS0338产 地:中国大陆
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T67777Flaviviruses-IN-3
Flaviviruses-IN-3 (compound 87) is a potent inhibitor of flaviviruse. Flaviviruses-IN-3 could reduce the WNV (West Nile virus) protease activity, with a inhibition of 54%.
价 格:¥电议型 号:T67777产 地:中国大陆
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TN2100PratenseinInhibitor,Nuclear factor-kappaB,Nuclear factor-κB,cognitive,inhibit,BDNF,synapse,Pratensei
Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.
价 格:¥电议型 号:TN2100产 地:中国大陆
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TP1882L1Orphanin FQ(1-11) acetate(178249-41-7 free base)Orphanin FQ(1 11) acetate(178249 41 7 free base),Orp
Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Displays analgesic properties in CD-1 mice.
价 格:¥电议型 号:TP1882L1产 地:中国大陆
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T8796CAN508inhibit,CAN 508,ATP-competitive,Cyclin dependent kinase,esophageal,cells,CDK,CAN508,Inhibitor,
CAN508 is a potent, ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 μM. It is also a competitive inhibitor of Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 and 20 μM, respectively.CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. Antitumor activity.
价 格:¥电议型 号:T8796产 地:中国大陆
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T7741DS-1001binhibit,DS 1001b,Inhibitor,Isocitrate Dehydrogenase (IDH),DS-1001b,DS1001b
DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)
价 格:¥电议型 号:T7741产 地:中国大陆
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T9041AES-350Histone deacetylases,AES 350,MV4-11,AES-350,Apoptosis,acute myeloid leukemia,AML,Inhibitor,in
AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, and >1μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.
价 格:¥电议型 号:T9041产 地:中国大陆
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T6908NSC 228155Epidermal growth factor receptor,Histone Acetyltransferase,EGFR,HER1,HATs,inhibit,Inhibito
NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
价 格:¥电议型 号:T6908产 地:中国大陆
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T6767TCS7010Aurora Kinase,inhibit,TCS 7010,Apoptosis,TCS-7010,TCS7010,Inhibitor
Aurora A Inhibitor I is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B.
价 格:¥电议型 号:T6767产 地:中国大陆
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T14526Bemesetron
Bemesetron is a selective antagonist of 5-HT3 (IC50 = 0.33 nM) with neuroprotective effects.
价 格:¥电议型 号:T14526产 地:中国大陆
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T7815LAOD9604 acetate(221231-10-3 free base)AOD9604 acetate(221231103 free base),AOD-9604 acetate(221231-1
AOD9604 acetate is a potential anti-obesity peptide based on the human growth hormone.
价 格:¥电议型 号:T7815L产 地:中国大陆
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T6443Chloroprocaine hydrochlorideinhibit,Na,K-ATPase,Sodium potassium pump,Chloroprocaine,anesthetic,2-Ch
Chloroprocaine HCl is a local anesthetic during surgical procedures.
价 格:¥电议型 号:T6443产 地:中国大陆
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T7596FirocoxibLPS,COX-2,fever,ML1785713,Cyclooxygenase,COX,inhibit,Firocoxib,Inhibitor,anti-inflammatory,
Firocoxib is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.
价 格:¥电议型 号:T7596产 地:中国大陆
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T8222SelpercatinibFVB/NRj mice,RET (WT),inhibit,Inhibitor,RET (G810R),LOXO 292,LOXO292,RET (V804M),Selper
Selpercatinib is a tyrosine kinase inhibitor with antineoplastic properties(IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively)
价 格:¥电议型 号:T8222产 地:中国大陆