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T9192BIIB068ADME,inhibit,FcγR,Autoimmune,Bruton tyrosine kinase,TNFα,BIIB 068,ROS,Inhibitor,reversible,Bt
BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.
价 格：￥电议型 号：T9192产 地：中国大陆
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T6883SamotolisibInhibitor,mTOR,LY-3023414,Phosphoinositide 3-kinase,DNA-dependent protein kinase,inhibit,
LY3023414 is an oral ATP competitive inhibitor of the class I PI3K isoforms, DNA-PK, and mTOR. LY3023414 has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, BREAST CANCER, and Advanced Cancer, among others.
价 格：￥电议型 号：T6883产 地：中国大陆
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T9121AG-636inhibit,oral,AG 636,AG-636,reversible,DHODH,anticancer,AG636,Inhibitor,Dihydroorotate Dehydrog
AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.
价 格：￥电议型 号：T9121产 地：中国大陆
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T8684SotorasibAMG 510,Ras,KRAS,covalent,Sotorasib,regression,mutation,Inhibitor,G12C,anti-tumour,inhibit,
AMG-510 is a selective and orally bioavailable KRAS G12C covalent inhibitor.
价 格：￥电议型 号：T8684产 地：中国大陆
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T9045BemotrizinolBemotrizinol,inhibit,atomic oxygen,Tinosorb S,Inhibitor,feasible acceptor
Bemotrizinol is a UVA absorber used as a topical sunscreen.
价 格：￥电议型 号：T9045产 地：中国大陆
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TQ0044SeletalisibInhibitor,Phosphoinositide 3-kinase,Seletalisib,UCB-5857,UCB 5857,inhibit,PI3K
Seletalisib (UCB5857) is a potent and specific PI3Kδ inhibitor (IC50: 12 nM).
价 格：￥电议型 号：TQ0044产 地：中国大陆
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T60061RU-TRAAK-2RU TRAAK 2,inhibit,Inhibitor,channels,reversible,TRAAK non-K2P,Potassium Channel,RUTRAAK2,
RU-TRAAK-2 is a reversible inhibitor of TWIK-related arachidonic acid-stimulated K+ channel with no activity for non-K2P channels including Kv1.2, GIRK2, and Slo1.
价 格：￥电议型 号：T60061产 地：中国大陆
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TQ0318Filanesib
Filanesib is a selective inhibitor of kinesin spindle protein (KSP, IC50 = 6 nM) with potent anti-proliferative activity.
价 格：￥电议型 号：TQ0318产 地：中国大陆
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T22657Laduviglusib trihydrochloride
Laduviglusib trihydrochloride is a selective glycogen synthase kinase 3 (GSK-3) inhibitor with IC50s of 10 nM and 6.7 nM for GSK-3α and GSK-3β. Laduviglusib trihydrochloride inhibits human GSK-3β with a Ki of 9.8 nM. Laduviglusib trihydrochloride is an activator of Wnt/β-catenin signaling. Laduviglusib trihydrochloride induces autophagy.
价 格：￥电议型 号：T22657产 地：中国大陆
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T8369Adagrasibinhibit,GDP-bound,mutant,MIA PaCa-2,MRTX-849,Adagrasib,selective,Inhibitor,MRTX 849,inactiv
MRTX849 is a potent, selective and covalent KRASG12C inhibitor with potential antineoplastic activity. It selectively modifies mutant cysteine 12 in GDP-bound KRASG12C, and inhibits KRAS-dependent signaling.
价 格：￥电议型 号：T8369产 地：中国大陆
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T7014VoxtalisibSAR-245409,SAR 245409,inhibit,Phosphoinositide 3-kinase,Mammalian target of Rapamycin,XL 7
Voxtalisib (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.
价 格：￥电议型 号：T7014产 地：中国大陆
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T77882-Phenyl-2-(1-piperidinyl)propane2 Phenyl 2 (1 piperidinyl)propane,Reversible,inhibit,CYPs,Cytochrom
2-Phenyl-2-(1-piperidinyl)propane (PPP), an analog of phencyclidine
价 格：￥电议型 号：T7788产 地：中国大陆
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T60076Oritinibpharmacodynamics,non-small cell lung cancer,EGFR-T790M,EGFR TKI,SH1028,Irreversible,mutant-s
Oritinib is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can be used in studies about the treatment of non-small cell lung cancer.
价 格：￥电议型 号：T60076产 地：中国大陆
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T8421TED-347PPI,irreversible,protein-protein,YAP,allosteric,TEAD4?Yap1,transcriptional,glioblastoma,TED 3
TED-347 is an irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.
价 格：￥电议型 号：T8421产 地：中国大陆
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TN119517-Hydroxy sprengerinin CPolygonatum sibiricum,17Hydroxy sprengerinin C,17-Hydroxy sprengerinin C,pr
17-Hydroxy sprengerinin C is a glycoside compound isolated from rhizomes of Polygonatum sibiricum with stronger anticancer activities. 17-Hydroxy sprengerinin C reduces the expression of Blc-2 and pro-caspase3 and increases the production of Bax.
价 格：￥电议型 号：TN1195产 地：中国大陆
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T36395Trotabresib
CC-90010 is an orally active inhibitor of BET and can be used in studies about advanced solid tumors.
价 格：￥电议型 号：T36395产 地：中国大陆
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T9399Menin-MLL inhibitor 20Epigenetic Reader Domain,mixed-lineage,MeninMLL inhibitor 20,irreversible,leuk
Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities (WO2020142557A1, compound 6).
价 格：￥电议型 号：T9399产 地：中国大陆
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T11129LDuvelisib (R enantiomer) hydrochloride
Duvelisib (R enantiomer) hydrochloride is a PI3K inhibitor. Duvelisib (R enantiomer) hydrochloride is the less active enantiomer of Duvelisib.
价 格：￥电议型 号：T11129L产 地：中国大陆
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T8495AlobresibInhibitor,GS5829,Alobresib,GS 5829,Epigenetic Reader Domain,inhibit
Alobresib is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.
价 格：￥电议型 号：T8495产 地：中国大陆
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T8434SIB-1757SIB-1757,mGluR,SIB1757,Metabotropic glutamate receptors,inhibit,Inhibitor,SIB 1757
SIB-1757 is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)
价 格：￥电议型 号：T8434产 地：中国大陆
