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T60029SOS1-IN-11inhibit,Inhibitor,Ras,SOS1IN11,SOS1 IN 11
SOS1-IN-11 is an effective inhibitor of SOS1 (IC50 = 30 nM).
价 格：￥电议型 号：T60029产 地：中国大陆
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T79183SOS1-IN-16；化合物 SOS1-IN-16SOS1-IN-16
SOS1-IN-16 (Comp 54) serves as a selective SOS1 inhibitor exhibiting an IC50 value of 7.2 nM and demonstrates inhibitory activity against CYP3A4 with an IC50 of 8.9μM when testosterone is employed as a substrate. This compound is utilized in cancer research [1].
价 格：￥电议型 号：T79183产 地：中国大陆
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T79162SOS1/KRAS-IN-1；化合物 SOS1/KRAS-IN-1SOS1/KRAS-IN-1
SOS1/KRAS-IN-1 (Compound 2) serves as an inhibitor of SOS1/KRAS, with potential application in the study of diseases mediated by SOS1/KRAS [1].
价 格：￥电议型 号：T79162产 地：中国大陆
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T79098PROTAC SOS1 degrader-4；化合物 PROTAC SOS1 degrader-4PROTAC SOS1 degrader-4
PROTAC SOS1 Degrader-4 (compound 10) is a potent degrader of SOS1 and exhibits antiproliferative activity [1].
价 格：￥电议型 号：T79098产 地：中国大陆
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T76059SAH-SOS1A TFA；SAH-SOS1A TFASAH-SOS1A TFA
SAH-SOS1A TFA is a peptide-based SOS1/KRAS protein interaction inhibitor. SAH-SOS1A TFA binds to wild-type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity ( EC 50 =106-175 nM). SAH-SOS1A TFA directly and independently blocks nucleotide association. SAH-SOS1A TFA impairs KRAS-driven cancer cell viability and exerts its effects by on-mechanism blockade of the ERK-MAPK phosphosignaling cascade downstream of KRAS [1] .
价 格：￥电议型 号：T76059产 地：中国大陆
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T75020PROTAC SOS1 degrader-3；化合物 PROTAC SOS1 degrader-3PROTAC SOS1 degrader-3
PROTAC SOS1 Degrader-3 is a potent agent specifically designed to target and degrade SOS1 via the ubiquitin-proteasome system [1].
价 格：￥电议型 号：T75020产 地：中国大陆
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T74439PROTAC SOS1 degrader-1；化合物 PROTAC SOS1 degrader-1PROTAC SOS1 degrader-1
PROTAC SOS1 degrader-1, a potent compound, demonstrates an effective degradation of PROTAC SOS1 with a DC50 value of 98.4 nM. It exhibits antiproliferative activity against cancer cells harboring diverse KRAS mutations and has shown an antitumor effect with low toxicity [1].
价 格：￥电议型 号：T74439产 地：中国大陆
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T74356PROTAC SOS1 degrader-2；化合物 PROTAC SOS1 degrader-2PROTAC SOS1 degrader-2
PROTAC SOS1 degrader-2, a potent degrader of PROTAC SOS1, effectively reduces the expression of pERK and RAS-GTP in a dose-dependent manner. It significantly inhibits tumor growth in vivo [1].
价 格：￥电议型 号：T74356产 地：中国大陆
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T73164SOS1-IN-15；SOS1 抑制剂15SOS1-IN-15
SOS1-IN-15 is an orally active and potent SOS1 inhibitor with potential antitumor activity.SOS1-IN-15 is used in the study of colon cancer.
价 格：￥电议型 号：T73164产 地：中国大陆
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T63781SOS1-IN-5；化合物 SOS1-IN-5SOS1-IN-5
SOS1-IN-5 is a pyrimidine bicyclic derivative and a potent inhibitor of SOS1. SOS1-IN-5 interferes with the RAS-SOS1 interaction, thereby blocking KRAS activation and exhibiting broad-spectrum inhibition of KRAS activity. compound 4).
价 格：￥电议型 号：T63781产 地：中国大陆
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T63118SOS1-IN-8；化合物 SOS1-IN-8SOS1-IN-8
SOS1-IN-8 is an inhibitor of SOS1 and acts on SOS1-G12D (IC50: 11.6 nM) and SOS1-G12V (IC50: 40.7 nM).
价 格：￥电议型 号：T63118产 地：中国大陆
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T63083SOS1-IN-4；化合物 SOS1-IN-4SOS1-IN-4
SOS1-IN-4 is a potent inhibitor of SOS1 (IC50: 56 nM) and can be used in the study of KRAS-C12C/SOS1 interactions.
价 格：￥电议型 号：T63083产 地：中国大陆
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T63044SOS1-IN-6；化合物 SOS1-IN-6SOS1-IN-6
SOS1-IN-6 (compound 33-P1) is a potent inhibitor of SOS1, acting on SOS1-G12D (IC50: 14.9 nM) and SOS1-G12V (IC50: 73.3 nM).
价 格：￥电议型 号：T63044产 地：中国大陆
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T62923SOS1-IN-7；化合物 SOS1-IN-7SOS1-IN-7
SOS1-IN-7 (compound 18-p1) is a potent inhibitor of SOS1 and acts on SOS1-G12D (IC50: 20 nM) and SOS1-G12V (IC50: 67 nM).
价 格：￥电议型 号：T62923产 地：中国大陆
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T62712SOS1-IN-10；化合物 SOS1-IN-10SOS1-IN-10
SOS1-IN-10 is a potent inhibitor of SOS1 that acts on KRAS G12C-SOS1 (IC50: 13 nM).
价 格：￥电议型 号：T62712产 地：中国大陆
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T62478SOS1-IN-9；化合物 SOS1-IN-9SOS1-IN-9
SOS1-IN-9 is a potent inhibitor of SOS1 that acts on KRAS G12C-SOS1 (IC50: 116.5 nM).
价 格：￥电议型 号：T62478产 地：中国大陆
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T62371SOS1-IN-12；化合物 SOS1-IN-12SOS1-IN-12
SOS1-IN-12 is a potent inhibitor of SOS1, acting on SOS1 (Ki: 0.11 nM) and on pERK (IC50: 47 nM).
价 格：￥电议型 号：T62371产 地：中国大陆
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T62003SOS1-IN-13；化合物 SOS1-IN-13SOS1-IN-13
SOS1-IN-13 is a potent inhibitor of son of sevenless homolog 1 (SOS1). SOS1-IN-13 shows IC 50 s of 6.5 nM and 327 nM for SOS1 and pERK, respectively. SOS1-IN-13 has research value in anticancer.
价 格：￥电议型 号：T62003产 地：中国大陆
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T61963SOS1-IN-3；化合物 SOS1-IN-3SOS1-IN-3
SOS1-IN-3 is an effective inhibitor of SOS1 (son of sevenless homolog 1) (IC50=5 nM). SOS1-IN-3 shows antitumor activity.
价 格：￥电议型 号：T61963产 地：中国大陆
