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产品数:86101
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已选条件
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T7123AMG-47aInhibitor,signal,kinases,AMG 47a,JAK,Janus kinase,AMG-47a,transduction,Src,VEGFR,cytoplamic,p
AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells.
价 格:¥电议型 号:T7123产 地:中国大陆
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T7622GabazineInhibitor,Gamma-aminobutyric acid Receptor,Gabazine,γ-Aminobutyric acid Receptor,inhibit,SR
Gabazine is an antagonist of GABAA receptors (Ki : 74-150 nM)
价 格:¥电议型 号:T7622产 地:中国大陆
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TQ0187SR-3677Inhibitor,Rho-associated protein kinase,Autophagy,SR 3677,Rho-kinase,SR3677,ROCK,ROK,SR-3677,
SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).
价 格:¥电议型 号:TQ0187产 地:中国大陆
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T8403CinacalcetAMG-073,Calcium-sensing receptor,Endogenous Metabolite,Inhibitor,CaSR,Cinacalcet,inhibit,A
Cinacalcet is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease .
价 格:¥电议型 号:T8403产 地:中国大陆
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T6896TolimidoneSrc,Tolimidone,MLR 1023,MLR1023,Inhibitor,inhibit
MLR-1023 is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.
价 格:¥电议型 号:T6896产 地:中国大陆
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TQ0022Capromorelin TartrateInhibitor,Growth hormone secretagogue receptor,GHSR,Capromorelin,inhibit,Caprom
Capromorelin Tartrate is a potent, orally active growth hormone secretagogue receptor (GHSR) agonist (Ki: 7 nM for hGHS-R1a).
价 格:¥电议型 号:TQ0022产 地:中国大陆
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T10896LCSRM617 hydrochloride
CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2, a master regulator of androgen receptor) with a K d of 7.43 uM in SPR assays, directly binds to OC2-HOX domain. CSRM617 hydrochloride induces apoptosis through the appearance of cleaved Caspase-3 and PARP. CSRM617 hydrochloride is well tolerated in the mouse model of prostate cancer [1]
价 格:¥电议型 号:T10896L产 地:中国大陆
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T11217Eplivanserin5-hydroxytryptamine Receptor,Serotonin Receptor,5-HT2A,5-HT Receptor,Eplivanserin,SR4634
Eplivanserin is an effective and selective antagonist of 5-HT2A receptor with a Kd of 1.14 nM and an IC50 value of 5.8 nM in rat cortical membrane.
价 格:¥电议型 号:T11217产 地:中国大陆
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T7837SR8278Duchenne muscular dystrophy,inhibit,metabolism,biological rhythm,Alzheimer’s disease,SR-8278,S
SR8278 is an REV-ERBα antagonist(EC50 = 0.47 μM), blocking activation of the receptor by the synthetic agonist GSK 4112
价 格:¥电议型 号:T7837产 地:中国大陆
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T6832Fatostatin hydrobromideGolgi,ob/ob,inhibit,Fatostatin hydrobromide,prostate,SREBP-mediated,cancer,mi
Fatostatin ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.
价 格:¥电议型 号:T6832产 地:中国大陆
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T7522GI254023XSRI 028594,SRI028594,GI 4023,inhibit,GI-254023X,Matrix metalloproteinases,SRI-028594,Inhibi
GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can remarkably inhibit the proliferation and induce the apoptosis of H929 cells. Its mechanism may be associated with inbihition of Notch1 activation.
价 格:¥电议型 号:T7522产 地:中国大陆
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T73711-Naphthyl PP1 hydrochloride1 Naphthyl PP1 hydrochloride,Src,1Naphthyl PP1 hydrochloride,1-Naphthyl
1-Naphthyl PP1 hydrochloride is a selective inhibitor of src family kinases v-Src
价 格:¥电议型 号:T7371产 地:中国大陆
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T7904SR 19881SR-19881,estrogen-related receptor,nuclear receptor,amide,SR19881,phenol,ligand binding doma
SR 19881 is a full agonist of ERRγ(EC50 value of 0.39 μM in a binding assay and an EC50 value of 4.7 μM in a cell-based assay).
价 格:¥电议型 号:T7904产 地:中国大陆
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TP1236Etelcalcetide hydrochlorideEtelcalcetide hydrochloride,KAI-4169,AMG416,KAI4169,CaSR,KAI 4169,AMG 416
Etelcalcetide hydrochloride is a synthetic peptide as an allosteric modulator of the calcium (Ca)-sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis.
价 格:¥电议型 号:TP1236产 地:中国大陆
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T76946-fluoro-DL-Tryptophan6 fluoro DL Tryptophan,Tryptophan Hydroxylase,inhibit,disruption of sleep,6-Fl
6-fluoro-DL-Tryptophan is an inhibitor of serotonin (5-HT) synthesis.
价 格:¥电议型 号:T7694产 地:中国大陆
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T6482Efaproxiral SodiumRSR-13,RSR13,Reactive Oxygen Species,RSR 13,Efaproxiral Sodium,Inhibitor,inhibit,E
Efaproxiral Sodium , a synthetic allosteric modifier of hemoglobin, is utilized for brain metastases originating from breast cancer.
价 格:¥电议型 号:T6482产 地:中国大陆
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T6594MNSthrombin,aggregation,NSC170724,Inhibitor,Src,MNS,NSC 170724,activation,inhibit,NSC-170724,Spleen
MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
价 格:¥电议型 号:T6594产 地:中国大陆
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T8847Fosravuconazole L-lysine ethanolateFungal,onychomycosis,Fosravuconazole Llysine ethanolate,Parasite,
FosravuconazoleL-lysine ethanolate is a broad-spectrum antifungal agent. In Japan, it is approved for the treatment of onychomycosis, a fungal infection of the nail. It is a prodrug that is converted into ravuconazole.
价 格:¥电议型 号:T8847产 地:中国大陆
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T8655SR-717immunity,MPYS,MITA,inhibit,ISG-THP1,Inhibitor,SR 717,mimetic,TMEM173,STING,SR717,cGAMP,THP1,an
SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. Antitumor activity[1].
价 格:¥电议型 号:T8655产 地:中国大陆